Search Results - "Kožíšek, Milan" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein

by Smola, Miroslav, Gutten, Ondrej, Dejmek, Milan, Kožíšek, Milan, Evangelidis, Thomas, Tehrani, Zahra Aliakbar, Novotná, Barbora, Nencka, Radim, Birkuš, Gabriel, Rulíšek, Lubomír, Boura, Evzen
Published in Angewandte Chemie International Edition (26.04.2021)

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Apollon: a deoxyribozyme that generates a yellow product

Apollon: a deoxyribozyme that generates a yellow product

by Volek, Martin, Kurfürst, Jaroslav, Kožíšek, Milan, Srb, Pavel, Veverka, Václav, Curtis, Edward A
Published in Nucleic acids research (27.08.2024)

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Protein–Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory

Protein–Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory

by Vavřina, Zdeněk, Gutten, Ondrej, Smola, Miroslav, Zavřel, Martin, Aliakbar Tehrani, Zahra, Charvát, Vilém, Kožíšek, Milan, Boura, Evzen, Birkuš, Gabriel, Rulíšek, Lubomír
Published in Biochemistry (Easton) (02.03.2021)

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Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase

Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase

by Gregor, Jiří, Radilová, Kateřina, Brynda, Jiří, Fanfrlík, Jindřich, Konvalinka, Jan, Kožíšek, Milan
Published in Molecules (Basel, Switzerland) (14.02.2021)

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Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors

Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors

by Zima, Václav, Radilová, Kateřina, Kožíšek, Milan, Albiñana, Carlos Berenguer, Karlukova, Elena, Brynda, Jiří, Fanfrlík, Jindřich, Flieger, Miroslav, Hodek, Jan, Weber, Jan, Majer, Pavel, Konvalinka, Jan, Machara, Aleš
Published in European journal of medicinal chemistry (15.12.2020)

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Specific Inhibitors of HIV Capsid Assembly Binding to the C‑Terminal Domain of the Capsid Protein: Evaluation of 2‑Arylquinazolines as Potential Antiviral Compounds

Specific Inhibitors of HIV Capsid Assembly Binding to the C‑Terminal Domain of the Capsid Protein: Evaluation of 2‑Arylquinazolines as Potential Antiviral Compounds

by Machara, Aleš, Lux, Vanda, Kožíšek, Milan, Grantz Šašková, Klára, Štěpánek, Ondřej, Kotora, Martin, Parkan, Kamil, Pávová, Marcela, Glass, Bärbel, Sehr, Peter, Lewis, Joe, Müller, Barbara, Kräusslich, Hans-Georg, Konvalinka, Jan
Published in Journal of medicinal chemistry (28.01.2016)

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Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease

Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease

by Began, Jakub, Cordier, Baptiste, Březinová, Jana, Delisle, Jordan, Hexnerová, Rozálie, Srb, Pavel, Rampírová, Petra, Kožíšek, Milan, Baudet, Mathieu, Couté, Yohann, Galinier, Anne, Veverka, Václav, Doan, Thierry, Strisovsky, Kvido
Published in The EMBO journal (18.05.2020)

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Urea and Guanidinium Induced Denaturation of a Trp-Cage Miniprotein

Urea and Guanidinium Induced Denaturation of a Trp-Cage Miniprotein

by Heyda, Jan, Kožíšek, Milan, Bednárova, Lucie, Thompson, Gary, Konvalinka, Jan, Vondrášek, Jiří, Jungwirth, Pavel
Published in The journal of physical chemistry. B (21.07.2011)

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Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors

Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors

by Reiberger, Robert, Radilová, Kateřina, Kráľ, Michal, Zima, Václav, Majer, Pavel, Brynda, Jiří, Dračínský, Martin, Konvalinka, Jan, Kožíšek, Milan, Machara, Aleš
Published in International journal of molecular sciences (20.07.2021)

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structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor

structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor

by Hejdánek, Jakub, Radilová, Kateřina, Pachl, Petr, Hodek, Jan, Machara, Aleš, Weber, Jan, Řezáčová, Pavlína, Konvalinka, Jan, Kožíšek, Milan
Published in Antiviral research (01.01.2021)

