Targeting Lymphatic Vessel Activation and CCL21 Production by Vascular Endothelial Growth Factor Receptor-3 Inhibition Has Novel Immunomodulatory and Antiarteriosclerotic Effects in Cardiac Allografts
NYKÄNEN, Antti I, SANDELIN, Henrik, ALITALO, Kari, LEMSTRÖM, Karl B, KREBS, Rainer, KERÄNEN, Mikko A. I, TUUMINEN, Raimo, KÄRPÄNEN, Terhi, YAN WU, PYTOWSKI, Bronislaw, KOSKINEN, Petri K, YLÄ-HERTTUALA, Seppo
Published in Circulation (New York, N.Y.) (30.03.2010)
Published in Circulation (New York, N.Y.) (30.03.2010)
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Journal Article
Critical Role of VEGF-C/VEGFR-3 Signaling in Innate and Adaptive Immune Responses in Experimental Obliterative Bronchiolitis
Krebs, Rainer, Tikkanen, Jussi M, Ropponen, Jussi O, Jeltsch, Michael, Jokinen, Janne J, Ylä-Herttuala, Seppo, Nykänen, Antti I, Lemström, Karl B
Published in The American journal of pathology (01.11.2012)
Published in The American journal of pathology (01.11.2012)
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Journal Article
Donor Simvastatin Treatment Abolishes Rat Cardiac Allograft Ischemia/Reperfusion Injury and Chronic Rejection Through Microvascular Protection
TUUMINEN, Raimo, SYRJALA, Simo, KREBS, Rainer, KERÄNEN, Mikko A. I, KOLI, Katri, ABO-RAMADAN, Usama, NEUVONEN, Pertti J, TIKKANEN, Jussi M, NYKANEN, Antti I, LEMSTRÖM, Karl B
Published in Circulation (New York, N.Y.) (06.09.2011)
Published in Circulation (New York, N.Y.) (06.09.2011)
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Journal Article
Increased myeloid cell hypoxia-inducible factor-1 delays obliterative airway disease in the mouse
Ropponen, Jussi O., MD, Keränen, Mikko A., MD, PhD, Raissadati, Alireza, MD, Nykänen, Antti I., MD, PhD, Krebs, Rainer, MSc, PhD, Lemström, Karl B., MD, PhD, Tikkanen, Jussi M., MD, PhD
Published in The Journal of heart and lung transplantation (01.05.2016)
Published in The Journal of heart and lung transplantation (01.05.2016)
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Journal Article
Increased Th17 rather than Th1 alloimmune response is associated with cardiac allograft vasculopathy after hypothermic preservation in the rat
Syrjälä, Simo O., MD, Keränen, Mikko A.I., MD, Tuuminen, Raimo, MD, Nykänen, Antti I., MD, Tammi, Markku, MD, PhD, Krebs, Rainer, MS, Lemström, Karl B., MD, PhD
Published in The Journal of heart and lung transplantation (01.09.2010)
Published in The Journal of heart and lung transplantation (01.09.2010)
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Journal Article
Vascular Endothelial Growth Factor-B Overexpressing Hearts Are Not Protected From Transplant-Associated Ischemia-Reperfusion Injury
Raissadati, Alireza, Tuuminen, Raimo, Dashkevich, Alexey, Bry, Maija, Kivelä, Riikka, Anisimov, Andrey, Syrjälä, Simo, Arnaudova, Ralica, Rouvinen, Eeva, Keränen, Mikko Ai, Krebs, Rainer, Nykänen, Antti I, Lemström, Karl B
Published in Experimental and clinical transplantation (01.04.2017)
Published in Experimental and clinical transplantation (01.04.2017)
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Journal Article
Angiopoietin-1 protects against the development of cardiac allograft arteriosclerosis
NYKÄNEN, Antti I, KREBS, Rainer, SAARISTO, Anne, TURUNEN, Päivi, ALITALO, Kari, YLÄ-HERTTUALA, Seppo, KOSKINEN, Petri K, LEMSTRÖM, Karl B
Published in Circulation (New York, N.Y.) (11.03.2003)
Published in Circulation (New York, N.Y.) (11.03.2003)
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Journal Article
Innate and adaptive immune responses in obliterative airway disease in rat tracheal allografts
Ropponen, Jussi O., MD, Syrjälä, Simo O., MD, Krebs, Rainer, MSc, Nykänen, Antti, MD, PhD, Tikkanen, Jussi M., MD, PhD, Lemström, Karl B., MD, PhD
Published in The Journal of heart and lung transplantation (01.06.2011)
Published in The Journal of heart and lung transplantation (01.06.2011)
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Journal Article
Effect of simvastatin on development of obliterative airway disease: An experimental study
Ropponen, Jussi O., MD, Syrjälä, Simo O., MD, Hollmén, Maria, MD, Tuuminen, Raimo, MD, Krebs, Rainer, MD, Keränen, Mikko A., MD, Vaali, Kirsi, MD, Nykänen, Antti I., MD, PhD, Lemström, Karl B., MD, PhD, Tikkanen, Jussi M., MD, PhD
Published in The Journal of heart and lung transplantation (01.02.2012)
Published in The Journal of heart and lung transplantation (01.02.2012)
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Journal Article
