Structural and Biochemical Characterization of an Active Arylamine N-Acetyltransferase Possessing a Non-canonical Cys-His-Glu Catalytic Triad
Kubiak, Xavier, Li de la Sierra-Gallay, Inès, Chaffotte, Alain F., Pluvinage, Benjamin, Weber, Patrick, Haouz, Ahmed, Dupret, Jean-Marie, Rodrigues-Lima, Fernando
Published in The Journal of biological chemistry (02.08.2013)
Published in The Journal of biological chemistry (02.08.2013)
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Journal Article
Assembly of a GPCR-G Protein Complex
Du, Yang, Duc, Nguyen Minh, Rasmussen, Søren G.F., Hilger, Daniel, Kubiak, Xavier, Wang, Liwen, Bohon, Jennifer, Kim, Hee Ryung, Wegrecki, Marcin, Asuru, Awuri, Jeong, Kyung Min, Lee, Jeongmi, Chance, Mark R., Lodowski, David T., Kobilka, Brian K., Chung, Ka Young
Published in Cell (16.05.2019)
Published in Cell (16.05.2019)
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Journal Article
Ruminococcin C, an anti-clostridial sactipeptide produced by a prominent member of the human microbiota Ruminococcus gnavus
Balty, Clémence, Guillot, Alain, Fradale, Laura, Brewee, Clémence, Boulay, Mylène, Kubiak, Xavier, Benjdia, Alhosna, Berteau, Olivier
Published in The Journal of biological chemistry (04.10.2019)
Published in The Journal of biological chemistry (04.10.2019)
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Journal Article
Exploring the Biosynthetic Potential of TsrM, a B12‐dependent Radical SAM Methyltransferase Catalyzing Non‐radical Reactions
Soualmia, Feryel, Guillot, Alain, Sabat, Nazarii, Brewee, Clémence, Kubiak, Xavier, Haumann, Michael, Guinchard, Xavier, Benjdia, Alhosna, Berteau, Olivier
Published in Chemistry : a European journal (01.06.2022)
Published in Chemistry : a European journal (01.06.2022)
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Journal Article
Exploring the Biosynthetic Potential of TsrM, a B 12 -dependent Radical SAM Methyltransferase Catalyzing Non-radical Reactions
Soualmia, Feryel, Guillot, Alain, Sabat, Nazarii, Brewee, Clémence, Kubiak, Xavier, Haumann, Michael, Guinchard, Xavier, Benjdia, Alhosna, Berteau, Olivier
Published in Chemistry : a European journal (01.06.2022)
Published in Chemistry : a European journal (01.06.2022)
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Journal Article
Exploring the biosynthetic capacity of TsrM, a B12‐dependent Radical SAM Enzyme Catalyzing Non‐radical Reactions
Soualmia, Feryel, Guillot, Alain, Sabat, Nazarii, Brewee, Clémence, Kubiak, Xavier, Haumann, Michael, Guinchard, Xavier, Benjdia, Alhosna, Berteau, Olivier
Published in Chemistry : a European journal (01.03.2022)
Published in Chemistry : a European journal (01.03.2022)
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Journal Article
Mechanistic Investigations of PoyD, a Radical S‑Adenosyl‑l‑methionine Enzyme Catalyzing Iterative and Directional Epimerizations in Polytheonamide A Biosynthesis
Parent, Aubérie, Benjdia, Alhosna, Guillot, Alain, Kubiak, Xavier, Balty, Clémence, Lefranc, Benjamin, Leprince, Jérôme, Berteau, Olivier
Published in Journal of the American Chemical Society (21.02.2018)
Published in Journal of the American Chemical Society (21.02.2018)
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Journal Article
Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme
Kubiak, Xavier, Polsinelli, Ivan, Chavas, Leonard M. G., Fyfe, Cameron D., Guillot, Alain, Fradale, Laura, Brewee, Clémence, Grimaldi, Stéphane, Gerbaud, Guillaume, Thureau, Aurélien, Legrand, Pierre, Berteau, Olivier, Benjdia, Alhosna
Published in Nature chemical biology (01.03.2024)
Published in Nature chemical biology (01.03.2024)
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Journal Article
