ACU193: An Immunotherapeutic Poised to Test the Amyloid β Oligomer Hypothesis of Alzheimer's Disease
Krafft, Grant A, Jerecic, Jasna, Siemers, Eric, Cline, Erika N
Published in Frontiers in neuroscience (26.04.2022)
Published in Frontiers in neuroscience (26.04.2022)
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Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss
Gong, Yuesong, Chang, Lei, Viola, Kirsten L., Lacor, Pascale N., Lambert, Mary P., Finch, Caleb E., Krafft, Grant A., Klein, William L.
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2003)
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Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein
Kim, Hyeon-Jin, Chae, Soo-Cheon, Lee, Dae-Kwon, Chromy, Brett, Lee, Sam Cheol, Park, Yeong-Chul, Klein, William L, Krafft, Grant A, Hong, Seong-Tshool
Published in The FASEB journal (01.01.2003)
Published in The FASEB journal (01.01.2003)
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Monoclonal antibodies that target pathological assemblies of Aβ
Lambert, Mary P, Velasco, Pauline T, Chang, Lei, Viola, Kirsten L, Fernandez, Sara, Lacor, Pascale N, Khuon, Daliya, Gong, Yuesong, Bigio, Eileen H, Shaw, Pamela, De Felice, Fernanda G, Krafft, Grant A, Klein, William L
Published in Journal of neurochemistry (2007)
Published in Journal of neurochemistry (2007)
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An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging
Wang, Xueying, Kastanenka, Ksenia V., Arbel-Ornath, Michal, Commins, Caitlin, Kuzuya, Akira, Lariviere, Amanda J., Krafft, Grant A., Hefti, Franz, Jerecic, Jasna, Bacskai, Brian J.
Published in Scientific reports (15.03.2018)
Published in Scientific reports (15.03.2018)
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Synaptic targeting by Alzheimer's-related amyloid beta oligomers
Lacor, Pascale N, Buniel, Maria C, Chang, Lei, Fernandez, Sara J, Gong, Yuesong, Viola, Kirsten L, Lambert, Mary P, Velasco, Pauline T, Bigio, Eileen H, Finch, Caleb E, Krafft, Grant A, Klein, William L
Published in The Journal of neuroscience (10.11.2004)
Published in The Journal of neuroscience (10.11.2004)
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Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?
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Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-β oligomers
Gandy, Sam, Simon, Adam J., Steele, John W., Lublin, Alex L., Lah, James J., Walker, Lary C., Levey, Allan I., Krafft, Grant A., Levy, Efrat, Checler, Frédéric, Glabe, Charles, Bilker, Warren B., Abel, Ted, Schmeidler, James, Ehrlich, Michelle E.
Published in Annals of neurology (01.08.2010)
Published in Annals of neurology (01.08.2010)
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Self-Assembly of Aβ1 - 42 into Globular Neurotoxins
Chromy, Brett A, Nowak, Richard J, Lambert, Mary P, Viola, Kirsten L, Chang, Lei, Velasco, Pauline T, Jones, Bryan W, Fernandez, Sara J, Lacor, Pascale N, Horowitz, Peleg, Finch, Caleb E, Krafft, Grant A, Klein, William L
Published in Biochemistry (Easton) (11.11.2003)
Published in Biochemistry (Easton) (11.11.2003)
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Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
Wang, Hai-Wei, Pasternak, Joseph F, Kuo, Helen, Ristic, Helen, Lambert, Mary P, Chromy, Brett, Viola, Kirsten L, Klein, William L, Stine, W.Blaine, Krafft, Grant A, Trommer, Barbara L
Published in Brain research (11.01.2002)
Published in Brain research (11.01.2002)
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Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies
Lambert, Mary P., Viola, Kirsten L., Chromy, Brett A., Chang, Lei, Morgan, Todd E., Yu, Jiaxin, Venton, Duane L., Krafft, Grant A., Finch, Caleb E., Klein, William L.
Published in Journal of neurochemistry (01.11.2001)
Published in Journal of neurochemistry (01.11.2001)
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