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A novel, efficient and seamless Phase 2A‐2B design to test varoglutamstat in early AD: the VIVA‐MIND study
Messer, Karen, Jacobs, Diane M., Salmon, David P., Qiu, Yuqi, Revta, Carolyn, Weber, Frank, Kuhn‐Wache, Kerstin, Leger, Gabriel C., Feldman, Howard H.
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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A phase 1 study to evaluate the safety and pharmacokinetics of PQ912, a glutaminyl cyclase inhibitor, in healthy subjects
Lues, Inge, Weber, Frank, Meyer, Antje, Bühring, Uli, Hoffmann, Torsten, Kühn-Wache, Kerstin, Manhart, Susanne, Heiser, Ulrich, Pokorny, Rolf, Chiesa, Joseph, Glund, Konrad
Published in Alzheimer's & dementia : translational research & clinical interventions (01.11.2015)
Published in Alzheimer's & dementia : translational research & clinical interventions (01.11.2015)
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On Combination Therapy of Diabetes With Metformin and Dipeptidyl Peptidase IV Inhibitors
Hinke, Simon A., McIntosh, Christopher H. S., Hoffmann, Torsten, Kühn-Wache, Kerstin, Wagner, Leona, Bär, Joachim, Manhart, Susanne, Wermann, Michael, Pederson, Raymond A., Demuth, Hans-Ulrich
Published in Diabetes care (01.08.2002)
Published in Diabetes care (01.08.2002)
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Dipeptidyl Peptidase IV Degradation of Glucagon: Characterization of Glucagon Degradation Products and DPIV Resistant Analogs
HINKE, SIMON A, POSPISILIK, JOHN A, DEMUTH, HANS U, MANNHART, SUSANNE, KUHN-WACHE, KERSTIN, HOFFMANN, TORSTEN, PEDERSON, RAYMOND A, MCINTOSH, CHRISTOPHER H.S
Published in Diabetes (New York, N.Y.) (01.05.2000)
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Published in Diabetes (New York, N.Y.) (01.05.2000)
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Metformin Effects on Dipeptidylpeptidase IV Degradation of Glucagon-like Peptide-1
Hinke, Simon A., Kühn-Wache, Kerstin, Hoffmann, Torsten, Pederson, Raymond A., McIntosh, Christopher H.S., Demuth, Hans-Ulrich
Published in Biochemical and biophysical research communications (15.03.2002)
Published in Biochemical and biophysical research communications (15.03.2002)
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Dipeptidyl peptidase IV (DPIV/CD26) degradation of glucagon. Characterization of glucagon degradation products and DPIV-resistant analogs
Hinke, S A, Pospisilik, J A, Demuth, H U, Mannhart, S, Kühn-Wache, K, Hoffmann, T, Nishimura, E, Pederson, R A, McIntosh, C H
Published in The Journal of biological chemistry (11.02.2000)
Published in The Journal of biological chemistry (11.02.2000)
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[Ser2]- and [SerP2] incretin analogs: comparison of dipeptidyl peptidase IV resistance and biological activities in vitro and in vivo
Hinke, Simon A, Manhart, Susanne, Kühn-Wache, Kerstin, Nian, Cuilan, Demuth, Hans-Ulrich, Pederson, Raymond A, McIntosh, Christopher H S
Published in The Journal of biological chemistry (06.02.2004)
Published in The Journal of biological chemistry (06.02.2004)
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Ser2- and SerP2 incretin analogs: comparison of dipeptidyl peptidase IV resistance and biological activities in vitro and in vivo
Hinke, Simon A, Manhart, Susanne, Kühn-Wache, Kerstin, Nian, Cuilan, Demuth, Hans-Ulrich, Pederson, Raymond A, McIntosh, Christopher H S
Published in The Journal of biological chemistry (06.02.2004)
Published in The Journal of biological chemistry (06.02.2004)
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INHIBIDORES DE LA DIPEPTIDIL-PEPTIDASA IV PARA DISMINUCION DE LA TASA DE AUMENTO CRONICO DE PESO
DEMUTH, HANS-ULRICH, GLUND, KONRAD, KUHN-WACHE, KERSTIN, POSPISILIK, ANDREW J
Year of Publication 16.11.2008
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Year of Publication 16.11.2008
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DIPEPTIDYL PEPTIDASE IV INHIBITORS FOR DECREASING THE RATE OF CHRONIC WEIGHT GAIN
GLUND KONRAD, KUHN-WACHE KERSTIN, POSPISILIK ANDREW J, DEMUTH HANS-ULRICH
Year of Publication 31.10.2008
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Year of Publication 31.10.2008
Patent
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Structure-Activity Relationships of Glucose-Dependent Insulinotropic Polypeptide (GIP)
Hinke, S.A., Gelling, R., Manhart, S., Lynn, F., Pederson, R.A., Kühn-Wache, K., Rosche, F., Demuth, H.-U., Coy, D., McIntosh, C.H.S.
Published in Biological chemistry (01.03.2003)
Published in Biological chemistry (01.03.2003)
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Secondary binding site of dipeptidyl peptidase IV (DP IV)
KUHN-WACHE KERSTIN, BRANDT WOLFGANG, HEISER ULRICH, HOFMANN TORSTEN, BAR JOACHIM, DEMUTH HANS-ULRICH
Year of Publication 19.10.2006
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Year of Publication 19.10.2006
Patent
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Method for raising the blood glucose level in mammals
Demuth, Hans-Ulrich, Hoffmann, Torsten, Kuhn-Wache, Kerstin, Rosche, Fred
Year of Publication 13.06.2002
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Year of Publication 13.06.2002
Patent
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Method for raising the blood glucose level in mammals
HOFFMANN TORSTEN, ROSCHE FRED, KUHN-WACHE KERSTIN, DEMUTH HANS-ULRICH
Year of Publication 13.06.2002
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Year of Publication 13.06.2002
Patent
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Raising blood sugar level in hypoglycemic mammals by administering inhibitors of dipeptidyl peptidase IV
HOFFMANN TORSTEN, ROSCHE FRED, KUHN-WACHE KERSTIN, DEMUTH HANS-ULRICH
Year of Publication 20.11.2001
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Year of Publication 20.11.2001
Patent
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Secondary binding site of dipeptidyl peptidase IV (DPIV)
HOFFMANN TORSTEN, KUHN-WACHE KERSTIN, BRANDT WOLFGANG, HEISER ULRICH, BAR JOACHIM, DEMUTH HANS-ULRICH
Year of Publication 11.08.2005
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Year of Publication 11.08.2005
Patent
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[Ser2]- and [Ser(P)2]Incretin Analogs
Hinke, Simon A., Manhart, Susanne, Kühn-Wache, Kerstin, Nian, Cuilan, Demuth, Hans-Ulrich, Pederson, Raymond A., McIntosh, Christopher H.S.
Published in The Journal of biological chemistry (06.02.2004)
Published in The Journal of biological chemistry (06.02.2004)
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METHODS FOR IMPROVING ISLET SIGNALING IN DIABETES MELLITUS AND FOR ITS PREVENTION
HANS-ULRICH DEMUTH, ANDREW, J. POSPISILIK, KONRAD GLUND, KERSTIN KUHN-WACHE
Year of Publication 11.03.2004
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Year of Publication 11.03.2004
Patent