N-Nitrosation in the absence of nitrosating agents in pharmaceuticals?
Jireš, Jakub, Douša, Michal, Gibala, Petr, Kubelka, Tomáš
Published in Journal of pharmaceutical and biomedical analysis (05.09.2022)
Published in Journal of pharmaceutical and biomedical analysis (05.09.2022)
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Journal Article
Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly
Jagtap, Pravin Kumar Ankush, Kubelka, Tomáš, Soni, Komal, Will, Cindy L., Garg, Divita, Sippel, Claudia, Kapp, Tobias G., Potukuchi, Harish Kumar, Schorpp, Kenji, Hadian, Kamyar, Kessler, Horst, Lührmann, Reinhard, Hausch, Felix, Bach, Thorsten, Sattler, Michael
Published in Nature communications (06.11.2020)
Published in Nature communications (06.11.2020)
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Journal Article
Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet
Dhami, Kirandeep, Malyshev, Denis A, Ordoukhanian, Phillip, Kubelka, Tomáš, Hocek, Michal, Romesberg, Floyd E
Published in Nucleic acids research (15.09.2014)
Published in Nucleic acids research (15.09.2014)
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Journal Article
Parameter optimization in a continuous direct compression process of commercially batch-produced bisoprolol tablets
Lyytikäinen, Jenna, Stasiak, Pawel, Kubelka, Tomáš, Olenius, Tino, Korhonen, Ossi, Ketolainen, Jarkko, Ervasti, Tuomas
Published in International journal of pharmaceutics (25.11.2022)
Published in International journal of pharmaceutics (25.11.2022)
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Journal Article
Manufacturing process transfer to a 30 kg/h continuous direct compression line with real-time composition monitoring
Waněk, Adam, Menarini, Lorenzo, Giatti, Federica, Kubelka, Tomáš, Consoli, Fabrizio, Funaro, Caterina, Stasiak, Pawel, Štěpánek, František
Published in International journal of pharmaceutics (10.05.2024)
Published in International journal of pharmaceutics (10.05.2024)
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Journal Article
Continuous direct compression of a commercially batch-manufactured tablet formulation with two different processing lines
Lyytikäinen, Jenna, Stasiak, Pawel, Kubelka, Tomáš, Bogaerts, Ivan, Wanek, Adam, Stynen, Bart, Holman, James, Ketolainen, Jarkko, Ervasti, Tuomas, Korhonen, Ossi
Published in European journal of pharmaceutics and biopharmaceutics (01.06.2024)
Published in European journal of pharmaceutics and biopharmaceutics (01.06.2024)
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Journal Article
Insight into the formation of N-nitrosodimethylamine in metformin products
Jireš, Jakub, Kalášek, Stanislav, Gibala, Petr, Rudovský, Jakub, Douša, Michal, Kubelka, Tomáš, Hrubý, Jan, Řezanka, Pavel
Published in Journal of pharmaceutical and biomedical analysis (20.02.2021)
Published in Journal of pharmaceutical and biomedical analysis (20.02.2021)
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Journal Article
HPLC/UV/MS method application for the separation of obeticholic acid and its related compounds in development process and quality control
Douša, Michal, Slavíková, Markéta, Kubelka, Tomáš, Černý, Josef, Gibala, Petr, Zezula, Josef
Published in Journal of pharmaceutical and biomedical analysis (05.02.2018)
Published in Journal of pharmaceutical and biomedical analysis (05.02.2018)
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Journal Article
Inhibition of CPAP–tubulin interaction prevents proliferation of centrosome‐amplified cancer cells
Mariappan, Aruljothi, Soni, Komal, Schorpp, Kenji, Zhao, Fan, Minakar, Amin, Zheng, Xiangdong, Mandad, Sunit, Macheleidt, Iris, Ramani, Anand, Kubelka, Tomáš, Dawidowski, Maciej, Golfmann, Kristina, Wason, Arpit, Yang, Chunhua, Simons, Judith, Schmalz, Hans‐Günther, Hyman, Anthony A, Aneja, Ritu, Ullrich, Roland, Urlaub, Henning, Odenthal, Margarete, Büttner, Reinhardt, Li, Haitao, Sattler, Michael, Hadian, Kamyar, Gopalakrishnan, Jay
Published in The EMBO journal (15.01.2019)
Published in The EMBO journal (15.01.2019)
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Journal Article
Incidence of Hospitalized Stroke in the Czech Republic: The National Registry of Hospitalized Patients
Sedova, Petra, MD, Brown, Robert D., MD, MPH, Zvolsky, Miroslav, MD, Kadlecova, Pavla, PhD, Bryndziar, Tomas, MD, Kubelka, Tomáš, MD, Weiss, Viktor, MD, Volný, Ondřej, MD, Bednarik, Josef, MD, PhD, Mikulik, Robert, MD, PhD
Published in Journal of stroke and cerebrovascular diseases (01.05.2017)
Published in Journal of stroke and cerebrovascular diseases (01.05.2017)
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Journal Article
Synthesis of 2,6-disubstituted pyridin-3-yl C-2 '-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides
Kubelka, Tomas, Slavetinska, Lenka, Eigner, Vaclav, Hocek, Michal
Published in Organic & biomolecular chemistry (28.07.2013)
Published in Organic & biomolecular chemistry (28.07.2013)
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Journal Article
Synthesis of 2,4-Disubstituted Pyrimidin-5-yl C-2′-Deoxyribonucleosides by Sequential Regioselective Reactions of 2,4-Dichloropyrimidine Nucleosides
Kubelka, Tomáš, Slavětínská, Lenka, Klepetářová, Blanka, Hocek, Michal
Published in European Journal of Organic Chemistry (01.05.2010)
Published in European Journal of Organic Chemistry (01.05.2010)
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Book Review
Journal Article
Synthesis of 6-Substituted 2(1H)-Pyridon-3-yl C-2′-Deoxyribonucleosides
Chapuis, Hubert, Kubelka, Tomáš, Joubert, Nicolas, Pohl, Radek, Hocek, Michal
Published in European Journal of Organic Chemistry (01.03.2012)
Published in European Journal of Organic Chemistry (01.03.2012)
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Book Review
Journal Article
Challenges encountered in the transfer of atorvastatin tablet manufacturing - commercial batch-based production as a basis for small-scale continuous tablet manufacturing tests
Lyytikäinen, Jenna, Kyllönen, Saini, Ervasti, Tuomas, Komulainen, Eelis, Pekarek, Tomáš, Slunečková, Jitka, Leskinen, Jari, Ketolainen, Jarkko, Kubelka, Tomáš, Stasiak, Pawel, Korhonen, Ossi
Published in International journal of pharmaceutics (25.11.2023)
Published in International journal of pharmaceutics (25.11.2023)
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Journal Article
Synthesis of 2,4-Disubstituted Pyrimidin-5-yl G2'-Deoxyribonucleosides by Sequential Regioselective Reactions of 2,4-Dichloropyrimidine Nucleosides
KUBELKA, Tomáš, SIAVETINSKA, Lenka, KLEPETAROVA, Blanka, HOCEK, Michal
Published in European journal of organic chemistry (2010)
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Published in European journal of organic chemistry (2010)
Journal Article