BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
Maxwell, Kara N, Wubbenhorst, Bradley, Wenz, Brandon M, De Sloover, Daniel, Pluta, John, Emery, Lyndsey, Barrett, Amanda, Kraya, Adam A, Anastopoulos, Ioannis N, Yu, Shun, Jiang, Yuchao, Chen, Hao, Zhang, Nancy R, Hackman, Nicole, D'Andrea, Kurt, Daber, Robert, Morrissette, Jennifer J D, Mitra, Nandita, Feldman, Michael, Domchek, Susan M, Nathanson, Katherine L
Published in Nature communications (22.08.2017)
Published in Nature communications (22.08.2017)
Get full text
Journal Article
Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer
Kraya, Adam A, Maxwell, Kara N, Wubbenhorst, Bradley, Wenz, Brandon M, Pluta, John, Rech, Andrew J, Dorfman, Liza M, Lunceford, Nicole, Barrett, Amanda, Mitra, Nandita, Morrissette, Jennifer J D, Feldman, Michael, Nayak, Anupma, Domchek, Susan M, Vonderheide, Robert H, Nathanson, Katherine L
Published in Clinical cancer research (15.07.2019)
Published in Clinical cancer research (15.07.2019)
Get full text
Journal Article
Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers
Shah, Jennifer B, Pueschl, Dana, Wubbenhorst, Bradley, Fan, Mengyao, Pluta, John, D'Andrea, Kurt, Hubert, Anna P, Shilan, Jake S, Zhou, Wenting, Kraya, Adam A, Llop Guevara, Alba, Ruan, Catherine, Serra, Violeta, Balmaña, Judith, Feldman, Michael, Morin, Pat J, Nayak, Anupma, Maxwell, Kara N, Domchek, Susan M, Nathanson, Katherine L
Published in Nature communications (07.11.2022)
Published in Nature communications (07.11.2022)
Get full text
Journal Article
A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma
Huang, Alexander C, Orlowski, Robert J, Xu, Xiaowei, Mick, Rosemarie, George, Sangeeth M, Yan, Patrick K, Manne, Sasikanth, Kraya, Adam A, Wubbenhorst, Bradley, Dorfman, Liza, D'Andrea, Kurt, Wenz, Brandon M, Liu, Shujing, Chilukuri, Lakshmi, Kozlov, Andrew, Carberry, Mary, Giles, Lydia, Kier, Melanie W, Quagliarello, Felix, McGettigan, Suzanne, Kreider, Kristin, Annamalai, Lakshmanan, Zhao, Qing, Mogg, Robin, Xu, Wei, Blumenschein, Wendy M, Yearley, Jennifer H, Linette, Gerald P, Amaravadi, Ravi K, Schuchter, Lynn M, Herati, Ramin S, Bengsch, Bertram, Nathanson, Katherine L, Farwell, Michael D, Karakousis, Giorgos C, Wherry, E John, Mitchell, Tara C
Published in Nature medicine (01.03.2019)
Published in Nature medicine (01.03.2019)
Get full text
Journal Article
Association of Filaggrin Loss-of-Function Variants With Race in Children With Atopic Dermatitis
Margolis, David J, Mitra, Nandita, Wubbenhorst, Bradley, D'Andrea, Kurt, Kraya, Adam A, Hoffstad, Ole, Shah, Saloni, Nathanson, Katherine L
Published in JAMA dermatology (Chicago, Ill.) (01.11.2019)
Published in JAMA dermatology (Chicago, Ill.) (01.11.2019)
Get more information
Journal Article
Identification of secreted proteins that reflect autophagy dynamics within tumor cells
Kraya, Adam A., Piao, Shengfu, Xu, Xiaowei, Zhang, Gao, Herlyn, Meenhard, Gimotty, Phyllis, Levine, Beth, Amaravadi, Ravi K, Speicher, David W
Published in Autophagy (01.01.2015)
Published in Autophagy (01.01.2015)
Get full text
Journal Article
PTEN Loss and BRCA1 Promoter Hypermethylation Negatively Predict for Immunogenicity in BRCA-Deficient Ovarian Cancer
Kraya, Adam A, Maxwell, Kara N, Eiva, Monika A, Wubbenhorst, Bradley, Pluta, John, Feldman, Michael, Nayak, Anupma, Powell, Jr, Daniel J, Domchek, Susan M, Vonderheide, Robert H, Nathanson, Katherine L
Published in JCO precision oncology (01.02.2022)
Published in JCO precision oncology (01.02.2022)
