Tunable and reversible drug control of protein production via a self-excising degron
Chung, Hokyung K, Jacobs, Conor L, Huo, Yunwen, Yang, Jin, Krumm, Stefanie A, Plemper, Richard K, Tsien, Roger Y, Lin, Michael Z
Published in Nature chemical biology (01.09.2015)
Published in Nature chemical biology (01.09.2015)
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The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection
Arieta, Christina M., Xie, Yushu Joy, Rothenberg, Daniel A., Diao, Huitian, Harjanto, Dewi, Meda, Shirisha, Marquart, Krisann, Koenitzer, Byron, Sciuto, Tracey E., Lobo, Alexander, Zuiani, Adam, Krumm, Stefanie A., Cadima Couto, Carla Iris, Hein, Stephanie, Heinen, André P., Ziegenhals, Thomas, Liu-Lupo, Yunpeng, Vogel, Annette B., Srouji, John R., Fesser, Stephanie, Thanki, Kaushik, Walzer, Kerstin, Addona, Theresa A., Türeci, Özlem, Şahin, Uğur, Gaynor, Richard B., Poran, Asaf
Published in Cell (25.05.2023)
Published in Cell (25.05.2023)
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Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies
Pritchard, Laura K., Spencer, Daniel I.R., Royle, Louise, Bonomelli, Camille, Seabright, Gemma E., Behrens, Anna-Janina, Kulp, Daniel W., Menis, Sergey, Krumm, Stefanie A., Dunlop, D. Cameron, Crispin, Daniel J., Bowden, Thomas A., Scanlan, Christopher N., Ward, Andrew B., Schief, William R., Doores, Katie J., Crispin, Max
Published in Nature communications (24.06.2015)
Published in Nature communications (24.06.2015)
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Journal Article
EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression
Currier, Michael G, Lee, Sujin, Stobart, Christopher C, Hotard, Anne L, Villenave, Remi, Meng, Jia, Pretto, Carla D, Shields, Michael D, Nguyen, Minh Trang, Todd, Sean O, Chi, Michael H, Hammonds, Jason, Krumm, Stefanie A, Spearman, Paul, Plemper, Richard K, Sakamoto, Kaori, Peebles, Jr, R Stokes, Power, Ultan F, Moore, Martin L
Published in PLoS pathogens (01.05.2016)
Published in PLoS pathogens (01.05.2016)
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Journal Article
Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope
Doores, Katie J, Kong, Leopold, Krumm, Stefanie A, Le, Khoa M, Sok, Devin, Laserson, Uri, Garces, Fernando, Poignard, Pascal, Wilson, Ian A, Burton, Dennis R
Published in Journal of virology (15.01.2015)
Published in Journal of virology (15.01.2015)
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Journal Article
HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual
Coss, Karen P, Vasiljevic, Snezana, Pritchard, Laura K, Krumm, Stefanie A, Glaze, Molly, Madzorera, Sharon, Moore, Penny L, Crispin, Max, Doores, Katie J
Published in Journal of virology (15.12.2016)
Published in Journal of virology (15.12.2016)
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Journal Article
A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus
Allen, Elizabeth R., Krumm, Stefanie A., Raghwani, Jayna, Halldorsson, Steinar, Elliott, Angela, Graham, Victoria A., Koudriakova, Elina, Harlos, Karl, Wright, Daniel, Warimwe, George M., Brennan, Benjamin, Huiskonen, Juha T., Dowall, Stuart D., Elliott, Richard M., Pybus, Oliver G., Burton, Dennis R., Hewson, Roger, Doores, Katie J., Bowden, Thomas A.
