Whole-body imaging with single-cell resolution by tissue decolorization
Tainaka, Kazuki, Kubota, Shimpei I, Suyama, Takeru Q, Susaki, Etsuo A, Perrin, Dimitri, Ukai-Tadenuma, Maki, Ukai, Hideki, Ueda, Hiroki R
Published in Cell (06.11.2014)
Published in Cell (06.11.2014)
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Journal Article
Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution
Kubota, Shimpei I., Takahashi, Kei, Nishida, Jun, Morishita, Yasuyuki, Ehata, Shogo, Tainaka, Kazuki, Miyazono, Kohei, Ueda, Hiroki R.
Published in Cell reports (Cambridge) (05.07.2017)
Published in Cell reports (Cambridge) (05.07.2017)
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Journal Article
An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis
Takahashi, Kei, Abe, Ko, Kubota, Shimpei I, Fukatsu, Noriaki, Morishita, Yasuyuki, Yoshimatsu, Yasuhiro, Hirakawa, Satoshi, Kubota, Yoshiaki, Watabe, Tetsuro, Ehata, Shogo, Ueda, Hiroki R, Shimamura, Teppei, Miyazono, Kohei
Published in Nature communications (12.09.2022)
Published in Nature communications (12.09.2022)
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Journal Article
GGT1 is a SNP eQTL gene involved in STAT3 activation and associated with the development of Post-ERCP pancreatitis
Furukawa, Ryutaro, Kuwatani, Masaki, Jiang, Jing-Jing, Tanaka, Yuki, Hasebe, Rie, Murakami, Kaoru, Tanaka, Kumiko, Hirata, Noriyuki, Ohki, Izuru, Takahashi, Ikuko, Yamasaki, Takeshi, Shinohara, Yuta, Nozawa, Shunichiro, Hojyo, Shintaro, Kubota, Shimpei I, Hashimoto, Shigeru, Hirano, Satoshi, Sakamoto, Naoya, Murakami, Masaaki
Published in Scientific reports (28.05.2024)
Published in Scientific reports (28.05.2024)
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Journal Article
Dupuytren’s contracture-associated SNPs increase SFRP4 expression in non-immune cells including fibroblasts to enhance inflammation development
Kida, Hiroaki, Jiang, Jing-Jing, Matsui, Yuichiro, Takahashi, Ikuko, Hasebe, Rie, Kawamura, Daisuke, Endo, Takeshi, Shibayama, Hiroki, Kondo, Makoto, Nishio, Yasuhiko, Nishida, Kinya, Matsuno, Yoshihiro, Oikawa, Tsukasa, Kubota, Shimpei I, Hojyo, Shintaro, Iwasaki, Norimasa, Hashimoto, Shigeru, Tanaka, Yuki, Murakami, Masaaki
Published in International immunology (07.07.2023)
Published in International immunology (07.07.2023)
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Journal Article
Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study
Zhai, Tianyue, Mitamura, Takashi, Wang, Lei, Kubota, Shimpei I., Murakami, Masaaki, Tanaka, Shinya, Watari, Hidemichi
Published in Cancer medicine (Malden, MA) (01.04.2023)
Published in Cancer medicine (Malden, MA) (01.04.2023)
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Journal Article
Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing
Takahashi, Kei, Kubota, Shimpei I., Ehata, Shogo, Ueda, Hiroki R., Miyazono, Kohei
Published in STAR protocols (18.12.2020)
Published in STAR protocols (18.12.2020)
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Journal Article
Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing
Kubota, Shimpei I, Takahashi, Kei, Mano, Tomoyuki, Matsumoto, Katsuhiko, Katsumata, Takahiro, Shi, Shoi, Tainaka, Kazuki, Ueda, Hiroki R, Ehata, Shogo, Miyazono, Kohei
Published in Communications biology (05.03.2021)
Published in Communications biology (05.03.2021)
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Journal Article
Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an Activatable Covalent Fluorescent Probe Compatible with Tissue Clearing
Sakamoto, Daichi M., Tamura, Iori, Yi, Bo, Hasegawa, Sho, Saito, Yutaro, Yamada, Naoki, Takakusagi, Yoichi, Kubota, Shimpei I., Kobayashi, Minoru, Harada, Hiroshi, Hanaoka, Kenjiro, Taki, Masayasu, Nangaku, Masaomi, Tainaka, Kazuki, Sando, Shinsuke
Published in ACS nano (13.02.2024)
Published in ACS nano (13.02.2024)
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Journal Article
Calcineurin inhibitor inhibits tolerance induction by suppressing terminal exhaustion of donor T cells after allo-HCT
Senjo, Hajime, Harada, Shinpei, Kubota, Shimpei I., Tanaka, Yuki, Tateno, Takahiro, Zhang, Zixuan, Okada, Satomi, Chen, Xuanzhong, Kikuchi, Ryo, Miyashita, Naoki, Onozawa, Masahiro, Goto, Hideki, Endo, Tomoyuki, Hasegawa, Yuta, Ohigashi, Hiroyuki, Ara, Takahide, Hasegawa, Yoshinori, Murakami, Masaaki, Teshima, Takanori, Hashimoto, Daigo