Get more information
Journal Article
The Open Pediatric Cancer Project
Geng, Zhuangzhuang, Wafula, Eric, Corbett, Ryan J, Zhang, Yuanchao, Jin, Run, Gaonkar, Krutika S, Shukla, Sangeeta, Rathi, Komal S, Hill, Dave, Lahiri, Aditya, Miller, Daniel P, Sickler, Alex, Keith, Kelsey, Blackden, Christopher, Chroni, Antonia, Brown, Miguel A, Kraya, Adam A, Koschmann, Carl J, Aldape, Kenneth, Huang, Xiaoyan, Rood, Brian R, Mason, Jennifer L, Trooskin, Gerri R, Abdullaev, Zied, Wang, Pei, Zhu, Yuankun, Farrow, Bailey K, Farrel, Alvin, Dybas, Joseph M, Zhong, Chuwei, Kuren, Nicholas Van, Zhang, Bo, Santi, Mariarita, Phul, Saksham, Chinwalla, Asif T, Resnick, Adam C, Diskin, Sharon J, Tasian, Sarah, Stefankiewicz, Stephanie, Maris, John M, Ennis, Brian M, Lueder, Matthew R, Naqvi, Ammar S, Coleman, Noel, Ma, Weiping, Taylor, Deanne, Rokita, Jo Lynne
Published in bioRxiv (11.07.2024)
Published in bioRxiv (11.07.2024)
Get full text
Journal Article
TMET-29. THE GLUTAMINE TRANSPORTER SLC1A5 IS ASSOCIATED WITH REWIRING OF AMINO ACID, LIPID, AND IMMUNE PATHWAYS AND TUMOR PROGNOSIS IN PEDIATRIC BRAIN CANCERS
Kraya, Adam A, Jin, Run, Zhao, Chao, Familiar, Ariana, Storm, Philip B, Wellen, Kathryn, Resnick, Adam C, Nabavizadeh, Ali
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Get full text
Journal Article
HGG-32. PNOC008: A PILOT TRIAL TESTING THE CLINICAL BENEFIT OF USING MOLECULAR PROFILING TO DETERMINE AN INDIVIDUALIZED TREATMENT PLAN IN CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMA (EXCLUDING DIFFUSE INTRINSIC PONTINE GLIOMA)
Franson, Andrea T, Kilburn, Lindsay B, Cooney, Tab M, Stoller, Schuyler, Reddy, Alyssa T, Banerjee, Anu, Packer, Roger J, Bendel, Anne E, Skrypek, Mary M, Minturn, Jane E, Abdelbaki, Mohamed S, Whipple, Nicholas S, Chan, Priya, Crawford, John R, Crotty, Erin E, Waanders, Angela J, Elster, Jennifer D, Raabe, Eric H, George, Elizabeth, Pinto, Soniya N, Vossough, Arastoo, Kraya, Adam A, Prados, Michael, Kline, Cassie, Nazarian, Javad, Solomon, David A, Long-Boyle, Janel R, Molinaro, Annette M, Waszak, Sebastian M, Mueller, Sabine
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Get full text
Journal Article
NIMG-74. RADIOIMMUNOMIC SIGNATURES IN PEDIATRIC LOW-GRADE GLIOMA BASED ON MULTIPARAMETRIC MRI SCANS
Kazerooni, Anahita Fathi, Kraya, Adam A, Kim, Meen Chul, Khalili, Nastaran, Arif, Sherjeel, Jin, Run, Rathi, Komal, Familiar, Ariana, Madhogarhia, Rachel, Haldar, Debanjan, Bagheri, Sina, Anderson, Hannah, Shaikh, Ibraheem Salman, Haldar, Shuvanjan, Ware, Jeffrey B, Vossough, Arastoo, Storm, Philip B, Resnick, Adam C, Davatzikos, Christos, Nabavizadeh, Ali
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Get full text
Journal Article
Abstract 4889: Integrative multi-omic analysis reveals novel prognostic biological entities in pediatric medulloblastoma
Rathi, Komal, Kesherwani, Varun, Naqvi, Ammar S., Zhu, Yuankun, Sickler, Alex, Huang, Xiaoyan, Zhang, Bo, Rood, Brian, Resnick, Adam C., Kraya, Adam A.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract A22: Homologous recombination deficiency negatively predicts for immune infiltration and antitumor immune activity in breast tumors with BRCA1/2 alterations
Kraya, Adam A., Maxwell, Kara N., Wubbenhorst, Bradley, Wenz, Brandon M., Pluta, John, Rech, Andrew J., Lunceford, Nicole, Barrett, Amanda, Mitra, Nandita, Morrissette, Jennifer J.D., Nayak, Anupma, Feldman, Michael, Domchek, Susan M., Vonderheide, Robert H., Nathanson, Katherine L.
