Trastuzumab emtansine versus capecitabine plus lapatinib in patients with previously treated HER2-positive advanced breast cancer (EMILIA): a descriptive analysis of final overall survival results from a randomised, open-label, phase 3 trial
Diéras, Véronique, Dr, Miles, David, Prof, Verma, Sunil, MD, Pegram, Mark, Prof, Welslau, Manfred, MD, Baselga, José, MD, Krop, Ian E, MD, Blackwell, Kim, Prof, Hoersch, Silke, MSc, Xu, Jin, PhD, Green, Marjorie, MD, Gianni, Luca, MD
Published in The lancet oncology (01.06.2017)
Published in The lancet oncology (01.06.2017)
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Trastuzumab emtansine versus treatment of physician's choice in patients with previously treated HER2-positive metastatic breast cancer (TH3RESA): final overall survival results from a randomised open-label phase 3 trial
Krop, Ian E, Dr, Kim, Sung-Bae, Prof, Martin, Antonio Gonzalez, MD, LoRusso, Patricia M, Prof, Ferrero, Jean-Marc, MD, Badovinac-Crnjevic, Tanja, MD, Hoersch, Silke, MSc, Smitt, Melanie, MD, Wildiers, Hans, Prof
Published in The lancet oncology (01.06.2017)
Published in The lancet oncology (01.06.2017)
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TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes
Tung, Nadine M, Robson, Mark E, Ventz, Steffen, Santa-Maria, Cesar A, Nanda, Rita, Marcom, Paul K, Shah, Payal D, Ballinger, Tarah J, Yang, Eddy S, Vinayak, Shaveta, Melisko, Michelle, Brufsky, Adam, DeMeo, Michelle, Jenkins, Colby, Domchek, Susan, D'Andrea, Alan, Lin, Nancy U, Hughes, Melissa E, Carey, Lisa A, Wagle, Nick, Wulf, Gerburg M, Krop, Ian E, Wolff, Antonio C, Winer, Eric P, Garber, Judy E
Published in Journal of clinical oncology (20.12.2020)
Published in Journal of clinical oncology (20.12.2020)
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Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial
Krop, Ian E, Dr, Kim, Sung-Bae, Prof, González-Martín, Antonio, MD, LoRusso, Patricia M, Prof, Ferrero, Jean-Marc, Prof, Smitt, Melanie, MD, Yu, Ron, PhD, Leung, Abraham C F, MD, Wildiers, Hans, Prof
Published in The lancet oncology (01.06.2014)
Published in The lancet oncology (01.06.2014)
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Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer
Barroso-Sousa, Romualdo, Keenan, Tanya E, Pernas, Sonia, Exman, Pedro, Jain, Esha, Garrido-Castro, Ana C, Hughes, Melissa, Bychkovsky, Brittany, Umeton, Renato, Files, Janet L, Lindeman, Neal I, MacConaill, Laura E, Hodi, F Stephen, Krop, Ian E, Dillon, Deborah, Winer, Eric P, Wagle, Nikhil, Lin, Nancy U, Mittendorf, Elizabeth A, Van Allen, Eliezer M, Tolaney, Sara M
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
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A Phase II Study of Trastuzumab Emtansine in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer Who Were Previously Treated With Trastuzumab, Lapatinib, an Anthracycline, a Taxane, and Capecitabine
KROP, Ian E, LORUSSO, Patricia, AMLER, Lukas, WINER, Eric P, RUGO, Hope S, MILLER, Kathy D, MODI, Shanu, YARDLEY, Denise, RODRIGUEZ, Gladys, GUARDINO, Ellie, LU, Michael, MAOXIA ZHENG, GIRISH, Sandhya
Published in Journal of clinical oncology (10.09.2012)
Published in Journal of clinical oncology (10.09.2012)
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Management of Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: ASCO Guideline Update
