Combination protein biomarkers predict multiple sclerosis diagnosis and outcomes
Kodosaki, Eleftheria, Watkins, W John, Loveless, Sam, Kreft, Karim L, Richards, Aidan, Anderson, Valerie, Hurler, Lisa, Robertson, Neil P, Zelek, Wioleta M, Tallantyre, Emma C
Published in Journal of neuroinflammation (17.02.2024)
Published in Journal of neuroinflammation (17.02.2024)
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Journal Article
Priming of microglia in a DNA-repair deficient model of accelerated aging
Raj, Divya D.A, Jaarsma, Dick, Holtman, Inge R, Olah, Marta, Ferreira, Filipa M, Schaafsma, Wandert, Brouwer, Nieske, Meijer, Michel M, de Waard, Monique C, van der Pluijm, Ingrid, Brandt, Renata, Kreft, Karim L, Laman, Jon D, de Haan, Gerald, Biber, Knut P.H, Hoeijmakers, Jan H.J, Eggen, Bart J.L, Boddeke, Hendrikus W.G.M
Published in Neurobiology of aging (01.09.2014)
Published in Neurobiology of aging (01.09.2014)
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Journal Article
Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis
van Luijn, Marvin M, Kreft, Karim L, Jongsma, Marlieke L, Mes, Steven W, Wierenga-Wolf, Annet F, van Meurs, Marjan, Melief, Marie-José, der Kant, Rik van, Janssen, Lennert, Janssen, Hans, Tan, Rusung, Priatel, John J, Neefjes, Jacques, Laman, Jon D, Hintzen, Rogier Q
Published in Brain (London, England : 1878) (01.06.2015)
Published in Brain (London, England : 1878) (01.06.2015)
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Journal Article
Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation
Huizinga, Ruth, Kreft, Karim L, Onderwater, Sabina, Boonstra, Joke G, Brands, Ruud, Hintzen, Rogier Q, Laman, Jon D
Published in Journal of neuroinflammation (11.12.2012)
Published in Journal of neuroinflammation (11.12.2012)
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Journal Article
Prodromal multiple sclerosis: considerations and future utility
Harding, Katharine E., Kreft, Karim L., Ben-Shlomo, Yoav, Robertson, Neil P.
Published in Journal of neurology (01.04.2024)
Published in Journal of neurology (01.04.2024)
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Journal Article
Relevance of Multiple Sclerosis Severity Genotype in Predicting Disease Course: A Real‐World Cohort
Kreft, Karim L., Uzochukwu, Emeka, Loveless, Sam, Willis, Mark, Wynford‐Thomas, Ray, Harding, Katharine E., Holmans, Peter, Lawton, Michael, Tallantyre, Emma C., Robertson, Neil P.
Published in Annals of neurology (01.03.2024)
Published in Annals of neurology (01.03.2024)
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Journal Article
Multiple sclerosis risk variants influence the peripheral B‐cell compartment early in life in the general population
Mol, Casper L., Luijn, Marvin M., Kreft, Karim L., Looman, Kirsten I. M., Zelm, Menno C., White, Tonya, Moll, Henriette A., Smolders, Joost, Neuteboom, Rinze F.
Published in European journal of neurology (01.02.2023)
Published in European journal of neurology (01.02.2023)
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Journal Article
T cell composition and polygenic multiple sclerosis risk: A population‐based study in children
Mol, Casper L., Looman, Kirsten I. M., Luijn, Marvin M., Kreft, Karim L., Jansen, Philip R., Zelm, Menno C., Smolders, Joost J. F. M., White, Tonya J. H., Moll, Henriette A., Neuteboom, Rinze F.
Published in European journal of neurology (01.11.2021)
Published in European journal of neurology (01.11.2021)
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Journal Article
Elevated Expression of the Cerebrospinal Fluid Disease Markers Chromogranin A and Clusterin in Astrocytes of Multiple Sclerosis White Matter Lesions
van Luijn, Marvin M., van Meurs, Marjan, Stoop, Marcel P., Verbraak, Evert, Wierenga-Wolf, Annet F., Melief, Marie-José, Kreft, Karim L., Verdijk, Robert M., ’t Hart, Bert A., Luider, Theo M., Laman, Jon D., Hintzen, Rogier Q.
Published in Journal of neuropathology and experimental neurology (01.01.2016)
Published in Journal of neuropathology and experimental neurology (01.01.2016)
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Journal Article
EBNA-1 titer gradient in families with multiple sclerosis indicates a genetic contribution
Mescheriakova, Julia Y, van Nierop, Gijsbert P, van der Eijk, Annemiek A, Kreft, Karim L, Hintzen, Rogier Q
Published in Neurology : neuroimmunology & neuroinflammation (05.11.2020)
Published in Neurology : neuroimmunology & neuroinflammation (05.11.2020)
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Journal Article
The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis
Kreft, Karim L, Verbraak, Evert, Wierenga-Wolf, Annet F, van Meurs, Marjan, Oostra, Ben A, Laman, Jon D, Hintzen, Rogier Q
Published in The Journal of immunology (1950) (15.02.2012)
Published in The Journal of immunology (1950) (15.02.2012)
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Journal Article
Spinal cord involvement in Balo's concentric sclerosis
Kreft, Karim L, Mellema, S. Jouke, Hintzen, Rogier Q
Published in Journal of the neurological sciences (15.04.2009)
Published in Journal of the neurological sciences (15.04.2009)
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Journal Article
Abundant kif21b is associated with accelerated progression in neurodegenerative diseases
Kreft, Karim L, van Meurs, Marjan, Wierenga-Wolf, Annet F, Melief, Marie-Jose, van Strien, Miriam E, Hol, Elly M, Oostra, Ben A, Laman, Jon D, Hintzen, Rogier Q
Published in Acta neuropathologica communications (03.10.2014)
Published in Acta neuropathologica communications (03.10.2014)
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Journal Article
Cerebrospinal-fluid-derived Immunoglobulin G of Different Multiple Sclerosis Patients Shares Mutated Sequences in Complementarity Determining Regions
Singh, Vaibhav, Stoop, Marcel P., Stingl, Christoph, Luitwieler, Ronald L., Dekker, Lennard J., van Duijn, Martijn M., Kreft, Karim L., Luider, Theo M., Hintzen, Rogier Q.
Published in Molecular & cellular proteomics (01.12.2013)
Published in Molecular & cellular proteomics (01.12.2013)
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Journal Article
Role of CD8 regulatory T-cells in multiple sclerosis
Kreft, Karim L., Verbraak, Evert, Wierenga-Wolf, Annet F., Laman, Jon D., Hintzen, Rogier Q.
Published in Annals of neurology (01.03.2011)
Published in Annals of neurology (01.03.2011)
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Journal Article
MS-associated gene CLEC16A uses the molecular machinery of late endosomal biogenesis to control HLA-II expression in APC
Van Luijn, Marvin M, Kreft, Karim L, Jongsma, Marlieke L, Mes, Steven W, Wierenga-wolf, Annet F, Van Meurs, Marjan, Melief, Marie-josé, Van Der Kant, Rik, Janssen, Lennert, Janssen, Hans, Priatel, John J, Tan, Rusung, Neefjes, Jacques, Laman, Jon D, Hintzen, Rogier Q
Published in Journal of neuroimmunology (01.01.2014)
Published in Journal of neuroimmunology (01.01.2014)
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Journal Article