Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases
Veillard, Florian, Sztukowska, Maryta, Mizgalska, Danuta, Ksiazek, Mirosław, Houston, John, Potempa, Barbara, Enghild, Jan J., Thogersen, Ida B., Gomis-Rüth, F. Xavier, Nguyen, Ky-Anh, Potempa, Jan
Published in Biochimica et biophysica acta (01.08.2013)
Published in Biochimica et biophysica acta (01.08.2013)
Get full text
Journal Article
Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor
Guevara, Tibisay, Rodríguez-Banqueri, Arturo, Lasica, Anna M, Ksiazek, Miroslaw, Potempa, Barbara A, Potempa, Jan, Gomis-Rüth, F Xavier
Published in Scientific reports (20.03.2019)
Published in Scientific reports (20.03.2019)
Get full text
Journal Article
Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis
Lasica, Anna M, Goulas, Theodoros, Mizgalska, Danuta, Zhou, Xiaoyan, de Diego, Iñaki, Ksiazek, Mirosław, Madej, Mariusz, Guo, Yonghua, Guevara, Tibisay, Nowak, Magdalena, Potempa, Barbara, Goel, Apoorv, Sztukowska, Maryta, Prabhakar, Apurva T, Bzowska, Monika, Widziolek, Magdalena, Thøgersen, Ida B, Enghild, Jan J, Simonian, Mary, Kulczyk, Arkadiusz W, Nguyen, Ky-Anh, Potempa, Jan, Gomis-Rüth, F Xavier
Published in Scientific reports (24.11.2016)
Published in Scientific reports (24.11.2016)
Get full text
Journal Article
Identification and characterization of aptameric inhibitors of human neutrophil elastase
Malicki, Stanisław, Książek, Mirosław, Sochaj Gregorczyk, Alicja, Kamińska, Marta, Golda, Anna, Chruścicka, Barbara, Mizgalska, Danuta, Potempa, Jan, Marti, Hans-Peter, Kozieł, Joanna, Wieczorek, Maciej, Pieczykolan, Jerzy, Mydel, Piotr, Dubin, Grzegorz
Published in The Journal of biological chemistry (01.08.2023)
Published in The Journal of biological chemistry (01.08.2023)
Get full text
Journal Article
Structural and functional insights into the C-terminal signal domain of the Bacteroidetes type-IX secretion system
Mizgalska, Danuta, Rodríguez-Banqueri, Arturo, Veillard, Florian, Książęk, Mirosław, Goulas, Theodoros, Guevara, Tibisay, Eckhard, Ulrich, Potempa, Jan, Gomis-Rüth, F Xavier
Published in Open biology (01.06.2024)
Published in Open biology (01.06.2024)
Get full text
Journal Article
Plasmin inhibition by bacterial serpin: Implications in gum disease
Sochaj-Gregorczyk, Alicja, Ksiazek, Miroslaw, Waligorska, Irena, Straczek, Anna, Benedyk, Malgorzata, Mizgalska, Danuta, Thøgersen, Ida B, Enghild, Jan J, Potempa, Jan
Published in The FASEB journal (01.01.2020)
Published in The FASEB journal (01.01.2020)
Get more information
Journal Article
A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia
Książek, Mirosław, Goulas, Theodoros, Mizgalska, Danuta, Rodríguez-Banqueri, Arturo, Eckhard, Ulrich, Veillard, Florian, Waligórska, Irena, Benedyk-Machaczka, Małgorzata, Sochaj-Gregorczyk, Alicja M, Madej, Mariusz, Thøgersen, Ida B, Enghild, Jan J, Cuppari, Anna, Arolas, Joan L, de Diego, Iñaki, López-Pelegrín, Mar, Garcia-Ferrer, Irene, Guevara, Tibisay, Dive, Vincent, Zani, Marie-Louise, Moreau, Thierry, Potempa, Jan, Gomis-Rüth, F Xavier
Published in Chemical science (Cambridge) (25.01.2023)
Published in Chemical science (Cambridge) (25.01.2023)
Get full text
Journal Article
A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system
Jusko, Monika, Potempa, Jan, Karim, Abdulkarim Y, Ksiazek, Miroslaw, Riesbeck, Kristian, Garred, Peter, Eick, Sigrun, Blom, Anna M