Insights into the catalysis of a lysine-tryptophan bond in bacterial peptides by a SPASM domain radical S-adenosylmethionine (SAM) peptide cyclase
Benjdia, Alhosna, Decamps, Laure, Guillot, Alain, Kubiak, Xavier, Ruffié, Pauline, Sandström, Corine, Berteau, Olivier
Published in The Journal of biological chemistry (30.06.2017)
Published in The Journal of biological chemistry (30.06.2017)
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Journal Article
Assembly of a GPCR-G Protein Complex
Du, Yang, Duc, Nguyen Minh, Rasmussen, Søren G. F., Hilger, Daniel, Kubiak, Xavier, Wang, Liwen, Bohon, Jennifer, Kim, Hee Ryung, Wegrecki, Marcin, Asuru, Awuri, Jeong, Kyung Min, Lee, Jeongmi, Chance, Mark R., Lodowski, David T., Kobilka, Brian K., Chung, Ka Young
Published in Cell (01.05.2019)
Published in Cell (01.05.2019)
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Journal Article
Xenobiotic‐metabolizing enzymes in Bacillus anthracis: molecular and functional analysis of a truncated arylamine N‐acetyltransferase isozyme
Kubiak, Xavier, Duval, Romain, Pluvinage, Benjamin, Chaffotte, Alain F, Dupret, Jean‐Marie, Rodrigues‐Lima, Fernando
Published in British journal of pharmacology (01.07.2017)
Published in British journal of pharmacology (01.07.2017)
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Journal Article
Time-resolved Conformational Analysis during GPCR-Gs Coupling
Published in 日本薬理学会年会要旨集
(2020)
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Journal Article
Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor
Boyhus, Lotte-Emilie, Danielsen, Mia, Nina Smidt Bengtson, Micha Ben Achim Kunze, Kubiak, Xavier, Sminia, Tjerk J, Jacob Hartvig Løper, Tran, Phuong Thu, Lindorff-Larsen, Kresten, Rasmussen, Søren G F, Mathiesen, Jesper Mosolff, Pedersen, Daniel Sejer
Published in RSC advances (2018)
Published in RSC advances (2018)
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Journal Article
Crystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity
Kubiak, Xavier, Dairou, Julien, Dupret, Jean-Marie, Rodrigues-Lima, Fernando
Published in Expert opinion on drug metabolism & toxicology (01.03.2013)
Published in Expert opinion on drug metabolism & toxicology (01.03.2013)
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Journal Article
G s protein peptidomimetics as allosteric modulators of the β 2 -adrenergic receptor
Boyhus, Lotte-Emilie, Danielsen, Mia, Bengtson, Nina Smidt, Ben Achim Kunze, Micha, Kubiak, Xavier, Sminia, Tjerk J, Løper, Jacob Hartvig, Tran, Phuong Thu, Lindorff-Larsen, Kresten, Rasmussen, Søren G F, Mathiesen, Jesper Mosolff, Pedersen, Daniel Sejer
Published in RSC advances (09.01.2018)
Published in RSC advances (09.01.2018)
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Journal Article
Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A
Xu, Ximing, Li de la Sierra-Gallay, Inés, Kubiak, Xavier, Duval, Romain, Chaffotte, Alain F., Dupret, Jean-Marie, Haouz, Ahmed, Rodrigues-Lima, Fernando
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2015)
Published in Acta crystallographica. Section D, Biological crystallography. (01.02.2015)
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Journal Article
Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition
Cocaign, Angélique, Kubiak, Xavier, Xu, Ximing, Garnier, Guillaume, Li de la Sierra-Gallay, Inès, Chi-Bui, Linh, Dairou, Julien, Busi, Florent, Abuhammad, Areej, Haouz, Ahmed, Dupret, Jean-Marie, Herrmann, Jean-Louis, Rodrigues-Lima, Fernando
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2014)
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2014)
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Journal Article