The CDCP1 Signaling Hub: A Target for Cancer Detection and Therapeutic Intervention
Khan, Tashbib, Kryza, Thomas, Lyons, Nicholas J, He, Yaowu, Hooper, John D
Published in Cancer research (Chicago, Ill.) (01.05.2021)
Published in Cancer research (Chicago, Ill.) (01.05.2021)
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GelMA, Click-Chemistry Gelatin and Bioprinted Polyethylene Glycol-Based Hydrogels as 3D Ex Vivo Drug Testing Platforms for Patient-Derived Breast Cancer Organoids
Bock, Nathalie, Forouz, Farzaneh, Hipwood, Luke, Clegg, Julien, Jeffery, Penny, Gough, Madeline, van Wyngaard, Tirsa, Pyke, Christopher, Adams, Mark N, Bray, Laura J, Croft, Laura, Thompson, Erik W, Kryza, Thomas, Meinert, Christoph
Published in Pharmaceutics (12.01.2023)
Published in Pharmaceutics (12.01.2023)
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Journal Article
The molecular function of kallikrein‐related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer
Kryza, Thomas, Bock, Nathalie, Lovell, Scott, Rockstroh, Anja, Lehman, Melanie L., Lesner, Adam, Panchadsaram, Janaththani, Silva, Lakmali Munasinghage, Srinivasan, Srilakshmi, Snell, Cameron E., Williams, Elizabeth D., Fazli, Ladan, Gleave, Martin, Batra, Jyotsna, Nelson, Colleen, Tate, Edward W., Harris, Jonathan, Hooper, John D., Clements, Judith A.
Published in Molecular oncology (01.01.2020)
Published in Molecular oncology (01.01.2020)
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Journal Article
Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency
Silva, Lakmali Munasinghage, Stoll, Thomas, Kryza, Thomas, Stephens, Carson Ryan, Hastie, Marcus Lachlan, Irving-Rodgers, Helen Frances, Dong, Ying, Gorman, Jeffrey John, Clements, Judith Ann
Published in Scientific reports (28.07.2017)
Published in Scientific reports (28.07.2017)
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Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma
Khan, Tashbib, He, Yaowu, Kryza, Thomas, Harrington, Brittney S, Gunter, Jennifer H, Sullivan, Mitchell A, Cuda, Tahleesa, Rogers, Rebecca, Davies, Claire M, Broomfield, Amy, Gough, Madeline, Wu, Andy C, McGann, Thomas, Weroha, S John, Haluska, Paul, Forbes, Josephine M, Armes, Jane E, Barry, Sinead C, Coward, Jermaine I, Jagasia, Nisha, Chetty, Naven, Snell, Cameron E, Lourie, Rohan, Perrin, Lewis C, Hooper, John D
Published in Cancers (03.04.2020)
Published in Cancers (03.04.2020)
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Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors
Brellier, Florence, Martina, Enrico, Degen, Martin, Heuzé-Vourc'h, Nathalie, Petit, Agnès, Kryza, Thomas, Courty, Yves, Terracciano, Luigi, Ruiz, Christian, Chiquet-Ehrismann, Ruth
Published in BMC clinical pathology (04.09.2012)
Published in BMC clinical pathology (04.09.2012)
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Post-GWAS in prostate cancer: from genetic association to biological contribution
Farashi, Samaneh, Kryza, Thomas, Clements, Judith, Batra, Jyotsna
Published in Nature reviews. Cancer (01.01.2019)
Published in Nature reviews. Cancer (01.01.2019)
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Journal Article
Remodelling of the tumour microenvironment by the kallikrein-related peptidases
Srinivasan, Srilakshmi, Kryza, Thomas, Batra, Jyotsna, Clements, Judith
Published in Nature reviews. Cancer (01.04.2022)
Published in Nature reviews. Cancer (01.04.2022)
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Journal Article
Development of a CUB domain-containing protein 1 (CDCP1)-targeting antibody-drug conjugate for triple-negative and metastatic breast cancer
Gough, Madeline, Kwah, Kayden, He, Yaowu, Snell, Cameron Edward, Hooper, John D., Kryza, Thomas
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
HER2 in situ hybridization testing in breast cancer: Applying algorithm-assisted assessment to reduce interobserver variability in difficult cases
Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D., Lakhani, Sunil R., Snell, Cameron Edward
