Design, Synthesis, and Structure–Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5‑Lipoxygenase
Hiesinger, Kerstin, Kramer, Jan S, Beyer, Sandra, Eckes, Timon, Brunst, Steffen, Flauaus, Cathrin, Wittmann, Sandra K, Weizel, Lilia, Kaiser, Astrid, Kretschmer, Simon B. M, George, Sven, Angioni, Carlo, Heering, Jan, Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Schmidtko, Achim, Pogoryelov, Denys, Pfeilschifter, Josef, Hofmann, Bettina, Steinhilber, Dieter, Schwalm, Stephanie, Proschak, Ewgenij
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Journal Article
Development of novel aminothiazole-comprising 5-LO inhibitors
M Kretschmer, Simon B, Woltersdorf, Stefano, Rödl, Carmen B, Vogt, Dominik, Häfner, Ann-Kathrin, Steinhilber, Dieter, Stark, Holger, Hofmann, Bettina
Published in Future medicinal chemistry (01.01.2016)
Published in Future medicinal chemistry (01.01.2016)
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Journal Article
Intraoperative blood loss in bimaxillary orthognathic surgery with multisegmental Le Fort I osteotomies and additional procedures
Kretschmer, W.B, Baciut, G, Bacuit, Mihaela, Zoder, W, Wangerin, K
Published in British journal of oral & maxillofacial surgery (01.06.2010)
Published in British journal of oral & maxillofacial surgery (01.06.2010)
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Journal Article
Accuracy of maxillary positioning in bimaxillary surgery
Kretschmer, W.B, Zoder, W, Baciut, G, Bacuit, Mihaela, Wangerin, K
Published in British journal of oral & maxillofacial surgery (01.09.2009)
Published in British journal of oral & maxillofacial surgery (01.09.2009)
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Journal Article
The influence of expansion on intraoperative bone blood flow in multisegmental maxillary osteotomies: an experimental study
Kretschmer, W.B, Baciut, G, Dinu, C, Baciut, M, Barbur, I, Muste, A, Dietz, K
Published in International journal of oral and maxillofacial surgery (01.03.2010)
Published in International journal of oral and maxillofacial surgery (01.03.2010)
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Journal Article
Riluzole, a glutamate release inhibitor, and motor behavior
Kretschmer, B D, Kratzer, U, Schmidt, W J
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.1998)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.08.1998)
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Journal Article
Modulation of ventral pallidal dopamine and glutamate release by the intravenous anesthetic propofol studied by in vivo microdialysis
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Journal Article
Conference Proceeding
Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism
Rödl, Carmen B., Vogt, Dominik, Kretschmer, Simon B.M., Ihlefeld, Katja, Barzen, Sebastian, Brüggerhoff, Astrid, Achenbach, Janosch, Proschak, Ewgenij, Steinhilber, Dieter, Stark, Holger, Hofmann, Bettina
Published in European journal of medicinal chemistry (12.09.2014)
Published in European journal of medicinal chemistry (12.09.2014)
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Journal Article
Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418
Maucher, Isabelle V., Rühl, Michael, Kretschmer, Simon B.M., Hofmann, Bettina, Kühn, Benjamin, Fettel, Jasmin, Vogel, Anja, Flügel, Karsten T., Manolikakes, Georg, Hellmuth, Nadine, Häfner, Ann-Kathrin, Golghalyani, Vahid, Ball, Ann-Katrin, Piesche, Matthias, Matrone, Carmela, Geisslinger, Gerd, Parnham, Michael J., Karas, Michael, Steinhilber, Dieter, Roos, Jessica, Maier, Thorsten J.
Published in Biochemical pharmacology (01.02.2017)
Published in Biochemical pharmacology (01.02.2017)
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Journal Article
Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles
Kretschmer, Simon B.M., Woltersdorf, Stefano, Vogt, Dominik, Lillich, Felix F., Rühl, Michael, Karas, Michael, Maucher, Isabelle V., Roos, Jessica, Häfner, Ann-Kathrin, Kaiser, Astrid, Wurglics, Mario, Schubert-Zsilavecz, Manfred, Angioni, Carlo, Geisslinger, Gerd, Stark, Holger, Steinhilber, Dieter, Hofmann, Bettina
Published in Biochemical pharmacology (01.01.2017)
Published in Biochemical pharmacology (01.01.2017)
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Journal Article