Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
Nieborowska-Skorska, Margaret, Kopinski, Piotr K., Ray, Regina, Hoser, Grazyna, Ngaba, Danielle, Flis, Sylwia, Cramer, Kimberly, Reddy, Mamatha M., Koptyra, Mateusz, Penserga, Tyrone, Glodkowska-Mrowka, Eliza, Bolton, Elisabeth, Holyoake, Tessa L., Eaves, Connie J., Cerny-Reiterer, Sabine, Valent, Peter, Hochhaus, Andreas, Hughes, Timothy P., van der Kuip, Heiko, Sattler, Martin, Wiktor-Jedrzejczak, Wieslaw, Richardson, Christine, Dorrance, Adrienne, Stoklosa, Tomasz, Williams, David A., Skorski, Tomasz
Published in Blood (03.05.2012)
Published in Blood (03.05.2012)
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High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFκB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts
Rudisch, Albin, Dewhurst, Matthew Richard, Horga, Luminita Gabriela, Kramer, Nina, Harrer, Nathalie, Dong, Meng, van der Kuip, Heiko, Wernitznig, Andreas, Bernthaler, Andreas, Dolznig, Helmut, Sommergruber, Wolfgang
Published in PloS one (28.04.2015)
Published in PloS one (28.04.2015)
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Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy
Silkenstedt, Elisabeth, Arenas, Fabian, Colom-Sanmartí, Berta, Xargay-Torrent, Sílvia, Higashi, Morihiro, Giró, Ariadna, Rodriguez, Vanina, Fuentes, Patricia, Aulitzky, Walter E, van der Kuip, Heiko, Beà, Sílvia, Toribio, Maria L, Campo, Elias, López-Guerra, Mònica, Colomer, Dolors
Published in Journal of experimental & clinical cancer research (01.11.2019)
Published in Journal of experimental & clinical cancer research (01.11.2019)
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Dual targeting of MCL1 and NOXA as effective strategy for treatment of mantle cell lymphoma
Höring, Elisabeth, Montraveta, Arnau, Heine, Simon, Kleih, Markus, Schaaf, Lea, Vöhringer, Matthias C., Esteve‐Arenys, Anna, Roué, Gael, Colomer, Dolors, Campo, Elias, Ott, German, Aulitzky, Walter E., Kuip, Heiko
Published in British journal of haematology (01.05.2017)
Published in British journal of haematology (01.05.2017)
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Journal Article
Cancer Cells Cue the p53 Response of Cancer-Associated Fibroblasts to Cisplatin
SCHMID, Jens O, MENG DONG, DER KUIP, Heiko Van, HAUBEISS, Silke, FRIEDEL, Godehard, BODE, Sabine, GRABNER, Andreas, OTT, German, MÜRDTER, Thomas E, OREN, Moshe, AULITZKY, Walter E
Published in Cancer research (Chicago, Ill.) (15.11.2012)
Published in Cancer research (Chicago, Ill.) (15.11.2012)
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Dasatinib reverses cancer-associated fibroblasts (CAFs) from primary lung carcinomas to a phenotype comparable to that of normal fibroblasts
Haubeiss, Silke, Schmid, Jens O, Mürdter, Thomas E, Sonnenberg, Maike, Friedel, Godehard, van der Kuip, Heiko, Aulitzky, Walter E
Published in Molecular cancer (27.06.2010)
Published in Molecular cancer (27.06.2010)
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Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo
Hickman, John A, Graeser, Ralph, de Hoogt, Ronald, Vidic, Suzana, Brito, Catarina, Gutekunst, Matthias, van der Kuip, Heiko
Published in Biotechnology journal (01.09.2014)
Published in Biotechnology journal (01.09.2014)
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Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast
Sonnenberg, Maike, van der Kuip, Heiko, Haubeis, Silke, Fritz, Peter, Schroth, Werner, Friedel, Godehard, Simon, Wolfgang, Mürdter, Thomas E, Aulitzky, Walter E
Published in BMC cancer (11.12.2008)
Published in BMC cancer (11.12.2008)
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Short term culture of breast cancer tissues to study the activity of the anticancer drug taxol in an intact tumor environment
van der Kuip, Heiko, Mürdter, Thomas E, Sonnenberg, Maike, McClellan, Monika, Gutzeit, Susanne, Gerteis, Andreas, Simon, Wolfgang, Fritz, Peter, Aulitzky, Walter E
Published in BMC cancer (07.04.2006)
Published in BMC cancer (07.04.2006)
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Imaging of myocardial infarction using ultrasmall superparamagnetic iron oxide nanoparticles: a human study using a multi-parametric cardiovascular magnetic resonance imaging approach
