Thyroid and Glucocorticoid Hormones Promote Functional T-Tubule Development in Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes
Parikh, Shan S, Blackwell, Daniel J, Gomez-Hurtado, Nieves, Frisk, Michael, Wang, Lili, Kim, Kyungsoo, Dahl, Christen P, Fiane, Arnt, Tønnessen, Theis, Kryshtal, Dmytro O, Louch, William E, Knollmann, Bjorn C
Published in Circulation research (08.12.2017)
Published in Circulation research (08.12.2017)
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Journal Article
RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT
Kryshtal, Dmytro O, Blackwell, Daniel J, Egly, Christian L, Smith, Abigail N, Batiste, Suzanne M, Johnston, Jeffrey N, Laver, Derek R, Knollmann, Bjorn C
Published in Circulation research (05.02.2021)
Published in Circulation research (05.02.2021)
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Journal Article
Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension
Barbaro, Natalia R., Foss, Jason D., Kryshtal, Dmytro O., Tsyba, Nikita, Kumaresan, Shivani, Xiao, Liang, Mernaugh, Raymond L., Itani, Hana A., Loperena, Roxana, Chen, Wei, Dikalov, Sergey, Titze, Jens M., Knollmann, Bjorn C., Harrison, David G., Kirabo, Annet
Published in Cell reports (Cambridge) (24.10.2017)
Published in Cell reports (Cambridge) (24.10.2017)
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Journal Article
Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories
Hwang, Hyun Seok, Kryshtal, Dmytro O, Feaster, T.K, Sánchez-Freire, Verónica, Zhang, Jianhua, Kamp, Timothy J, Hong, Charles C, Wu, Joseph C, Knollmann, Björn C
Published in Journal of molecular and cellular cardiology (01.08.2015)
Published in Journal of molecular and cellular cardiology (01.08.2015)
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Journal Article
Hypertrophic cardiomyopathy-linked mutation in troponin T causes myofibrillar disarray and pro-arrhythmic action potential changes in human iPSC cardiomyocytes
Wang, Lili, Kim, Kyungsoo, Parikh, Shan, Cadar, Adrian Gabriel, Bersell, Kevin R., He, Huan, Pinto, Jose R., Kryshtal, Dmytro O., Knollmann, Bjorn C.
Published in Journal of molecular and cellular cardiology (01.01.2018)
Published in Journal of molecular and cellular cardiology (01.01.2018)
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Journal Article
Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization
Bersell, Kevin R, Yang, Tao, Mosley, Jonathan D, Glazer, Andrew M, Hale, Andrew T, Kryshtal, Dmytro O, Kim, Kyungsoo, Steimle, Jeffrey D, Brown, Jonathan D, Salem, Joe-Elie, Campbell, Courtney C, Hong, Charles C, Wells, Quinn S, Johnson, Amanda N, Short, Laura, Blair, Marcia A, Behr, Elijah R, Petropoulou, Evmorfia, Jamshidi, Yalda, Benson, Mark D, Keyes, Michelle J, Ngo, Debby, Vasan, Ramachandran S, Yang, Qiong, Gerszten, Robert E, Shaffer, Christian, Parikh, Shan, Sheng, Quanhu, Kannankeril, Prince J, Moskowitz, Ivan P, York, John D, Wang, Thomas J, Knollmann, Bjorn C, Roden, Dan M
Published in Circulation (New York, N.Y.) (07.03.2023)
Published in Circulation (New York, N.Y.) (07.03.2023)
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Journal Article
Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic
Batiste, Suzanne M., Blackwell, Daniel J., Kim, Kyungsoo, Kryshtal, Dmytro O., Gomez-Hurtado, Nieves, Rebbeck, Robyn T., Cornea, Razvan L., Johnston, Jeffrey N., Knollmann, Bjorn C.
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2019)
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Journal Article
Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome–Associated Calmodulin Missense Variant, E141G
Boczek, Nicole J, Gomez-Hurtado, Nieves, Ye, Dan, Calvert, Melissa L, Tester, David J, Kryshtal, Dmytro O, Hwang, Hyun Seok, Johnson, Christopher N, Chazin, Walter J, Loporcaro, Christina G, Shah, Maully, Papez, Andrew L, Lau, Yung R, Kanter, Ronald, Knollmann, Björn C, Ackerman, Michael J
Published in Circulation. Cardiovascular genetics (01.04.2016)
Published in Circulation. Cardiovascular genetics (01.04.2016)
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Journal Article
Impaired Dynamic Sarcoplasmic Reticulum Ca Buffering in Autosomal Dominant CPVT2
Wleklinski, Matthew J, Kryshtal, Dmytro O, Kim, Kyungsoo, Parikh, Shan S, Blackwell, Daniel J, Marty, Isabelle, Iyer, V Ramesh, Knollmann, Bjӧrn C
Published in Circulation research (30.09.2022)
Published in Circulation research (30.09.2022)
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Journal Article
Patient-independent human induced pluripotent stem cell model: A new tool for rapid determination of genetic variant pathogenicity in long QT syndrome
Chavali, Nikhil V., Kryshtal, Dmytro O., Parikh, Shan S., Wang, Lili, Glazer, Andrew M., Blackwell, Daniel J., Kroncke, Brett M., Shoemaker, Moore Benjamin, Knollmann, Bjorn C.
