Two polymorphic cholesterol monohydrate crystal structures form in macrophage culture models of atherosclerosis
Varsano, Neta, Beghi, Fabio, Elad, Nadav, Pereiro, Eva, Dadosh, Tali, Pinkas, Iddo, Perez-Berna, Ana J., Jin, Xueting, Kruth, Howard S., Leiserowitz, Leslie, Addadi, Lia
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2018)
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Development of Correlative Cryo-soft X‑ray Tomography and Stochastic Reconstruction Microscopy. A Study of Cholesterol Crystal Early Formation in Cells
Varsano, Neta, Dadosh, Tali, Kapishnikov, Sergey, Pereiro, Eva, Shimoni, Eyal, Jin, Xueting, Kruth, Howard S, Leiserowitz, Leslie, Addadi, Lia
Published in Journal of the American Chemical Society (16.11.2016)
Published in Journal of the American Chemical Society (16.11.2016)
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Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques
Waldo, Stephen W, Li, Yifu, Buono, Chiara, Zhao, Bin, Billings, Eric M, Chang, Janet, Kruth, Howard S
Published in The American journal of pathology (01.04.2008)
Published in The American journal of pathology (01.04.2008)
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ABCA1 (ATP-Binding Cassette Transporter A1) Mediates ApoA-I (Apolipoprotein A-I) and ApoA-I Mimetic Peptide Mobilization of Extracellular Cholesterol Microdomains Deposited by Macrophages
Jin, Xueting, Sviridov, Denis, Liu, Ying, Vaisman, Boris, Addadi, Lia, Remaley, Alan T, Kruth, Howard S
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2016)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2016)
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Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis
Orekhov, Alexander N, Oishi, Yumiko, Nikiforov, Nikita G, Zhelankin, Andrey V, Dubrovsky, Larisa, Sobenin, Igor A, Kel, Alexander, Stelmashenko, Daria, Makeev, Vsevolod J, Foxx, Kathy, Jin, Xueting, Kruth, Howard S, Bukrinsky, Michael
Published in Current pharmaceutical design (01.01.2018)
Published in Current pharmaceutical design (01.01.2018)
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ABCA1 contributes to macrophage deposition of extracellular cholesterol
Jin, Xueting, Freeman, Sebastian R., Vaisman, Boris, Liu, Ying, Chang, Janet, Varsano, Neta, Addadi, Lia, Remaley, Alan, Kruth, Howard S.
Published in Journal of lipid research (01.09.2015)
Published in Journal of lipid research (01.09.2015)
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Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice[S]
Thacker, Seth G., Rousset, Xavier, Esmail, Safiya, Zarzour, Abdalrahman, Jin, Xueting, Collins, Heidi L., Sampson, Maureen, Stonik, John, Demosky, Stephen, Malide, Daniela A., Freeman, Lita, Vaisman, Boris L., Kruth, Howard S., Adelman, Steven J., Remaley, Alan T.
Published in Journal of lipid research (01.07.2015)
Published in Journal of lipid research (01.07.2015)
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ABCG1-mediated generation of extracellular cholesterol microdomains
Freeman, Sebastian R., Jin, Xueting, Anzinger, Joshua J., Xu, Qing, Purushothaman, Sonya, Fessler, Michael B., Addadi, Lia, Kruth, Howard S.
Published in Journal of lipid research (01.01.2014)
Published in Journal of lipid research (01.01.2014)
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Macropinocytosis Is the Endocytic Pathway That Mediates Macrophage Foam Cell Formation with Native Low Density Lipoprotein
Kruth, Howard S., Jones, Nancy L., Huang, Wei, Zhao, Bin, Ishii, Itsuko, Chang, Janet, Combs, Christian A., Malide, Daniela, Zhang, Wei-Yang
Published in The Journal of biological chemistry (21.01.2005)
Published in The Journal of biological chemistry (21.01.2005)
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Native Low-Density Lipoprotein Uptake by Macrophage Colony-Stimulating Factor-Differentiated Human Macrophages Is Mediated by Macropinocytosis and Micropinocytosis
Anzinger, Joshua J, Chang, Janet, Xu, Qing, Buono, Chiara, Li, Yifu, Leyva, Francisco J, Park, Bum-Chan, Greene, Lois E, Kruth, Howard S
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2010)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2010)
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Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kγ-dependent fluid-phase pinocytosis of native LDL[S]
Anzinger, Joshua J., Chang, Janet, Xu, Qing, Barthwal, Manoj K., Bohnacker, Thomas, Wymann, Matthias P., Kruth, Howard S.
Published in Journal of lipid research (01.01.2012)
Published in Journal of lipid research (01.01.2012)
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UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy
Nickerson, Michael L, Kostiha, Brittany N, Brandt, Wolfgang, Fredericks, William, Xu, Ke-Ping, Yu, Fu-Shin, Gold, Bert, Chodosh, James, Goldberg, Marc, Lu, Da Wen, Yamada, Masakazu, Tervo, Timo M, Grutzmacher, Richard, Croasdale, Chris, Hoeltzenbein, Maria, Sutphin, John, Malkowicz, S Bruce, Wessjohann, Ludger, Kruth, Howard S, Dean, Michael, Weiss, Jayne S
Published in PloS one (21.05.2010)
Published in PloS one (21.05.2010)
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Chronic skin inflammation accelerates macrophage cholesterol crystal formation and atherosclerosis
Baumer, Yvonne, Ng, Qimin, Sanda, Gregory E, Dey, Amit K, Teague, Heather L, Sorokin, Alexander V, Dagur, Pradeep K, Silverman, Joanna I, Harrington, Charlotte L, Rodante, Justin A, Rose, Shawn M, Varghese, Nevin J, Belur, Agastya D, Goyal, Aditya, Gelfand, Joel M, Springer, Danielle A, Bleck, Christopher Ke, Thomas, Crystal L, Yu, Zu-Xi, Winge, Mårten Cg, Kruth, Howard S, Marinkovich, M Peter, Joshi, Aditya A, Playford, Martin P, Mehta, Nehal N
Published in JCI insight (11.01.2018)
Published in JCI insight (11.01.2018)
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Histopathology and regression of retinal hard exudates in diabetic retinopathy after reduction of elevated serum lipid levels
Cusick, Michael, Chew, Emily Y, Chan, Chi-Chao, Kruth, Howard S, Murphy, Robert P, Ferris, Frederick L
Published in Ophthalmology (Rochester, Minn.) (01.11.2003)
Published in Ophthalmology (Rochester, Minn.) (01.11.2003)
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Extracellular cholesterol-rich microdomains generated by human macrophages and their potential function in reverse cholesterol transport
Ong, Daniel S., Anzinger, Joshua J., Leyva, Francisco J., Rubin, Noa, Addadi, Lia, Kruth, Howard S.
Published in Journal of lipid research (01.08.2010)
Published in Journal of lipid research (01.08.2010)
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