Mitogen-Activated Protein Kinases Promote WNT/β-Catenin Signaling via Phosphorylation of LRP6
Červenka, Igor, Wolf, Joshua, Mašek, Jan, Krejci, Pavel, Wilcox, William R, Kozubík, Alois, Schulte, Gunnar, Gutkind, J Silvio, Bryja, Vítězslav
Published in Molecular and Cellular Biology (01.01.2011)
Published in Molecular and Cellular Biology (01.01.2011)
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Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation
Tylichová, Zuzana, Straková, Nicol, Vondráček, Jan, Vaculová, Alena Hyršlová, Kozubík, Alois, Hofmanová, Jiřina
Published in The Journal of nutritional biochemistry (01.01.2017)
Published in The Journal of nutritional biochemistry (01.01.2017)
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Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells
Herůdková, Jarmila, Paruch, Kamil, Khirsariya, Prashant, Souček, Karel, Krkoška, Martin, Vondálová Blanářová, Olga, Sova, Petr, Kozubík, Alois, Hyršlová Vaculová, Alena
Published in Neoplasia (New York, N.Y.) (01.10.2017)
Published in Neoplasia (New York, N.Y.) (01.10.2017)
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Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of polycyclic aromatic hydrocarbons
Andrysík, Zdeněk, Vondráček, Jan, Marvanová, Soňa, Ciganek, Miroslav, Neča, Jiří, Pěnčíková, Kateřina, Mahadevan, Brinda, Topinka, Jan, Baird, William M, Kozubík, Alois, Machala, Miroslav
Published in Mutation research (01.09.2011)
Published in Mutation research (01.09.2011)
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Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models
Zapletal, Ondřej, Tylichová, Zuzana, Neča, Jiří, Kohoutek, Jiří, Machala, Miroslav, Milcová, Alena, Pokorná, Michaela, Topinka, Jan, Moyer, Mary Pat, Hofmanová, Jiřina, Kozubík, Alois, Vondráček, Jan
Published in Archives of toxicology (01.05.2017)
Published in Archives of toxicology (01.05.2017)
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Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10
Vondálová Blanářová, Olga, Šafaříková, Barbora, Herůdková, Jarmila, Krkoška, Martin, Tománková, Silvie, Kahounová, Zuzana, Anděra, Ladislav, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Sova, Petr, Kozubík, Alois, Hyršlová Vaculová, Alena
Published in PloS one (28.11.2017)
Published in PloS one (28.11.2017)
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Butyrate interacts with benzo[a]pyrene to alter expression and activities of xenobiotic metabolizing enzymes involved in metabolism of carcinogens within colon epithelial cell models
Zapletal, Ondřej, Procházková, Jiřina, Dubec, Vít, Hofmanová, Jiřina, Kozubík, Alois, Vondráček, Jan
Published in Toxicology (Amsterdam) (15.01.2019)
Published in Toxicology (Amsterdam) (15.01.2019)
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Interaction of Dietary Fatty Acids with Tumour Necrosis Factor Family Cytokines during Colon Inflammation and Cancer
Hofmanova, Jirina, Strakova, Nicol, Vaculova, Alena Hyrslova, Tylichova, Zuzana, Safarikova, Barbora, Skender, Belma, Kozubik, Alois
Published in Mediators of Inflammation (01.01.2014)
Published in Mediators of Inflammation (01.01.2014)
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Androgen Depletion Induces Senescence in Prostate Cancer Cells through Down-regulation of Skp2
Pernicová, Zuzana, Slabáková, Eva, Kharaishvili, Gvantsa, Bouchal, Jan, Král, Milan, Kunická, Zuzana, Machala, Miroslav, Kozubík, Alois, Součcek, Karel
Published in Neoplasia (New York, N.Y.) (01.06.2011)
Published in Neoplasia (New York, N.Y.) (01.06.2011)
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Interactive effects of inflammatory cytokine and abundant low-molecular-weight PAHs on inhibition of gap junctional intercellular communication, disruption of cell proliferation control, and the AhR-dependent transcription
Kabátková, Markéta, Svobodová, Jana, Pěnčíková, Kateřina, Mohatad, Dilshad Shaik, Šmerdová, Lenka, Kozubík, Alois, Machala, Miroslav, Vondráček, Jan
Published in Toxicology letters (05.01.2015)
Published in Toxicology letters (05.01.2015)
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Inflammatory mediators accelerate metabolism of benzo[ a ]pyrene in rat alveolar type II cells: The role of enhanced cytochrome P450 1B1 expression
Šmerdová, Lenka, Neča, Jiří, Svobodová, Jana, Topinka, Jan, Schmuczerová, Jana, Kozubík, Alois, Machala, Miroslav, Vondráček, Jan
Published in Toxicology (Amsterdam) (06.12.2013)
Published in Toxicology (Amsterdam) (06.12.2013)
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Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells
Lauková, Jarmila, Kozubík, Alois, Hofmanová, Jiřina, Nekvindová, Jana, Sova, Petr, Moyer, Mary Pat, Ehrmann, Jiří, Hyršlová Vaculová, Alena
Published in PloS one (22.10.2015)
Published in PloS one (22.10.2015)
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Differential effects of indirubin and 2,3,7,8-tetrachlorodibenzo- p -dioxin on the aryl hydrocarbon receptor (AhR) signalling in liver progenitor cells
Procházková, Jiřina, Kozubík, Alois, Machala, Miroslav, Vondráček, Jan
Published in Toxicology (Amsterdam) (11.01.2011)
Published in Toxicology (Amsterdam) (11.01.2011)
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Automatic cell cloning assay for determining the clonogenic capacity of cancer and cancer stem‐like cells
Fedr, Radek, Pernicová, Zuzana, Slabáková, Eva, Straková, Nicol, Bouchal, Jan, Grepl, Michal, Kozubík, Alois, Souček, Karel
Published in Cytometry. Part A (01.05.2013)
Published in Cytometry. Part A (01.05.2013)
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Deregulation of Cell Proliferation by Polycyclic Aromatic Hydrocarbons in Human Breast Carcinoma MCF-7 Cells Reflects Both Genotoxic and Nongenotoxic Events
Plíšková, Martina, Vondráček, Jan, Vojtěšek, Bořivoj, Kozubík, Alois, Machala, Miroslav
Published in Toxicological sciences (01.02.2005)
Published in Toxicological sciences (01.02.2005)
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Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells
Jendželovský, Rastislav, Mikeš, Jaromír, Koval’, Ján, Souček, Karel, Procházková, Jiřina, Kello, Martin, Sačková, Veronika, Hofmanová, Jiřina, Kozubík, Alois, Fedoročko, Peter
Published in Photochemical & photobiological sciences (01.12.2009)
Published in Photochemical & photobiological sciences (01.12.2009)
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Growth/differentiation factor-15 inhibits differentiation into osteoclasts—A novel factor involved in control of osteoclast differentiation
Vaňhara, Petr, Lincová, Eva, Kozubík, Alois, Jurdic, Pierre, Souček, Karel, Šmarda, Jan
Published in Differentiation (London) (01.11.2009)
Published in Differentiation (London) (01.11.2009)
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