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Reactive Oxygen Species as Mediators of Disease Progression and Therapeutic Response in Colorectal Cancer
Lyons, Nicholas J, Giri, Rabina, Begun, Jakob, Clark, David, Proud, David, He, Yaowu, Hooper, John D, Kryza, Thomas
Published in Antioxidants & redox signaling (01.07.2023)
Published in Antioxidants & redox signaling (01.07.2023)
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First-in-Human 212Pb-PSMA–Targeted α-Therapy SPECT/CT Imaging in a Patient with Metastatic Castration-Resistant Prostate Cancer
Griffiths, Matthew R, Pattison, David A, Latter, Melissa, Kuan, Kevin, Taylor, Stephen, Tieu, William, Kryza, Thomas, Meyrick, Danielle, Lee, Boon Quan, Hansen, Aaron, Rose, Stephen E, Puttick, Simon G
Published in The Journal of nuclear medicine (1978) (01.04.2024)
Published in The Journal of nuclear medicine (1978) (01.04.2024)
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Journal Article
First-in-Human 212 Pb-PSMA-Targeted α-Therapy SPECT/CT Imaging in a Patient with Metastatic Castration-Resistant Prostate Cancer
Griffiths, Matthew R, Pattison, David A, Latter, Melissa, Kuan, Kevin, Taylor, Stephen, Tieu, William, Kryza, Thomas, Meyrick, Danielle, Lee, Boon Quan, Hansen, Aaron, Rose, Stephen E, Puttick, Simon G
Published in Journal of Nuclear Medicine (01.04.2024)
Published in Journal of Nuclear Medicine (01.04.2024)
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Journal Article
Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome
Silva, Lakmali Munasinghage, Kryza, Thomas, Stoll, Thomas, Hoogland, Christine, Dong, Ying, Stephens, Carson Ryan, Hastie, Marcus Lachlan, Magdolen, Viktor, Kleifeld, Oded, Gorman, Jeffrey John, Clements, Judith Ann
Published in Molecular & cellular proteomics (01.05.2019)
Published in Molecular & cellular proteomics (01.05.2019)
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Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer
Gough, Madeline, Liu, Cheng, Srinivasan, Bhuvana, Wilkinson, Lisa, Dunk, Louisa, Yang, Yuanhao, Schreiber, Veronika, Tuffaha, Haitham, Kryza, Thomas, Hooper, John D, Lakhani, Sunil R, Snell, Cameron E
Published in Histopathology (01.10.2023)
Published in Histopathology (01.10.2023)
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Journal Article
Fibroblast Activation Protein Is Overexpressed on Both Stromal and Epithelial Cells Before Pancreatic Ductal Adenocarcinoma: Implications for Early Diagnosis on 68Ga-FAPI-PET/CT
McGahan, William, Gough, Madeline, Liu, Cheng, Hoyte, Sharon, Gill, Anthony J., Cavallucci, David, Cooper, Caroline, Butler, Nick, Yeung, Shinn, Kryza, Thomas, Gulhane, Brook, Latter, Melissa J., Waddell, Nicola, Samra, Jaswinder S., Simpson, Fiona, Pajic, Marina, Thomas, Paul A., O’Rourke, Thomas, Hooper, John D.
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2024)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2024)
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Journal Article
A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer
Lovell, Scott, Zhang, Leran, Kryza, Thomas, Neodo, Anna, Bock, Nathalie, De Vita, Elena, Williams, Elizabeth D, Engelsberger, Elisabeth, Xu, Congyi, Bakker, Alexander T, Maneiro, Maria, Tanaka, Reiko J, Bevan, Charlotte L, Clements, Judith A, Tate, Edward W
Published in Journal of the American Chemical Society (16.06.2021)
Published in Journal of the American Chemical Society (16.06.2021)
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Journal Article
Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1
Kryza, Thomas, Khan, Tashbib, Lovell, Scott, Harrington, Brittney S., Yin, Julia, Porazinski, Sean, Pajic, Marina, Koistinen, Hannu, Rantala, Juha K., Dreyer, Tobias, Magdolen, Viktor, Reuning, Ute, He, Yaowu, Tate, Edward W., Hooper, John D.
Published in Nature chemical biology (01.07.2021)
Published in Nature chemical biology (01.07.2021)
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