Combination of the novel BET inhibitor BI 894999 with CDK9 inhibition suggests a promising regimen for the treatment of AML
Tontsch-Grunt, U, Savarese, F, Baum, A, Scharn, D, Gerlach, D, Hofmann, M.H, Popow, J, Schweifer, N, Engelhardt, H, Musa, H, Lee, C.P, Munzert, G.M, Kraut, N
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Journal Article
Molecular requirements for epithelial–mesenchymal transition during tumor progression
Huber, Margit A, Kraut, Norbert, Beug, Hartmut
Published in Current opinion in cell biology (01.10.2005)
Published in Current opinion in cell biology (01.10.2005)
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Journal Article
136 (PB124): Zongertinib (BI1810631), an irreversible HER2 TKI spares EGFR signaling and improves therapeutic response in preclinical models and patients with HER2-driven cancers
Neumueller, R., Wilding, B., Augsten, M., Baum, A., Chylinski, K., Waizenegger, I., Woelflingseder, L., Solca, F., Kraut, N.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
100 (PB088): KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harboring KRASG12V mutations and KRAS wild-type amplifications
Tedeschi, A., Peng, D.H., Schischlik-Siegl, F., Schaaf, O., Gerlach, D., Rocchetti, F., Popow, J., Broeker, J., Wunberg, T., Boghossian, A.S., Rees, M.G., Ronan, M.M., Roth, J.A., Williams, M., Vellano, C., Marszalek, J.R., Heffernan, T.P., Pearson, M., Kraut, N., Dorothea, R.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
210 (PB198): KRASmulti inhibition and checkpoint targeting therapy show strong combination potential in KRAS wild-type and KRASG12V-driven syngeneic mouse models of pancreatic cancer
Ebner, F., Krolo, A., Artemov, A., Hubmann, M., Hajto, A., Oslislok, M., Baumann, I., Egermann, W., Chylinski, K., Tedeschi, A., Lipp, J., Kraut, N., Pearson, M., Pisarsky, L., Rudolph, D., Aichinger, M.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
Huber, Margit A., Azoitei, Ninel, Baumann, Bernd, Grünert, Stefan, Sommer, Andreas, Pehamberger, Hubert, Kraut, Norbert, Beug, Hartmut, Wirth, Thomas
Published in The Journal of clinical investigation (16.08.2004)
Published in The Journal of clinical investigation (16.08.2004)
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Journal Article
126 (PB114): A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer
Jung, P., Glaser, S.P., Han, J., Popa, A., Pisarsky, L., Feng, N., Geyer, A., Haderk, F., Alpar, D., Bristow, C., Drobits-Handl, B., Kasturirangan, S., Trapani, F., Marszalek, J.R., Tontsch-Grunt, U., Pearson, M., Heffernan, T.P., Kraut, N., Vellano, C.P., García-Martínez, J.M.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Journal Article
BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo
Steegmaier, Martin, Hoffmann, Matthias, Baum, Anke, Lénárt, Péter, Petronczki, Mark, Krššák, Martin, Gürtler, Ulrich, Garin-Chesa, Pilar, Lieb, Simone, Quant, Jens, Grauert, Matthias, Adolf, Günther R., Kraut, Norbert, Peters, Jan-Michael, Rettig, Wolfgang J.
Published in Current biology (20.02.2007)
Published in Current biology (20.02.2007)
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Journal Article
Vertical pathway inhibition with a SOS1::KRAS inhibitor enhances the efficacy of KRAS G12C inhibitors, delays feedback resistance and demonstrates durable response
Savarese, F., Gmachl, M., Federico, L., Trapani, F., Gerlach, D., Daniele, J., Feng, N., Bristow, C.A., Machado, A., Huang, J., Rudolph, D., Waizenegger, I., Ramharter, J., Vellano, C.P., Petronczki, M., Marszalek, J.R., Heffernan, T.P., McConnell, D.B., Kraut, N., Hofmann, M.
Published in European journal of cancer (1990) (01.10.2020)
Published in European journal of cancer (1990) (01.10.2020)
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Journal Article
Microarray Gene Expression Profiling of B-Cell Chronic Lymphocytic Leukemia Subgroups Defined by Genomic Aberrations and VH Mutation Status
HASLINGER, Christian, SCHWEIFER, Norbert, STILGENBAUER, Stephan, DÖHNER, Hartmut, LICHTER, Peter, KRAUT, Norbert, STRATOWA, Christian, ABSEHER, Roger
Published in Journal of clinical oncology (01.10.2004)
Published in Journal of clinical oncology (01.10.2004)
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Journal Article
Expression profiling of epithelial plasticity in tumor progression
JECHLINGER, Martin, GRUNERT, Stefan, TAMIR, Ido H, JANDA, Elzbieta, LÜDEMANN, Susanna, WAERNER, Thomas, SEITHER, Peter, WEITH, Andreas, BEUG, Hartmut, KRAUT, Norbert
Published in Oncogene (16.10.2003)
Published in Oncogene (16.10.2003)
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Journal Article
Regulation of yeast COX6 by the general transcription factor ABF1 and separate HAP2- and heme-responsive elements
TRAWICK, J. D, KRAUT, N, SIMON, F. R, POYTON, R. O
Published in Molecular and Cellular Biology (01.05.1992)
Published in Molecular and Cellular Biology (01.05.1992)
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Journal Article
A highly selective telomerase inhibitor limiting human cancer cell proliferation
Damm, Klaus, Hemmann, Ulrike, Garin-Chesa, Pilar, Hauel, Norbert, Kauffmann, Iris, Priepke, Henning, Niestroj, Claudia, Daiber, Christine, Enenkel, Barbara, Guilliard, Bernd, Lauritsch, Ines, Müller, Elfriede, Pascolo, Emanuelle, Sauter, Gabriele, Pantic, Milena, Martens, Uwe M., Wenz, Christian, Lingner, Joachim, Kraut, Norbert, Rettig, Wolfgang J., Schnapp, Andreas
Published in The EMBO journal (17.12.2001)
Published in The EMBO journal (17.12.2001)
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Journal Article
Fibroblast Activation Protein: Differential Expression and Serine Protease Activity in Reactive Stromal Fibroblasts of Melanocytic Skin Tumors
Huber, Margit A., Schubert, Roland D., Peter, Ralf U., Kraut, Norbert, Park, John E., Rettig, Wolfgang J., Garin-Chesa, Pilar
Published in Journal of investigative dermatology (01.02.2003)
Published in Journal of investigative dermatology (01.02.2003)
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Journal Article
Porous Nanostructured Encapsulation and Immobilization Materials for Optical Biosensors
Cheung, M. C., Ka Yi Yung, Huina Xu, Kraut, N. D., Ke Liu, Chodavarapu, V. P., Cartwright, A. N., Bright, F. V.
Published in IEEE journal of selected topics in quantum electronics (01.05.2012)
Published in IEEE journal of selected topics in quantum electronics (01.05.2012)
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