Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease
Bartus, Raymond T, Baumann, Tiffany L, Brown, Lamar, Kruegel, Brian R, Ostrove, Jeffrey M, Herzog, Christopher D
Published in Neurobiology of aging (2013)
Published in Neurobiology of aging (2013)
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Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120)
Herzog, Christopher D, Brown, Lamar, Kruegel, Brian R, Wilson, Alistair, Tansey, Malú G, Gage, Fred H, Johnson, Eugene M, Bartus, Raymond T
Published in Neurobiology of disease (01.10.2013)
Published in Neurobiology of disease (01.10.2013)
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Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: Support for nigral targeting in Parkinson's disease
Bartus, Raymond T, Brown, Lamar, Wilson, Alistair, Kruegel, Brian, Siffert, Joao, Johnson, Eugene M, Kordower, Jeffrey H, Herzog, Christopher D
Published in Neurobiology of disease (01.10.2011)
Published in Neurobiology of disease (01.10.2011)
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Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease
Herzog, Christopher D, Brown, Lamar, Gammon, Dawn, Kruegel, Brian, Lin, Richard, Wilson, Alistair, Bolton, Ariadne, Printz, Marie, Gasmi, Mehdi, Bishop, Kathie M, Kordower, Jeffrey H, Bartus, Raymond T
Published in Neurosurgery (01.04.2009)
Published in Neurosurgery (01.04.2009)
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Journal Article
Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating aclinical proof-of-concepta for AAV-neurturin (CERE-120) in Parkinson's disease
Bartus, Raymond T, Baumann, Tiffany L, Brown, Lamar, Kruegel, Brian R, Ostrove, Jeffrey M, Herzog, Christopher D
Published in Neurobiology of aging (01.01.2013)
Published in Neurobiology of aging (01.01.2013)
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EXPRESSION, BIOACTIVITY, AND SAFETY 1 YEAR AFTER ADENO-ASSOCIATED VIRAL VECTOR TYPE 2-MEDIATED DELIVERY OF NEURTURIN TO THE MONKEY NIGROSTRIATAL SYSTEM SUPPORT CERE-120 FOR PARKINSON'S DISEASE. Commentaries
HERZOG, Christopher D, BROWN, Lamar, KORDOWER, Jeffrey H, BARTUS, Raymond T, FRANZ, Colin K, STARR, Philip A, GAMMON, Dawn, KRUEGEL, Brian, LIN, Richard, WILSON, Alistair, BOLTON, Ariadne, PRINTZ, Marie, GASMI, Mehdi, BISHOP, Kathie M
Published in Neurosurgery (2009)
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Published in Neurosurgery (2009)
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513. A Simple Method To Ensure Titer Conservation of AAV2 Vector Preparations Delivered with Stainless Steel Needles
Ketchum, Elias T., Kwok, Kevin, Ramirez, Anthony, Hao, Junshan, Kruegel, Brian, Vacante, Dominick, Bartus, Raymond, Gasmi, Mehdi
Published in Molecular therapy (01.05.2006)
Published in Molecular therapy (01.05.2006)
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527. CERE-110, an AAV2-Based Vector To Deliver NGF, Provides Trophic Activity to Basal Forebrain Cholinergic Neurons in Rats and Cynomolgous Monkeys
Bishop, Kathie M, Hofer, Katrin, Rius, Denise, Mehta, Arpesh, Lawandry, Shokry, Brown, Lamar, Kruegel, Brian, Gasmi, Mehdi, Tuszynski, Mark, Bartus, Raymond T
Published in Molecular therapy (01.05.2004)
Published in Molecular therapy (01.05.2004)
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