Published in Cell reports (Cambridge) (26.12.2018)
Published in Cell reports (Cambridge) (26.12.2018)
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Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies
Ng, Weng M, Sahin, Mehmet, Krumm, Stefanie A, Seow, Jeffrey, Zeltina, Antra, Harlos, Karl, Paesen, Guido C, Pinschewer, Daniel D, Doores, Katie J, Bowden, Thomas A
Published in mBio (26.04.2022)
Published in mBio (26.04.2022)
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Journal Article
Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen
Rissanen, Ilona, Krumm, Stefanie A, Stass, Robert, Whitaker, Annalis, Voss, James E, Bruce, Emily A, Rothenberger, Sylvia, Kunz, Stefan, Burton, Dennis R, Huiskonen, Juha T, Botten, Jason W, Bowden, Thomas A, Doores, Katie J
Published in mBio (31.08.2021)
Published in mBio (31.08.2021)
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Journal Article
Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein
Rissanen, Ilona, Stass, Robert, Krumm, Stefanie A, Seow, Jeffrey, Hulswit, Ruben Jg, Paesen, Guido C, Hepojoki, Jussi, Vapalahti, Olli, Lundkvist, Åke, Reynard, Olivier, Volchkov, Viktor, Doores, Katie J, Huiskonen, Juha T, Bowden, Thomas A
Published in eLife (22.12.2020)
Published in eLife (22.12.2020)
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Glycan Microheterogeneity at the PGT135 Antibody Recognition Site on HIV-1 gp120 Reveals a Molecular Mechanism for Neutralization Resistance
Pritchard, Laura K, Spencer, Daniel I R, Royle, Louise, Vasiljevic, Snezana, Krumm, Stefanie A, Doores, Katie J, Crispin, Max
Published in Journal of virology (01.07.2015)
Published in Journal of virology (01.07.2015)
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Journal Article
Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization
Zeltina, Antra, Krumm, Stefanie A., Sahin, Mehmet, Struwe, Weston B., Harlos, Karl, Nunberg, Jack H., Crispin, Max, Pinschewer, Daniel D., Doores, Katie J., Bowden, Thomas A.
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
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Journal Article
Potent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerases
Krumm, Stefanie A, Ndungu, J Maina, Yoon, Jeong-Joong, Dochow, Melanie, Sun, Aiming, Natchus, Michael, Snyder, James P, Plemper, Richard K
Published in PloS one (16.05.2011)
Published in PloS one (16.05.2011)
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Journal Article
Targeting Glycans on Human Pathogens for Vaccine Design
Krumm, Stefanie A, Doores, Katie J
Published in Current topics in microbiology and immunology (01.01.2020)
Published in Current topics in microbiology and immunology (01.01.2020)
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Journal Article
The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans
Hopper, Jonathan T.S., Ambrose, Stephen, Grant, Oliver C., Krumm, Stefanie A., Allison, Timothy M., Degiacomi, Matteo T., Tully, Mark D., Pritchard, Laura K., Ozorowski, Gabriel, Ward, Andrew B., Crispin, Max, Doores, Katie J., Woods, Robert J., Benesch, Justin L.P., Robinson, Carol V., Struwe, Weston B.
Published in Structure (London) (02.05.2017)
Published in Structure (London) (02.05.2017)
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Journal Article
Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies
Krumm, Stefanie A, Mohammed, Hajer, Le, Khoa M, Crispin, Max, Wrin, Terri, Poignard, Pascal, Burton, Dennis R, Doores, Katie J
Published in Retrovirology (02.02.2016)
Published in Retrovirology (02.02.2016)
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Journal Article
Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans
Huettner, Isabella, Krumm, Stefanie A., Serna, Sonia, Brzezicka, Katarzyna, Monaco, Serena, Walpole, Samuel, van Diepen, Angela, Allan, Fiona, Hicks, Thomas, Kimuda, Simon, Emery, Aidan M., Allen, Susan, Kilembe, William, Lakhi, Shabir, Inambao, Mubiana, Karita, Etienne, Kamali, Anatoli, Sanders, Eduard J., Anzala, Omu, Edward, Vinodh, Bekker, Linda-Gail, Tang, Jianming, Gilmour, Jill, Hunter, Eric, Price, Matt, Landais, Elise, Hokke, Cornelis H., Angulo, Jesus, Reichardt, Niels, Doores, Katie J.
Published in Cell reports (Cambridge) (29.03.2022)
Published in Cell reports (Cambridge) (29.03.2022)
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Probing the Spatial Organization of Measles Virus Fusion Complexes
PAAL, Tanja, BRINDLEY, Melinda A, CLAIR, Courtney St, PRUSSIA, Andrew, GAUS, Dominika, KRUMM, Stefanie A, SNYDER, James P, PLEMPER, Richard K
Published in Journal of Virology (15.10.2009)
Published in Journal of Virology (15.10.2009)
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An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model
Krumm, Stefanie A, Yan, Dan, Hovingh, Elise S, Evers, Taylor J, Enkirch, Theresa, Reddy, G Prabhakar, Sun, Aiming, Saindane, Manohar T, Arrendale, Richard F, Painter, George, Liotta, Dennis C, Natchus, Michael G, von Messling, Veronika, Plemper, Richard K
Published in Science translational medicine (16.04.2014)
Published in Science translational medicine (16.04.2014)
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