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Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction

Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction

by Radilová, Kateřina, Zima, Václav, Kráľ, Michal, Machara, Aleš, Majer, Pavel, Hodek, Jan, Weber, Jan, Brynda, Jiří, Strmeň, Timotej, Konvalinka, Jan, Kožíšek, Milan
Published in Antiviral research (01.12.2022)

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Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

by Sivá, Monika, Svoboda, Michal, Veverka, Václav, Trempe, Jean-François, Hofmann, Kay, Kožíšek, Milan, Hexnerová, Rozálie, Sedlák, František, Belza, Jan, Brynda, Jiří, Šácha, Pavel, Hubálek, Martin, Starková, Jana, Flaisigová, Iva, Konvalinka, Jan, Šašková, Klára Grantz
Published in Scientific reports (27.07.2016)

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Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza

Kinetic, thermodynamic and structural analysis of tamiphosphor binding to neuraminidase of H1N1 (2009) pandemic influenza

by Albiñana, Carlos Berenguer, Machara, Aleš, Řezáčová, Pavlína, Pachl, Petr, Konvalinka, Jan, Kožíšek, Milan
Published in European journal of medicinal chemistry (04.10.2016)

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Preorganization of the catalytic Zn2+-binding site in the HNH nuclease motif—A solution study

Preorganization of the catalytic Zn2+-binding site in the HNH nuclease motif—A solution study

by Németh, Eszter, Kožíšek, Milan, Schilli, Gabriella K., Gyurcsik, Béla
Published in Journal of inorganic biochemistry (01.10.2015)

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Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1

Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1

by Zima, Václav, Albiñana, Carlos Berenguer, Rojíková, Kateřina, Pokorná, Jana, Pachl, Petr, Řezáčová, Pavlína, Hudlicky, Jason, Navrátil, Václav, Majer, Pavel, Konvalinka, Jan, Kožíšek, Milan, Machara, Aleš
Published in Bioorganic & medicinal chemistry (01.07.2019)

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Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

by Pokorná, Jana, Pachl, Petr, Karlukova, Elena, Hejdánek, Jakub, Řezáčová, Pavlína, Machara, Aleš, Hudlický, Jason, Konvalinka, Jan, Kožíšek, Milan
Published in Viruses (21.06.2018)

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Functional and Structural Characterization of Novel Type of Linker Connecting Capsid and Nucleocapsid Protein Domains in Murine Leukemia Virus

Functional and Structural Characterization of Novel Type of Linker Connecting Capsid and Nucleocapsid Protein Domains in Murine Leukemia Virus

by Doležal, Michal, Hadravová, Romana, Kožíšek, Milan, Bednárová, Lucie, Langerová, Hana, Ruml, Tomáš, Rumlová, Michaela
Published in The Journal of biological chemistry (23.09.2016)

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Chasing shadows: What determines DTI metrics in gray matter regions? An in vitro and in vivo study

Chasing shadows: What determines DTI metrics in gray matter regions? An in vitro and in vivo study

by Rulseh, Aaron M., Keller, Jiří, Tintěra, Jaroslav, Kožíšek, Milan, Vymazal, Josef
Published in Journal of magnetic resonance imaging (01.11.2013)

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GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions

GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions

by Grantz Šašková, Klára, Kozíšek, Milan, Stray, Kirsten, de Jong, Dorien, Rezáová, Pavlína, Brynda, Jirí, van Maarseveen, Noortje M, Nijhuis, Monique, Cihlár, Tomáš, Konvalinka, Jan
Published in Journal of Virology (01.03.2014)

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Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N‐terminal mutations

Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N‐terminal mutations

by Németh, Eszter, Körtvélyesi, Tamás, Thulstrup, Peter W., Christensen, Hans E. M., Kožíšek, Milan, Nagata, Kyosuke, Czene, Anikó, Gyurcsik, Béla
Published in Protein science (01.08.2014)

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