Drugging the HDAC6–HSP90 interplay in malignant cells
Krämer, Oliver H, Mahboobi, Siavosh, Sellmer, Andreas
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2014)
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2014)
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Journal Article
Interstrand Crosslink Repair as a Target for HDAC Inhibition
Nikolova, Teodora, Kiweler, Nicole, Krämer, Oliver H.
Published in Trends in pharmacological sciences (Regular ed.) (01.09.2017)
Published in Trends in pharmacological sciences (Regular ed.) (01.09.2017)
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Journal Article
Concepts to Target MYC in Pancreatic Cancer
Wirth, Matthias, Mahboobi, Siavosh, Krämer, Oliver H, Schneider, Günter
Published in Molecular cancer therapeutics (01.08.2016)
Published in Molecular cancer therapeutics (01.08.2016)
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Journal Article
Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis
Wagner, Tobias, Brand, Peter, Heinzel, Thorsten, Krämer, Oliver H.
Published in Biochimica et biophysica acta (01.12.2014)
Published in Biochimica et biophysica acta (01.12.2014)
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Journal Article
Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis
Korfei, Martina, Stelmaszek, Daniel, MacKenzie, BreAnne, Skwarna, Sylwia, Chillappagari, Shashipavan, Bach, Anna C, Ruppert, Clemens, Saito, Shigeki, Mahavadi, Poornima, Klepetko, Walter, Fink, Ludger, Seeger, Werner, Lasky, Joseph A, Pullamsetti, Soni S, Krämer, Oliver H, Guenther, Andreas
Published in PloS one (27.11.2018)
Published in PloS one (27.11.2018)
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Journal Article
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors
Sellmer, Andreas, Stangl, Hubert, Beyer, Mandy, Grünstein, Elisabeth, Leonhardt, Michel, Pongratz, Herwig, Eichhorn, Emerich, Elz, Sigurd, Striegl, Birgit, Jenei-Lanzl, Zsuzsa, Dove, Stefan, Straub, Rainer H, Krämer, Oliver H, Mahboobi, Siavosh
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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Journal Article
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor
Bröker, Joachim, Waterson, Alex G., Smethurst, Chris, Kessler, Dirk, Böttcher, Jark, Mayer, Moriz, Gmaschitz, Gerhard, Phan, Jason, Little, Andrew, Abbott, Jason R., Sun, Qi, Gmachl, Michael, Rudolph, Dorothea, Arnhof, Heribert, Rumpel, Klaus, Savarese, Fabio, Gerstberger, Thomas, Mischerikow, Nikolai, Treu, Matthias, Herdeis, Lorenz, Wunberg, Tobias, Gollner, Andreas, Weinstabl, Harald, Mantoulidis, Andreas, Krämer, Oliver, McConnell, Darryl B., W. Fesik, Stephen
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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Journal Article
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia
Toutah, Krimo, Nawar, Nabanita, Timonen, Sanna, Sorger, Helena, Raouf, Yasir S, Bukhari, Shazreh, von Jan, Jana, Ianevski, Aleksandr, Gawel, Justyna M, Olaoye, Olasunkanmi O, Geletu, Mulu, Abdeldayem, Ayah, Israelian, Johan, Radu, Tudor B, Sedighi, Abootaleb, Bhatti, Muzaffar N, Hassan, Muhammad Murtaza, Manaswiyoungkul, Pimyupa, Shouksmith, Andrew E, Neubauer, Heidi A, de Araujo, Elvin D, Aittokallio, Tero, Krämer, Oliver H, Moriggl, Richard, Mustjoki, Satu, Herling, Marco, Gunning, Patrick T
Published in Journal of medicinal chemistry (24.06.2021)
Published in Journal of medicinal chemistry (24.06.2021)
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Journal Article
HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130
Göder, Anja, Emmerich, Claudia, Nikolova, Teodora, Kiweler, Nicole, Schreiber, Maria, Kühl, Toni, Imhof, Diana, Christmann, Markus, Heinzel, Thorsten, Schneider, Günter, Krämer, Oliver H.
Published in Nature communications (22.02.2018)
Published in Nature communications (22.02.2018)
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Journal Article
Survivin and YM155: How faithful is the liaison?
Rauch, Anke, Hennig, Dorle, Schäfer, Claudia, Wirth, Matthias, Marx, Christian, Heinzel, Thorsten, Schneider, Günter, Krämer, Oliver H.
Published in Biochimica et biophysica acta (01.04.2014)
Published in Biochimica et biophysica acta (01.04.2014)
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Journal Article
Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance
Krumm, Andrea, Barckhausen, Christina, Kücük, Pelin, Tomaszowski, Karl-Heinz, Loquai, Carmen, Fahrer, Jörg, Krämer, Oliver Holger, Kaina, Bernd, Roos, Wynand Paul
Published in Cancer research (Chicago, Ill.) (15.05.2016)
Published in Cancer research (Chicago, Ill.) (15.05.2016)
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Journal Article
Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins
Halilovic, Melisa, Abdelsalam, Mohamed, Zabkiewicz, Joanna, Lazenby, Michelle, Alvares, Caroline, Schmidt, Matthias, Brenner, Walburgis, Najafi, Sara, Oehme, Ina, Hieber, Christoph, Zeyn, Yanira, Bros, Matthias, Sippl, Wolfgang, Krämer, Oliver H
Published in Leukemia (17.09.2024)
Published in Leukemia (17.09.2024)
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Journal Article