Published in Molecular cancer research (01.08.2018)
Published in Molecular cancer research (01.08.2018)
Get full text
Journal Article
Abstract 2725: Molecular mechanisms of aberrant splicing in pediatric high grade gliomas
Naqvi, Ammar S., Ennis, Brian, Jin, Run, Conkrite, Karina L., Rathi, Komal S., Kraya, Adam A., Sonawane, Poonam, Storm, Phillip B., Resnick, Adam C., Rokita, Jo Lynne
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 4511: Characterization of tumor neoantigen repertoire in patients with germline BRCA12 mutations
Kraya, Adam A, Maxwell, Kara N, Wenz, Brandon M, Wubbenhorst, Bradley, DeSloover, Daniel, Lunceford, Nicole, Morrissette, Jennifer D, Feldman, Michael, Vonderheide, Robert H, Domchek, Susan M, Nathanson, Katherine L
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Get full text
Journal Article
Abstract 4511: Characterization of tumor neoantigen repertoire in patients with germline BRCA1/2 mutations
Kraya, Adam A., Maxwell, Kara N., Wenz, Brandon M., Wubbenhorst, Bradley, DeSloover, Daniel, Lunceford, Nicole, Morrissette, Jennifer D., Feldman, Michael, Vonderheide, Robert H., Domchek, Susan M., Nathanson, Katherine L.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Get full text
Journal Article
Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency
Naqvi, Ammar S, Corbett, Ryan J, Seghal, Priyanka, Conkrite, Karina L, Rathi, Komal S, Ennis, Brian M, Hayer, Katharina E, Zhang, Bo, Brown, Miguel A, Miller, Daniel P, Kraya, Adam A, Dybas, Joseph M, Geng, Zhuangzhuang, Blackden, Christopher, Arif, Shehbeel, Chroni, Antonia, Lahiri, Aditya, Hollawell, Madison L, Storm, Phillip B, Foster, Jessica B, Koptyra, Mateusz, Madsen, Peter J, Diskin, Sharon J, Thomas-Tikhonenko, Andrei, Resnick, Adam C, Rokita, Jo Lynne
Published in bioRxiv (22.08.2024)
Published in bioRxiv (22.08.2024)
Get full text
Journal Article
The splicing modulator CLK1 is a candidate oncogenic dependency in pediatric high-grade gliomas
Naqvi, Ammar S., Corbett, Ryan J., Seghal, Priyanka, Conkrite, Karina L., Rathi, Komal S., Ennis, Brian M., Hayer, Katharina E, Zhang, Bo, Brown, Miguel A., Miller, Daniel P., Kraya, Adam A., Dybas, Joseph M., Geng, Zhuangzhuang, Blackden, Christopher, Arif, Shehbeel, Chroni, Antonia, Lahiri, Aditya, Hollawell, Madison L., Storm, Phillip B., Foster, Jessica B., Koptyra, Mateusz, Madsen, Peter J., Diskin, Sharon J., Thomas-Tikhonenko, Andrei, Resnick, Adam C., Rokita, Jo Lynne
Published in bioRxiv (06.08.2024)
Published in bioRxiv (06.08.2024)
Get full text
Journal Article