Published in Blood (03.08.2023)
Published in Blood (03.08.2023)
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Journal Article
DDX6 is involved in the pathogenesis of inflammatory diseases via NF-κB activation
Naito, Seiichiro, Tanaka, Hiroki, Jiang, Jing-Jing, Tarumi, Masato, Hashimoto, Ari, Tanaka, Yuki, Murakami, Kaoru, Kubota, Shimpei I., Hojyo, Shintaro, Hashimoto, Shigeru, Murakami, Masaaki
Published in Biochemical and biophysical research communications (09.04.2024)
Published in Biochemical and biophysical research communications (09.04.2024)
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Journal Article
A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues
Glaser, Adam K, Bishop, Kevin W, Barner, Lindsey A, Susaki, Etsuo A, Kubota, Shimpei I, Gao, Gan, Serafin, Robert B, Balaram, Pooja, Turschak, Emily, Nicovich, Philip R, Lai, Hoyin, Lucas, Luciano A G, Yi, Yating, Nichols, Eva K, Huang, Hongyi, Reder, Nicholas P, Wilson, Jasmine J, Sivakumar, Ramya, Shamskhou, Elya, Stoltzfus, Caleb R, Wei, Xing, Hempton, Andrew K, Pende, Marko, Murawala, Prayag, Dodt, Hans-Ulrich, Imaizumi, Takato, Shendure, Jay, Beliveau, Brian J, Gerner, Michael Y, Xin, Li, Zhao, Hu, True, Lawrence D, Reid, R Clay, Chandrashekar, Jayaram, Ueda, Hiroki R, Svoboda, Karel, Liu, Jonathan T C
Published in Nature methods (01.05.2022)
Published in Nature methods (01.05.2022)
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Journal Article
GM-CSF Promotes the Survival of Peripheral-Derived Myeloid Cells in the Central Nervous System for Pain-Induced Relapse of Neuroinflammation
Matsuyama, Shiina, Yamamoto, Reiji, Murakami, Kaoru, Takahashi, Nobuhiko, Nishi, Rieko, Ishii, Asuka, Nio-Kobayashi, Junko, Abe, Nobuya, Tanaka, Kumiko, Jiang, Jing-Jing, Kawamoto, Tadafumi, Iwanaga, Toshihiko, Shinohara, Yuta, Yamasaki, Takeshi, Ohki, Izuru, Hojyo, Shintaro, Hasebe, Rie, Kubota, Shimpei I, Hirata, Noriyuki, Kamimura, Daisuke, Hashimoto, Shigeru, Tanaka, Yuki, Murakami, Masaaki
Published in The Journal of immunology (1950) (01.07.2023)
Published in The Journal of immunology (1950) (01.07.2023)
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Journal Article
High-precision rapid testing of omicron SARS-CoV-2 variants in clinical samples using AI-nanopore
Murakami, Kaoru, Kubota, Shimpei I, Tanaka, Kumiko, Tanaka, Hiroki, Akabane, Keiichiroh, Suzuki, Rigel, Shinohara, Yuta, Takei, Hiroyasu, Hashimoto, Shigeru, Tanaka, Yuki, Hojyo, Shintaro, Sakamoto, Osamu, Naono, Norihiko, Takaai, Takayui, Sato, Kazuki, Kojima, Yuichi, Harada, Toshiyuki, Hattori, Takeshi, Fuke, Satoshi, Yokota, Isao, Konno, Satoshi, Washio, Takashi, Fukuhara, Takasuke, Teshima, Takanori, Taniguchi, Masateru, Murakami, Masaaki
Published in Lab on a chip (07.11.2023)
Published in Lab on a chip (07.11.2023)
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Journal Article
Computer model of IL-6-dependent rheumatoid arthritis in F759 mice
Yamamoto, Reiji, Yamada, Satoshi, Atsumi, Toru, Murakami, Kaoru, Hashimoto, Ari, Naito, Seiichiro, Tanaka, Yuki, Ohki, Izuru, Shinohara, Yuta, Iwasaki, Norimasa, Yoshimura, Akihiko, Jiang, Jing-Jing, Kamimura, Daisuke, Hojyo, Shintaro, Kubota, Shimpei I, Hashimoto, Shigeru, Murakami, Masaaki
Published in International immunology (05.09.2023)
Published in International immunology (05.09.2023)
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Journal Article
Click3D: Click reaction across deep tissues for whole-organ 3D fluorescence imaging
Tamura, Iori, Sakamoto, Daichi M., Yi, Bo, Saito, Yutaro, Yamada, Naoki, Morimoto, Jumpei, Takakusagi, Yoichi, Kuroda, Masafumi, Kubota, Shimpei I., Yatabe, Hiroyuki, Kobayashi, Minoru, Harada, Hiroshi, Tainaka, Kazuki, Sando, Shinsuke
Published in Science advances (19.07.2024)
Published in Science advances (19.07.2024)
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Journal Article
In situ Microinflammation Detection Using Gold Nanoclusters and a Tissue-clearing Method
Naim, Fayrouz, Hasebe, Rie, Hojyo, Shintaro, Shichibu, Yukatsu, Ishii, Asuka, Tanaka, Yuki, Tainaka, Kazuki, Kubota, Shimpei I, Konishi, Katsuaki, Murakami, Masaaki
Published in Bio-protocol (05.04.2023)
Published in Bio-protocol (05.04.2023)
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Journal Article