Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays
Sztuba-Solinska, Joanna, Shenoy, Shilpa R, Gareiss, Peter, Krumpe, Lauren R. H, Le Grice, Stuart F. J, O’Keefe, Barry R, Schneekloth, John S
Published in Journal of the American Chemical Society (11.06.2014)
Published in Journal of the American Chemical Society (11.06.2014)
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Journal Article
MoMo30 Binds to SARS-CoV-2 Spike Variants and Blocks Infection by SARS-CoV-2 Pseudovirus
DeBarros, Kenya, Khan, Mahfuz, Coleman, Morgan, Bond, Vincent C, Floyd, Virginia, Gbodossou, Erick, Diop, Amad, Krumpe, Lauren R H, O'Keefe, Barry R, Powell, Michael D
Published in Viruses (07.09.2024)
Published in Viruses (07.09.2024)
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Journal Article
The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus
Garrison, Aura R., Giomarelli, Barbara G., Lear-Rooney, Calli M., Saucedo, Carrie J., Yellayi, Srikanth, Krumpe, Lauren R.H., Rose, Maura, Paragas, Jason, Bray, Mike, Olinger, Gene G., McMahon, James B., Huggins, John, O’Keefe, Barry R.
Published in Antiviral research (01.12.2014)
Published in Antiviral research (01.12.2014)
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Journal Article
T7 lytic phage-displayed peptide libraries exhibit less sequence bias than M13 filamentous phage-displayed peptide libraries
Krumpe, Lauren R. H., Atkinson, Andrew J., Smythers, Gary W., Kandel, Andrea, Schumacher, Kathryn M., McMahon, James B., Makowski, Lee, Mori, Toshiyuki
Published in Proteomics (Weinheim) (01.08.2006)
Published in Proteomics (Weinheim) (01.08.2006)
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Journal Article
Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I
Krumpe, Lauren R. H, Wilson, Brice A. P, Marchand, Christophe, Sunassee, Suthananda N, Bermingham, Alun, Wang, Wenjie, Price, Edmund, Guszczynski, Tad, Kelley, James A, Gustafson, Kirk R, Pommier, Yves, Rosengren, K. Johan, Schroeder, Christina I, O’Keefe, Barry R
Published in Journal of the American Chemical Society (16.12.2020)
Published in Journal of the American Chemical Society (16.12.2020)
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Journal Article
Roseabol A, a New Peptaibol from the Fungus Clonostachys rosea
Kim, Chang-Kwon, Krumpe, Lauren R. H., Smith, Emily, Henrich, Curtis J., Brownell, Isaac, Wendt, Karen L., Cichewicz, Robert H., O’Keefe, Barry R., Gustafson, Kirk R.
Published in Molecules (Basel, Switzerland) (11.06.2021)
Published in Molecules (Basel, Switzerland) (11.06.2021)
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Journal Article
Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities
Tran, Trong D, Wilson, Brice A. P, Henrich, Curtis J, Staudt, Louis M, Krumpe, Lauren R. H, Smith, Emily A, King, Jarrod, Wendt, Karen L, Stchigel, Alberto M, Miller, Andrew N, Cichewicz, Robert H, O’Keefe, Barry R, Gustafson, Kirk R
Published in Journal of natural products (Washington, D.C.) (25.01.2019)
Published in Journal of natural products (Washington, D.C.) (25.01.2019)
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Journal Article
Gene-silencing suppressors for high-level production of the HIV-1 entry inhibitor griffithsin in Nicotiana benthamiana
Habibi, Peyman, Soccol, Carlos Ricardo, O’Keefe, Barry R., Krumpe, Lauren R.H., Wilson, Jennifer, de Macedo, Leonardo Lima Pepino, Faheem, Muhammad, Dos Santos, Vanessa Olinto, Prado, Guilherme Souza, Botelho, Marco Antonio, Lacombe, Severine, Grossi-de-Sa, Maria Fatima
Published in Process biochemistry (1991) (01.07.2018)
Published in Process biochemistry (1991) (01.07.2018)
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An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics
Borhani, Shayan G., Levine, Max Z., Krumpe, Lauren H., Wilson, Jennifer, Henrich, Curtis J., O’Keefe, Barry R., Lo, Donald C., Sittampalam, G. Sitta, Godfrey, Alexander G., Lunsford, R. Dwayne, Mangalampalli, Venkata, Tao, Dingyin, LeClair, Christopher A., Thole, Aaron P., Frey, Douglas, Swartz, James, Rao, Govind
Published in New biotechnology (25.09.2023)
Published in New biotechnology (25.09.2023)
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Journal Article
A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity
Woodrum, Brian W, Maxwell, Jason, Allen, Denysia M, Wilson, Jennifer, Krumpe, Lauren R H, Bobkov, Andrey A, Hill, R Blake, Kibler, Karen V, O'Keefe, Barry R, Ghirlanda, Giovanna
Published in Viruses (06.06.2016)
Published in Viruses (06.06.2016)
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Journal Article