Cardiomyocyte-targeted HIF-1α gene therapy inhibits cardiomyocyte apoptosis and cardiac allograft vasculopathy in the rat
Keränen, Mikko A.I., MD, Nykänen, Antti I., MD, PhD, Krebs, Rainer, MSc, Pajusola, Katri, PhD, Tuuminen, Raimo, MD, Alitalo, Kari, MD, PhD, Lemström, Karl B., MD, PhD
Published in The Journal of heart and lung transplantation (2010)
Published in The Journal of heart and lung transplantation (2010)
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Journal Article
Common Protective and Diverse Smooth Muscle Cell Effects of AAV-Mediated Angiopoietin-1 and -2 Expression in Rat Cardiac Allograft Vasculopathy
Nykänen, Antti I, Pajusola, Katri, Krebs, Rainer, Keränen, Mikko A.I, Raisky, Olivier, Koskinen, Petri K, Alitalo, Kari, Lemström, Karl B
Published in Circulation research (09.06.2006)
Published in Circulation research (09.06.2006)
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Journal Article
VEGFR-1 and -2 Regulate Inflammation, Myocardial Angiogenesis, and Arteriosclerosis in Chronically Rejecting Cardiac Allografts
Raisky, Olivier, Nykänen, Antti I, Krebs, Rainer, Hollmén, Maria, Keränen, Mikko A.I, Tikkanen, Jussi M, Sihvola, Roope, Alhonen, Leena, Salven, Petri, Wu, Yan, Hicklin, Daniel J, Alitalo, Kari, Koskinen, Petri K, Lemström, Karl B
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2007)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2007)
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Journal Article
Embedded Digital Twins in future energy management systems: paving the way for automated grid control
Brosinsky, Christoph, Krebs, Rainer, Westermann, Dirk
Published in Automatisierungstechnik : AT (25.09.2020)
Published in Automatisierungstechnik : AT (25.09.2020)
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Journal Article
Hybrid fuzzy evaluation algorithm for power system protection security assessment
Meyer, Georg Janick, Lorz, Tobias, Wehner, Rene, Jaeger, Johann, Dauer, Maximilian, Krebs, Rainer
Published in Electric power systems research (01.12.2020)
Published in Electric power systems research (01.12.2020)
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Journal Article
Inhibition of Vascular Endothelial Growth Factor Receptors 1 and 2 Attenuates Natural Killer Cell and Innate Immune Responses in an Experimental Model for Obliterative Bronchiolitis
Krebs, Rainer, Tikkanen, Jussi M., Raissadati, Alireza, Hollmén, Maria, Dhaygude, Kishor, Lemström, Karl B.
Published in The American journal of pathology (01.02.2022)
Published in The American journal of pathology (01.02.2022)
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Journal Article
Donor plasma VEGF-A as a biomarker for myocardial injury and primary graft dysfunction after heart transplantation
Holmström, Emil J., Syrjälä, Simo O., Dhaygude, Kishor, Tuuminen, Raimo, Krebs, Rainer, Lommi, Jyri, Nykänen, Antti, Lemström, Karl B.
Published in The Journal of heart and lung transplantation (01.10.2024)
Published in The Journal of heart and lung transplantation (01.10.2024)
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Journal Article
Severe primary graft dysfunction of the heart transplant is associated with increased plasma and intragraft proinflammatory cytokine expression
Holmström, Emil J., Syrjälä, Simo O., Dhaygude, Kishor, Tuuminen, Raimo, Krebs, Rainer, Nykänen, Antti, Lemström, Karl B.
Published in The Journal of heart and lung transplantation (01.06.2023)
Published in The Journal of heart and lung transplantation (01.06.2023)
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Journal Article
Structured controller parameter tuning for power systems
Mešanović, Amer, Münz, Ulrich, Szabo, Andrei, Mangold, Martin, Bamberger, Joachim, Metzger, Michael, Heyde, Chris, Krebs, Rainer, Findeisen, Rolf
Published in Control engineering practice (01.08.2020)
Published in Control engineering practice (01.08.2020)
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Journal Article
Donor Simvastatin Treatment in Heart Transplantation: A Randomized and Blinded Clinical Trial
Nykänen, Antti I, Holmström, Emil J, Tuuminen, Raimo, Krebs, Rainer, Dhaygude, Kishor, Kankainen, Matti, Jokinen, Janne J, Lommi, Jyri, Helanterä, Ilkka, Räisänen-Sokolowski, Anne, Syrjälä, Simo O, Lemström, Karl B
Published in Circulation (New York, N.Y.) (20.08.2019)
Published in Circulation (New York, N.Y.) (20.08.2019)
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Journal Article