Metformin doses to ensure efficacy and safety in patients with reduced kidney function
Kuan, Isabelle H S, Wilson, Luke C, Leishman, Jed C, Cosgrove, Samuel, Walker, Robert J, Putt, Tracey L, Schollum, John B W, Wright, Daniel F B
Published in PloS one (18.02.2021)
Published in PloS one (18.02.2021)
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Journal Article
The Association between Metformin Therapy and Lactic Acidosis
Kuan, Isabelle H. S., Savage, Ruth L., Duffull, Stephen B., Walker, Robert J., Wright, Daniel F. B.
Published in Drug safety (01.12.2019)
Published in Drug safety (01.12.2019)
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Journal Article
The influence of flip‐flop in population pharmacokinetic analyses
Kuan, Isabelle H. S., Wright, Daniel F. B., Duffull, Stephen B.
Published in CPT: pharmacometrics and systems pharmacology (01.03.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.03.2023)
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Journal Article
Understanding the association between metformin plasma concentrations and lactate
Kuan, Isabelle H.S., Wright, Daniel F.B., Duffull, Stephen B., Zhu, Xiao
Published in British journal of clinical pharmacology (01.02.2021)
Published in British journal of clinical pharmacology (01.02.2021)
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Journal Article
Does the intact nephron hypothesis provide a reasonable model for metformin dosing in chronic kidney disease?
Pradhan, Sudeep, Duffull, Stephen B., Wilson, Luke C., Kuan, Isabelle H. S., Walker, Robert J., Putt, Tracey L., Schollum, John B. W., Wright, Daniel F. B.
Published in British journal of clinical pharmacology (01.12.2021)
Published in British journal of clinical pharmacology (01.12.2021)
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Journal Article
Model-Informed Drug Development, Pharmacokinetic/Pharmacodynamic Cutoff Value Determination, and Antibacterial Efficacy of Benapenem against Enterobacteriaceae
Ji, Xi-Wei, Xue, Feng, Kang, Zi-Sheng, Zhong, Wei, Kuan, Isabelle Hui-San, Yang, Xi-Ping, Zhu, Xiao, Li, Yun, Lv, Yuan
Published in Antimicrobial agents and chemotherapy (21.02.2020)
Published in Antimicrobial agents and chemotherapy (21.02.2020)
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Journal Article
A phase I trial of SON-1010, a tumor-targeted, interleukin-12-linked, albumin-binding cytokine, shows favorable pharmacokinetics, pharmacodynamics, and safety in healthy volunteers
Kenney, Richard T, Cini, John K, Dexter, Susan, DaFonseca, Manuel, Bingham, Justus, Kuan, Isabelle, Chawla, Sant P, Polasek, Thomas M, Lickliter, Jason, Ryan, Philip J
Published in Frontiers in immunology (29.02.2024)
Published in Frontiers in immunology (29.02.2024)
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Journal Article
Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae
Ji, Xi-Wei, Zhu, Xiao, Li, Yun, Xue, Feng, Kuan, Isabelle Hui San, He, Qing-Feng, Meng, Xiang-Rui, Xiang, Xiao-Qiang, Cui, Yi-Min, Zheng, Bo
Published in Frontiers in pharmacology (18.07.2022)
Published in Frontiers in pharmacology (18.07.2022)
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Journal Article
Preliminary Results of a Phase 1 Study in Healthy Subjects Administered Inclacumab, a Fully Human IgG4 Anti-P-Selectin Monoclonal Antibody in Development for Treatment of Sickle Cell Disease
Mayer, Christina, Cooper, Daniel Scott, Redfern, Andrew, Geng, Xin, Shi, Jianxia, van Zutphen-van Geffen, Mariëlle, Kuan, Isabelle, Koeck, Kathleen, Kastrissios, Helen, Patel, Kashyap, Davis, Mark, Yue, Patrick
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
A Population Pharmacokinetic Model for 51 Cr EDTA to Estimate Renal Function
Kuan, Isabelle H S, Duffull, Stephen B, Putt, Tracey L, Schollum, John B W, Walker, Robert J, Wright, Daniel F B
Published in Clinical pharmacokinetics (01.06.2017)
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Published in Clinical pharmacokinetics (01.06.2017)
Journal Article