Published in Heart rhythm (01.11.2019)
Published in Heart rhythm (01.11.2019)
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Journal Article
Eicosanoid-Regulated Myeloid ENaC and Isolevuglandin Formation in Human Salt-Sensitive Hypertension
Ertuglu, Lale A, Pitzer Mutchler, Ashley, Jamison, Sydney, Laffer, Cheryl L, Elijovich, Fernando, Saleem, Mohammad, Blackwell, Daniel J, Kryshtal, Dmytro O, Egly, Christian L, Sahinoz, Melis, Sheng, Quanhu, Wanjalla, Celestine N, Pakala, Suman, Yu, Justin, Gutierrez, Orlando M, Kleyman, Thomas R, Knollmann, Björn C, Ikizler, T Alp, Kirabo, Annet
Published in Hypertension (Dallas, Tex. 1979) (01.03.2024)
Published in Hypertension (Dallas, Tex. 1979) (01.03.2024)
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Journal Article
Myofilament Ca Sensitization Increases Cytosolic Ca Binding Affinity, Alters Intracellular Ca Homeostasis, and Causes Pause-Dependent Ca-Triggered Arrhythmia
Schober, Tilmann, Huke, Sabine, Venkataraman, Raghav, Gryshchenko, Oleksiy, Kryshtal, Dmytro, Hwang, Hyun Seok, Baudenbacher, Franz J, Knollmann, Björn C
Published in Circulation research (06.07.2012)
Published in Circulation research (06.07.2012)
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Journal Article
Myofilament Calcium-Buffering Dependent Action Potential Triangulation in Human-Induced Pluripotent Stem Cell Model of Hypertrophic Cardiomyopathy
Wang, Lili, Kryshtal, Dmytro O., Kim, Kyungsoo, Parikh, Shan, Cadar, Adrian Gabriel, Bersell, Kevin Richard, He, Huan, Pinto, Jose R., Knollmann, Bjorn C.
Published in Journal of the American College of Cardiology (14.11.2017)
Published in Journal of the American College of Cardiology (14.11.2017)
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Journal Article
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks
Gomez-Hurtado, Nieves, Boczek, Nicole J, Kryshtal, Dmytro O, Johnson, Christopher N, Sun, Jennifer, Nitu, Florentin R, Cornea, Razvan L, Chazin, Walter J, Calvert, Melissa L, Tester, David J, Ackerman, Michael J, Knollmann, Björn C
Published in Circulation. Arrhythmia and electrophysiology (01.08.2016)
Published in Circulation. Arrhythmia and electrophysiology (01.08.2016)
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Journal Article
Impaired calcium-calmodulin-dependent inactivation of Cav1.2 contributes to loss of sarcoplasmic reticulum calcium release refractoriness in mice lacking calsequestrin 2
Kryshtal, Dmytro O., Gryshchenko, Oleksiy, Gomez-Hurtado, Nieves, Knollmann, Bjorn C.
Published in Journal of molecular and cellular cardiology (01.05.2015)
Published in Journal of molecular and cellular cardiology (01.05.2015)
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Journal Article
Calsequestrin Mutations and Catecholaminergic Polymorphic Ventricular Tachycardia
Faggioni, Michela, Kryshtal, Dmytro O., Knollmann, Björn C.
Published in Pediatric cardiology (01.08.2012)
Published in Pediatric cardiology (01.08.2012)
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Journal Article
Coordinated regulation of murine cardiomyocyte contractility by nanomolar (-)-epigallocatechin-3-gallate, the major green tea catechin
Feng, Wei, Hwang, Hyun Seok, Kryshtal, Dmytro O, Yang, Tao, Padilla, Isela T, Tiwary, Asheesh K, Puschner, Birgit, Pessah, Isaac N, Knollmann, Björn C
Published in Molecular pharmacology (01.11.2012)
Published in Molecular pharmacology (01.11.2012)
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Journal Article
Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes to understand and test cardiac calcium handling: A glass half full
Hwang, Hyun Seok, Kryshtal, Dmytro O, Feaster, Tromondae K, Sánchez-Freire, Verónica, Zhang, Jianhua, Kamp, Timothy J, Hong, Charles C, Wu, Joseph C, Knollmann, Björn C
Published in Journal of molecular and cellular cardiology (01.12.2015)
Published in Journal of molecular and cellular cardiology (01.12.2015)
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Journal Article
Investigation of the regularities of temperature regime of fire in cable tunnels depending on its parameters
Nuianzin, Oleksandr, Kryshtal, Mykola, Nesterenko, Artem, Kryshtal, Dmytro, Samchenko, Taras
Published in MATEC Web of Conferences (01.01.2018)
Published in MATEC Web of Conferences (01.01.2018)
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Journal Article
Conference Proceeding