Ramakrishna, Naren, Anders, Carey K, Lin, Nancy U, Morikawa, Aki, Temin, Sarah, Chandarlapaty, Sarat, Crews, Jennie R, Davidson, Nancy E, Franzoi, Maria Alice B, Kirshner, Jeffrey J, Krop, Ian E, Patt, Debra A, Perlmutter, Jane, Giordano, Sharon H
Published in Journal of clinical oncology (10.08.2022)
Published in Journal of clinical oncology (10.08.2022)
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Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
Incio, Joao, Ligibel, Jennifer A, McManus, Daniel T, Suboj, Priya, Jung, Keehoon, Kawaguchi, Kosuke, Pinter, Matthias, Babykutty, Suboj, Chin, Shan M, Vardam, Trupti D, Huang, Yuhui, Rahbari, Nuh N, Roberge, Sylvie, Wang, Dannie, Gomes-Santos, Igor L, Puchner, Stefan B, Schlett, Christopher L, Hoffmman, Udo, Ancukiewicz, Marek, Tolaney, Sara M, Krop, Ian E, Duda, Dan G, Boucher, Yves, Fukumura, Dai, Jain, Rakesh K
Published in Science translational medicine (14.03.2018)
Published in Science translational medicine (14.03.2018)
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Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients
Tolaney, Sara M., Boucher, Yves, Duda, Dan G., Martin, John D., Seano, Giorgio, Ancukiewicz, Marek, Barry, William T., Goel, Shom, Lahdenrata, Johanna, Isakoff, Steven J., Yeh, Eren D., Jain, Saloni R., Golshan, Mehra, Brock, Jane, Snuderl, Matija, Winer, Eric P., Krop, Ian E., Jain, Rakesh K.
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2015)
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Phase II Study of the Antibody Drug Conjugate Trastuzumab-DM1 for the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2) –Positive Breast Cancer After Prior HER2-Directed Therapy
BURRIS, Howard A, RUGO, Hope S, AMLER, Lukas, MAOXIA ZHENG, CHU, Yu-Waye, KLENCKE, Barbara, O'SHAUGHNESSY, Joyce A, VUKELJA, Svetislava J, VOGEL, Charles L, BORSON, Rachel A, LIMENTANI, Steven, TAN-CHIU, Elizabeth, KROP, Ian E, MICHAELSON, Richard A, GIRISH, Sandhya
Published in Journal of clinical oncology (01.02.2011)
Published in Journal of clinical oncology (01.02.2011)
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Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial
Krop, Ian E, Dr, Mayer, Ingrid A, MD, Ganju, Vinod, FRACP, Dickler, Maura, MD, Johnston, Stephen, MD, Morales, Serafin, MD, Yardley, Denise A, MD, Melichar, Bohuslav, Prof, Forero-Torres, Andres, MD, Lee, Soo Chin, MRCP, de Boer, Richard, FRACP, Petrakova, Katarina, PhD, Vallentin, Susanne, MD, Perez, Edith A, MD, Piccart, Martine, Prof, Ellis, Matthew, Prof, Winer, Eric, Prof, Gendreau, Steven, PhD, Derynck, Mika, MD, Lackner, Mark, PhD, Levy, Gallia, MD, Qiu, Jiaheng, PhD, He, Jing, MD, Schmid, Peter, Prof
Published in The lancet oncology (01.06.2016)
Published in The lancet oncology (01.06.2016)
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Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer
Garrido-Castro, Ana C, Saura, Cristina, Barroso-Sousa, Romualdo, Guo, Hao, Ciruelos, Eva, Bermejo, Begoña, Gavilá, Joaquin, Serra, Violeta, Prat, Aleix, Paré, Laia, Céliz, Pamela, Villagrasa, Patricia, Li, Yisheng, Savoie, Jennifer, Xu, Zhan, Arteaga, Carlos L, Krop, Ian E, Solit, David B, Mills, Gordon B, Cantley, Lewis C, Winer, Eric P, Lin, Nancy U, Rodon, Jordi
Published in Breast cancer research : BCR (02.11.2020)