The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation
Matarlo, Joe S, Krumpe, Lauren R H, Heinz, William F, Oh, Daniel, Shenoy, Shilpa R, Thomas, Cheryl L, Goncharova, Ekaterina I, Lockett, Stephen J, O'Keefe, Barry R
Published in Cell chemical biology (15.08.2019)
Published in Cell chemical biology (15.08.2019)
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Journal Article
Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge
Lo, Michael K, Spengler, Jessica R, Krumpe, Lauren R H, Welch, Stephen R, Chattopadhyay, Anasuya, Harmon, Jessica R, Coleman-McCray, JoAnn D, Scholte, Florine E M, Hotard, Anne L, Fuqua, Joshua L, Rose, John K, Nichol, Stuart T, Palmer, Kenneth E, O’Keefe, Barry R, Spiropoulou, Christina F
Published in The Journal of Infectious Diseases (11.05.2020)
Published in The Journal of Infectious Diseases (11.05.2020)
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Journal Article
Web Resource
Picking the tyrosine-lock: chemical synthesis of the tyrosyl-DNA phosphodiesterase I inhibitor recifin A and analogues
Smallwood, Taylor B, Krumpe, Lauren R H, Payne, Colton D, Klein, Victoria G, O'Keefe, Barry R, Clark, Richard J, Schroeder, Christina I, Rosengren, K Johan
Published in Chemical science (Cambridge) (22.08.2024)
Published in Chemical science (Cambridge) (22.08.2024)
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Journal Article
Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2
Muñoz-Basagoiti, Jordana, Monteiro, Fábio Luís Lima, Krumpe, Lauren R H, Armario-Najera, Victoria, Shenoy, Shilpa R, Perez-Zsolt, Daniel, Westgarth, Harrison James, Villorbina, Gemma, Bomfim, Larissa Maciel, Raïch-Regué, Dàlia, Nogueras, Lara, Henrich, Curtis J, Gallemí, Marçal, Moreira, Filipe Romero Rebello, Torres, Pascual, Wilson, Jennifer, D'arc, Mirela, Marfil, Silvia, Herlinger, Alice Laschuk, Pradenas, Edwards, Higa, Luiza Mendonça, Portero-Otin, Manuel, Trinité, Benjamin, Twyman, Richard M, Capell, Teresa, Tanuri, Amilcar, Blanco, Julià, Izquierdo-Useros, Nuria, Rech, Elibio L, Christou, Paul, O'Keefe, Barry R
Published in Proceedings of the National Academy of Sciences - PNAS (07.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (07.03.2023)
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Journal Article
Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus
Moulaei, Tinoush, Alexandre, Kabamba B, Shenoy, Shilpa R, Meyerson, Joel R, Krumpe, Lauren Rh, Constantine, Brian, Wilson, Jennifer, Buckheit, Jr, Robert W, McMahon, James B, Subramaniam, Sriram, Wlodawer, Alexander, O'Keefe, Barry R
Published in Retrovirology (23.01.2015)
Published in Retrovirology (23.01.2015)
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Journal Article
Trinucleotide cassettes increase diversity of T7 phage-displayed peptide library
Krumpe, Lauren R H, Schumacher, Kathryn M, McMahon, James B, Makowski, Lee, Mori, Toshiyuki
Published in BMC biotechnology (05.10.2007)
Published in BMC biotechnology (05.10.2007)
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Journal Article
Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)
Bermingham, Alun, Price, Edmund, Marchand, Christophe, Chergui, Adel, Naumova, Alena, Whitson, Emily L., Krumpe, Lauren R. H., Goncharova, Ekaterina I., Evans, Jason R., McKee, Tawnya C., Henrich, Curtis J., Pommier, Yves, O’Keefe, Barry R.
Published in SLAS discovery (01.10.2017)
Published in SLAS discovery (01.10.2017)
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Journal Article
An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics
Borhani, Shayan G, Levine, Max Z, Krumpe, Lauren H, Wilson, Jennifer, Henrich, Curtis J, Oâ Keefe, Barry R, Lo, Donald, Sittampalam, G Sitta, Godfrey, Alexander G, Lunsford, R Dwayne, Mangalampalli, Venkata, Tao, Dingyin, LeClair, Christopher A, Thole, Aaron, Frey, Douglas, Swartz, James, Rao, Govind
Published in bioRxiv : the preprint server for biology (20.12.2022)
Published in bioRxiv : the preprint server for biology (20.12.2022)
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Journal Article
The Use of Phage-Displayed Peptide Libraries to Develop Tumor-Targeting Drugs
Krumpe, Lauren R H, Mori, Toshiyuki
Published in International journal of peptide research and therapeutics (01.03.2006)
Published in International journal of peptide research and therapeutics (01.03.2006)
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Journal Article
T7 lytic phage-displayed peptide libraries: construction and diversity characterization
Krumpe, Lauren R H, Mori, Toshiyuki
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
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