Published in The Journal of immunology (1950) (01.03.2012)
Published in The Journal of immunology (1950) (01.03.2012)
Get full text
Journal Article
Anti-CD44 DNA Aptamers Selectively Target Cancer Cells
Pęcak, Aleksandra, Skalniak, Łukasz, Pels, Katarzyna, Książek, Mirosław, Madej, Mariusz, Krzemień, Dobrosława, Malicki, Stanisław, Władyka, Benedykt, Dubin, Adam, Holak, Tad A, Dubin, Grzegorz
Published in Nucleic acid therapeutics (01.10.2020)
Published in Nucleic acid therapeutics (01.10.2020)
Get more information
Journal Article
PorZ, an Essential Component of the Type IX Secretion System of Porphyromonas gingivalis , Delivers Anionic Lipopolysaccharide to the PorU Sortase for Transpeptidase Processing of T9SS Cargo Proteins
Madej, Mariusz, Nowakowska, Zuzanna, Ksiazek, Miroslaw, Lasica, Anna M, Mizgalska, Danuta, Nowak, Magdalena, Jacula, Anna, Bzowska, Monika, Scavenius, Carsten, Enghild, Jan J, Aduse-Opoku, Joseph, Curtis, Michael A, Gomis-Rüth, F Xavier, Potempa, Jan
Published in mBio (23.02.2021)
Published in mBio (23.02.2021)
Get full text
Journal Article
Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia
Zak, Krzysztof M., Bostock, Mark J., Waligorska, Irena, Thøgersen, Ida B., Enghild, Jan J., Popowicz, Grzegorz M., Grudnik, Przemyslaw, Potempa, Jan, Ksiazek, Miroslaw
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Get full text
Journal Article
Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB
Wichert, Rielana, Ermund, Anna, Schmidt, Stefanie, Schweinlin, Matthias, Ksiazek, Miroslaw, Arnold, Philipp, Knittler, Katharina, Wilkens, Frederike, Potempa, Barbara, Rabe, Björn, Stirnberg, Marit, Lucius, Ralph, Bartsch, Jörg W., Nikolaus, Susanna, Falk-Paulsen, Maren, Rosenstiel, Philip, Metzger, Marco, Rose-John, Stefan, Potempa, Jan, Hansson, Gunnar C., Dempsey, Peter J., Becker-Pauly, Christoph
Published in Cell reports (Cambridge) (21.11.2017)
Published in Cell reports (Cambridge) (21.11.2017)
Get full text
Journal Article
Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase
Staniec, Dominika, Ksiazek, Miroslaw, Thøgersen, Ida B., Enghild, Jan J., Sroka, Aneta, Bryzek, Danuta, Bogyo, Matthew, Abrahamson, Magnus, Potempa, Jan
Published in The Journal of biological chemistry (06.11.2015)
Published in The Journal of biological chemistry (06.11.2015)
Get full text
Journal Article
A phage display selected 7-mer peptide inhibitor of the Tannerella forsythia metalloprotease-like enzyme Karilysin can be truncated to Ser-Trp-Phe-Pro
Skottrup, Peter Durand, Sørensen, Grete, Ksiazek, Miroslaw, Potempa, Jan, Riise, Erik
Published in PloS one (31.10.2012)
Published in PloS one (31.10.2012)
Get full text
Journal Article
Proteolytic Inactivation of LL-37 by Karilysin, a Novel Virulence Mechanism of Tannerella forsythia
Koziel, Joanna, Karim, Aabdulkarim Y., Przybyszewska, Kornelia, Ksiazek, Miroslaw, Rapala-Kozik, Maria, Nguyen, Ky-Anh, Potempa, Jan
Published in Journal of innate immunity (01.01.2010)
Published in Journal of innate immunity (01.01.2010)
Get full text
Journal Article
Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop
Ksiazek, Miroslaw, Mizgalska, Danuta, Enghild, Jan J., Scavenius, Carsten, Thogersen, Ida B., Potempa, Jan
Published in The Journal of biological chemistry (02.01.2015)
Published in The Journal of biological chemistry (02.01.2015)
Get full text
Journal Article