Prefrontal Acetylcholine Release Controls Cue Detection on Multiple Timescales
Parikh, Vinay, Kozak, Rouba, Martinez, Vicente, Sarter, Martin
Published in Neuron (Cambridge, Mass.) (04.10.2007)
Published in Neuron (Cambridge, Mass.) (04.10.2007)
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Social brain, social dysfunction and social withdrawal
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Published in Neuroscience and biobehavioral reviews (01.02.2019)
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Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor
Gray, David L., Allen, John A., Mente, Scot, O’Connor, Rebecca E., DeMarco, George J., Efremov, Ivan, Tierney, Patrick, Volfson, Dmitri, Davoren, Jennifer, Guilmette, Edward, Salafia, Michelle, Kozak, Rouba, Ehlers, Michael D.
Published in Nature communications (14.02.2018)
Published in Nature communications (14.02.2018)
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Activation of D1 receptors affects human reactivity and flexibility to valued cues
Soutschek, Alexander, Kozak, Rouba, de Martinis, Nicholas, Howe, William, Burke, Christopher J, Fehr, Ernst, Jetter, Alexander, Tobler, Philippe N
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2020)
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2020)
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The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists
Yohn, Samantha E., Santerre, Jessica L., Nunes, Eric J., Kozak, Rouba, Podurgiel, Samantha J., Correa, Mercè, Salamone, John D.
Published in Pharmacology, biochemistry and behavior (01.08.2015)
Published in Pharmacology, biochemistry and behavior (01.08.2015)
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A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/D5 receptor partial agonist (PF-06412562) in patients with stable schizophrenia
Arce, Estibaliz, Balice-Gordon, Rita, Duvvuri, Sridhar, Naylor, Melissa, Xie, Zhiyong, Harel, Brian, Kozak, Rouba, Gray, David L, DeMartinis, Nicholas
Published in Journal of psychopharmacology (Oxford) (01.10.2019)
Published in Journal of psychopharmacology (Oxford) (01.10.2019)
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The Effects of a Novel Non-catechol Dopamine Partial Agonist on Working Memory in the Aged Rhesus Monkey
Moore, Tara L, Young, Damon A, Killiany, Ronald J, Fonseca, Kari R, Volfson, Dmitri, Gray, David L, Balice-Gordon, Rita, Kozak, Rouba
Published in Frontiers in aging neuroscience (26.11.2021)
Published in Frontiers in aging neuroscience (26.11.2021)
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Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation
Kozak, Rouba, Kiss, Tamás, Dlugolenski, Keith, Johnson, David E., Gorczyca, Roxanne R., Kuszpit, Kyle, Harvey, Brian D., Stolyar, Polina, Sukoff Rizzo, Stacey J., Hoffmann, William E., Volfson, Dmitri, Hajós, Mihaly, Davoren, Jennifer E., Abbott, Amanda L., Williams, Graham V., Castner, Stacy A., Gray, David L.
Published in Frontiers in pharmacology (07.07.2020)
Published in Frontiers in pharmacology (07.07.2020)
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Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson's Disease
Bezard, Erwan, Gray, David, Kozak, Rouba, Leoni, Matthew, Combs, Cari, Duvvuri, Sridhar
Published in CNS & neurological disorders drug targets (01.01.2024)
Published in CNS & neurological disorders drug targets (01.01.2024)
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Dopaminergic D1 receptor stimulation affects effort and risk preferences
Soutschek, Alexander, Gvozdanovic, Geraldine, Kozak, Rouba, Duvvuri, Sridhar, de Martinis, Nicholas, Harel, Brian, Gray, David L, Fehr, Ernst, Jetter, Alexander, Tobler, Philippe N
Published in Biological psychiatry (1969) (01.04.2020)
Published in Biological psychiatry (1969) (01.04.2020)
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A novel dopamine D1 receptor agonist excites delay-dependent working memory-related neuronal firing in primate dorsolateral prefrontal cortex
Wang, Min, Datta, Dibyadeep, Enwright, John, Galvin, Veronica, Yang, Sheng-Tao, Paspalas, Constantinos, Kozak, Rouba, Gray, David L., Lewis, David A., Arnsten, Amy F.T.
Published in Neuropharmacology (15.05.2019)
Published in Neuropharmacology (15.05.2019)
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Dopaminergic D 1 Receptor Stimulation Affects Effort and Risk Preferences
Soutschek, Alexander, Gvozdanovic, Geraldine, Kozak, Rouba, Duvvuri, Sridhar, de Martinis, Nicholas, Harel, Brian, Gray, David L, Fehr, Ernst, Jetter, Alexander, Tobler, Philippe N
Published in Biological psychiatry (1969) (01.04.2020)
Published in Biological psychiatry (1969) (01.04.2020)
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Meta‐analysis of amantadine efficacy for improving preclinical research reliability
Stanley, Philip, Pioli, Elsa Y., Kozak, Rouba, Popiolek, Michael, Bezard, Erwan
Published in Movement disorders (01.10.2018)
Published in Movement disorders (01.10.2018)
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Nicotinic receptor subtypes differentially modulate glutamate release in the dorsal medial striatum
Howe, William M., Young, Damon A., Bekheet, George, Kozak, Rouba
Published in Neurochemistry international (01.11.2016)
Published in Neurochemistry international (01.11.2016)
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Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization
Davoren, Jennifer E, Nason, Deane, Coe, Jotham, Dlugolenski, Keith, Helal, Christopher, Harris, Anthony R, LaChapelle, Erik, Liang, Sidney, Liu, Yue, O’Connor, Rebecca, Orozco, Christine C, Rai, Brajesh K, Salafia, Michelle, Samas, Brian, Xu, Wenjian, Kozak, Rouba, Gray, David
Published in Journal of medicinal chemistry (27.12.2018)
Published in Journal of medicinal chemistry (27.12.2018)
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Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor
Butler, Christopher R., Popiolek, Michael, McAllister, Laura A., LaChapelle, Erik A., Kramer, Melissa, Beck, Elizabeth M., Mente, Scot, Brodney, Michael A., Brown, Matthew, Gilbert, Adam, Helal, Chris, Ogilvie, Kevin, Starr, Jeremy, Uccello, Daniel, Grimwood, Sarah, Edgerton, Jeremy, Garst-Orozco, Jonathan, Kozak, Rouba, Lotarski, Susan, Rossi, Amie, Smith, Deborah, O’Connor, Rebecca, Lazzaro, John, Steppan, Claire, Steyn, Stefanus J.
Published in Journal of medicinal chemistry (11.07.2024)
Published in Journal of medicinal chemistry (11.07.2024)
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Journal Article
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M 4 Muscarinic Acetylcholine Receptor
Butler, Christopher R, Popiolek, Michael, McAllister, Laura A, LaChapelle, Erik A, Kramer, Melissa, Beck, Elizabeth M, Mente, Scot, Brodney, Michael A, Brown, Matthew, Gilbert, Adam, Helal, Chris, Ogilvie, Kevin, Starr, Jeremy, Uccello, Daniel, Grimwood, Sarah, Edgerton, Jeremy, Garst-Orozko, Jonathan, Kozak, Rouba, Lotarski, Susan, Rossi, Amie, Smith, Deborah, O'Connor, Rebecca, Lazzaro, John, Steppan, Claire, Steyn, Stefanus J
Published in Journal of medicinal chemistry (11.07.2024)
Published in Journal of medicinal chemistry (11.07.2024)
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