Published in Breast cancer research : BCR (02.11.2020)
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Phase I Study of Trastuzumab-DM1, an HER2 Antibody-Drug Conjugate, Given Every 3 Weeks to Patients With HER2-Positive Metastatic Breast Cancer
KROP, Ian E, BEERAM, Muralidhar, JACOBSON, Fred, LUTZKER, Stuart G, BURRIS, Howard A, MODI, Shanu, JONES, Suzanne F, HOLDEN, Scott N, WEI YU, GIRISH, Sandhya, TIBBITTS, Jay, YI, Joo-Hee, SLIWKOWSKI, Mark X
Published in Journal of clinical oncology (01.06.2010)
Published in Journal of clinical oncology (01.06.2010)
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Role of Patient and Disease Factors in Adjuvant Systemic Therapy Decision Making for Early-Stage, Operable Breast Cancer: American Society of Clinical Oncology Endorsement of Cancer Care Ontario Guideline Recommendations
Henry, N Lynn, Somerfield, Mark R, Abramson, Vandana G, Allison, Kimberly H, Anders, Carey K, Chingos, Diana T, Hurria, Arti, Openshaw, Thomas H, Krop, Ian E
Published in Journal of clinical oncology (01.07.2016)
Published in Journal of clinical oncology (01.07.2016)
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PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity
Incio, Joao, Tam, Josh, Rahbari, Nuh N, Suboj, Priya, McManus, Dan T, Chin, Shan M, Vardam, Trupti D, Batista, Ana, Babykutty, Suboj, Jung, Keehoon, Khachatryan, Anna, Hato, Tai, Ligibel, Jennifer A, Krop, Ian E, Puchner, Stefan B, Schlett, Christopher L, Hoffmman, Udo, Ancukiewicz, Marek, Shibuya, Masabumi, Carmeliet, Peter, Soares, Raquel, Duda, Dan G, Jain, Rakesh K, Fukumura, Dai
Published in Clinical cancer research (15.06.2016)
Published in Clinical cancer research (15.06.2016)
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Immune Signatures Following Single Dose Trastuzumab Predict Pathologic Response to PreoperativeTrastuzumab and Chemotherapy in HER2-Positive Early Breast Cancer
Varadan, Vinay, Gilmore, Hannah, Miskimen, Kristy L S, Tuck, David, Parsai, Shikha, Awadallah, Amad, Krop, Ian E, Winer, Eric P, Bossuyt, Veerle, Somlo, George, Abu-Khalaf, Maysa M, Fenton, Mary Anne, Sikov, William, Harris, Lyndsay N
Published in Clinical cancer research (01.07.2016)
Published in Clinical cancer research (01.07.2016)
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Feasibility and cardiac safety of trastuzumab emtansine after anthracycline-based chemotherapy as (neo)adjuvant therapy for human epidermal growth factor receptor 2-positive early-stage breast cancer
Krop, Ian E, Suter, Thomas M, Dang, Chau T, Dirix, Luc, Romieu, Gilles, Zamagni, Claudio, Citron, Marc L, Campone, Mario, Xu, Na, Smitt, Melanie, Gianni, Luca
Published in Journal of clinical oncology (01.04.2015)
Published in Journal of clinical oncology (01.04.2015)
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Clinical pharmacology of trastuzumab emtansine (T-DM1): an antibody–drug conjugate in development for the treatment of HER2-positive cancer
Girish, Sandhya, Gupta, Manish, Wang, Bei, Lu, Dan, Krop, Ian E., Vogel, Charles L., Burris III, Howard A., LoRusso, Patricia M., Yi, Joo-Hee, Saad, Ola, Tong, Barbara, Chu, Yu-Waye, Holden, Scott, Joshi, Amita
Published in Cancer chemotherapy and pharmacology (01.05.2012)
Published in Cancer chemotherapy and pharmacology (01.05.2012)
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