Yilmaz, Ali, Dengler, Michael A, van der Kuip, Heiko, Yildiz, Handan, Rösch, Sabine, Klumpp, Siegfried, Klingel, Karin, Kandolf, Reinhard, Helluy, Xavier, Hiller, Karl-Heinz, Jakob, Peter M, Sechtem, Udo
Published in European heart journal (01.02.2013)
Published in European heart journal (01.02.2013)
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Journal Article
p53 hypersensitivity is the predominant mechanism of the unique responsiveness of testicular germ cell tumor (TGCT) cells to cisplatin
Gutekunst, Matthias, Oren, Moshe, Weilbacher, Andrea, Dengler, Michael A, Markwardt, Christiane, Thomale, Jürgen, Aulitzky, Walter E, van der Kuip, Heiko
Published in PloS one (21.04.2011)
Published in PloS one (21.04.2011)
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Journal Article
Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA
Heine, Simon, Kleih, Markus, Giménez, Neus, Böpple, Kathrin, Ott, German, Colomer, Dolors, Aulitzky, Walter E, van der Kuip, Heiko, Silkenstedt, Elisabeth
Published in Journal of hematology and oncology (04.09.2018)
Published in Journal of hematology and oncology (04.09.2018)
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Journal Article
Cisplatin Hypersensitivity of Testicular Germ Cell Tumors Is Determined by High Constitutive Noxa Levels Mediated by Oct-4
GUTEKUNST, Matthias, MUELLER, Thomas, WEILBACHER, Andrea, DENGLER, Michael A, BEDKE, Jens, KRUCK, Stephan, OREN, Moshe, AULITZKY, Walter E, VAN DER KUIP, Heiko
Published in Cancer research (Chicago, Ill.) (01.03.2013)
Published in Cancer research (Chicago, Ill.) (01.03.2013)
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Journal Article
An analysis of the role of follicular lymphoma-associated fibroblasts to promote tumor cell viability following drug-induced apoptosis
Staiger, Annette M., Duppel, Jasmin, Dengler, Michael A., van der Kuip, Heiko, Vöhringer, Matthias C., Aulitzky, Walter E., Rosenwald, Andreas, Ott, German, Horn, Heike
Published in Leukemia & lymphoma (03.08.2017)
Published in Leukemia & lymphoma (03.08.2017)
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Journal Article
The role of micro-inflammation in the pathogenesis of uraemic pruritus in haemodialysis patients
Kimmel, Martin, Alscher, Dominik Mark, Dunst, Robert, Braun, Niko, Machleidt, Christoph, Kiefer, Thomas, Stülten, Christina, van der Kuip, Heiko, Pauli-Magnus, Christiane, Raub, Ulrich, Kuhlmann, Ulrich, Mettang, Thomas
Published in Nephrology, dialysis, transplantation (01.03.2006)
Published in Nephrology, dialysis, transplantation (01.03.2006)
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Cytokeratin-18 Is a Useful Serum Biomarker for Early Determination of Response of Breast Carcinomas to Chemotherapy
HÄGG OLOFSSON, Maria, UENO, Takayuki, ANDERSSON, Elina, SHOSHAN, Maria C, MANDIC HAVELKA, Aleksandra, TOI, Masakazu, LINDER, Stig, YANG PAN, REN XU, FENG CAI, VAN DER KUIP, Heiko, MUERDTER, Thomas E, SONNENBERG, Maike, AULITZKY, Walter E, SCHWARZ, Stephan
Published in Clinical cancer research (01.06.2007)
Published in Clinical cancer research (01.06.2007)
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Inhibition of bcr-abl gene expression by small interfering RNA sensitizes for imatinib mesylate (STI571)
Wohlbold, Lara, van der Kuip, Heiko, Miething, Cornelius, Vornlocher, Hans-Peter, Knabbe, Cornelius, Duyster, Justus, Aulitzky, Walter E.
Published in Blood (15.09.2003)
Published in Blood (15.09.2003)
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Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters
Glaeser, Hartmut, Drescher, Siegfried, van der Kuip, Heiko, Behrens, Christoph, Geick, Anke, Burk, Oliver, Dent, John, Somogyi, Andrew, Von Richter, Oliver, Griese, Ernst-Ulrich, Eichelbaum, Michel, Fromm, Martin F
Published in Clinical pharmacology and therapeutics (01.03.2002)
Published in Clinical pharmacology and therapeutics (01.03.2002)
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Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features
Arandkar, Sharathchandra, Furth, Noa, Elisha, Yair, Nataraj, Nishanth Belugali, van der Kuip, Heiko, Yarden, Yosef, Aulitzky, Walter, Ulitsky, Igor, Geiger, Benjamin, Oren, Moshe
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2018)
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