The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation
Larkin, Emily, Hager, Christopher, Chandra, Jyotsna, Mukherjee, Pranab K, Retuerto, Mauricio, Salem, Iman, Long, Lisa, Isham, Nancy, Kovanda, Laura, Borroto-Esoda, Katyna, Wring, Steve, Angulo, David, Ghannoum, Mahmoud
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Get full text
Journal Article
Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies
Hamed, Kamal, Engelhardt, Marc, Kovanda, Laura L., Huang, Jin Ju, Yan, Jean, Aram, Jalal A.
Published in Scientific reports (25.04.2023)
Published in Scientific reports (25.04.2023)
Get full text
Journal Article
In Vitro Activity of Isavuconazole against Opportunistic Fungal Pathogens from Two Mycology Reference Laboratories
Pfaller, Michael A, Rhomberg, Paul R, Wiederhold, Nathan P, Gibas, Connie, Sanders, Carmita, Fan, Hongxin, Mele, James, Kovanda, Laura L, Castanheira, Mariana
Published in Antimicrobial agents and chemotherapy (01.10.2018)
Published in Antimicrobial agents and chemotherapy (01.10.2018)
Get full text
Journal Article
Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi
Desai, Amit V, Kovanda, Laura L, Hope, William W, Andes, David, Mouton, Johan W, Kowalski, Donna L, Townsend, Robert W, Mujais, Salim, Bonate, Peter L
Published in Antimicrobial agents and chemotherapy (01.12.2017)
Published in Antimicrobial agents and chemotherapy (01.12.2017)
Get full text
Journal Article
Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses
Thompson, George R., Rendon, Adrian, dos Santos, Rodrigo Ribeiro, Queiroz-Telles, Flavio, Ostrosky-Zeichner, Luis, Azie, Nkechi, Maher, Rochelle, Lee, Misun, Kovanda, Laura, Engelhardt, Marc, Vazquez, Jose A., Cornely, Oliver A., Perfect, John R.
Published in Clinical infectious diseases (01.08.2016)
Published in Clinical infectious diseases (01.08.2016)
Get full text
Journal Article
Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response
Kovanda, Laura L., Kolamunnage-Dona, Ruwanthi, Neely, Michael, Maertens, Johan, Lee, Misun, Hope, William W.
Published in Clinical infectious diseases (01.06.2017)
Published in Clinical infectious diseases (01.06.2017)
Get full text
Journal Article
Safety, tolerability and immunogenicity of a novel 24-valent pneumococcal vaccine in toddlers: A phase 1 randomized controlled trial
Borys, Dorota, Rupp, Richard, Smulders, Ronald, Chichili, Gurunadh R., Kovanda, Laura L., Santos, Vicki, Malinoski, Frank, Siber, George, Malley, Richard, Sebastian, Shite
Published in Vaccine (11.04.2024)
Published in Vaccine (11.04.2024)
Get full text
Journal Article
Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)
Kovanda, Laura L, Desai, Amit V, Lu, Qiaoyang, Townsend, Robert W, Akhtar, Shahzad, Bonate, Peter, Hope, William W
Published in Antimicrobial agents and chemotherapy (01.08.2016)
Published in Antimicrobial agents and chemotherapy (01.08.2016)
Get full text
Journal Article
Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis
Kovanda, Laura L, Sass, Gabriele, Martinez, Marife, Clemons, Karl V, Nazik, Hasan, Kitt, Therese M, Wiederhold, Nathan, Hope, William W, Stevens, David A
Published in Antimicrobial agents and chemotherapy (18.05.2021)
Published in Antimicrobial agents and chemotherapy (18.05.2021)
Get full text
Journal Article
Safety, Tolerability, and Population Pharmacokinetics of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients
Arrieta, Antonio C, Neely, Michael, Day, J Christopher, Rheingold, Susan R, Sue, Paul K, Muller, William J, Danziger-Isakov, Lara A, Chu, Julie, Yildirim, Inci, McComsey, Grace A, Frangoul, Haydar A, Chen, Tempe K, Statler, Victoria A, Steinbach, William J, Yin, Dwight E, Hamed, Kamal, Jones, Mark E, Lademacher, Christopher, Desai, Amit, Micklus, Kelley, Phillips, Desiree Leiva, Kovanda, Laura L, Walsh, Thomas J
Published in Antimicrobial agents and chemotherapy (16.07.2021)
Published in Antimicrobial agents and chemotherapy (16.07.2021)
Get full text
Journal Article
Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints
Kovanda, Laura L, Petraitiene, Ruta, Petraitis, Vidmantas, Walsh, Thomas J, Desai, Amit, Bonate, Peter, Hope, William W
Published in Journal of antimicrobial chemotherapy (01.07.2016)
Published in Journal of antimicrobial chemotherapy (01.07.2016)
Get full text
Journal Article
A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants With Invasive Candidiasis
Benjamin, Jr, Daniel K, Kaufman, David A, Hope, William W, Smith, P Brian, Arrieta, Antonio, Manzoni, Paolo, Kovanda, Laura L, Lademacher, Christopher, Isaacson, Brigit, Jednachowski, Deborah, Wu, Chunzhang, Kaibara, Atsunori, Walsh, Thomas J
Published in The Pediatric infectious disease journal (01.10.2018)
Published in The Pediatric infectious disease journal (01.10.2018)
Get more information
Journal Article
Population Pharmacokinetic Modeling of VL-2397, a Novel Systemic Antifungal Agent: Analysis of a Single- and Multiple-Ascending-Dose Study in Healthy Subjects
Kovanda, Laura L, Sullivan, Sean M, Smith, Larry R, Desai, Amit V, Bonate, Pete L, Hope, William W
Published in Antimicrobial agents and chemotherapy (01.06.2019)
Published in Antimicrobial agents and chemotherapy (01.06.2019)
Get full text
Journal Article
Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole
Kovanda, Laura L, Marty, Francisco M, Maertens, Johan, Desai, Amit V, Lademacher, Christopher, Engelhardt, Marc, Lu, Qiaoyang, Hope, William W
Published in Antimicrobial agents and chemotherapy (01.06.2017)
Published in Antimicrobial agents and chemotherapy (01.06.2017)
Get full text
Journal Article
Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis
Petraitis, Vidmantas, Petraitiene, Ruta, Moradi, Patriss W, Strauss, Gittel E, Katragkou, Aspasia, Kovanda, Laura L, Hope, William W, Walsh, Thomas J
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Get full text
Journal Article
Use of Pharmacokinetic-Pharmacodynamic Analyses To Optimize Therapy with the Systemic Antifungal Micafungin for Invasive Candidiasis or Candidemia
ANDES, David, AMBROSE, Paul G, HAMMEL, Jeffrey P, VAN WART, Scott A, IYER, Varsha, REYNOLDS, Daniel K, BUELL, Donald N, KOVANDA, Laura L, BHAVNANI, Sujata M
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Get full text
Journal Article
Outcomes by MIC Values for Patients Treated with Isavuconazole or Voriconazole for Invasive Aspergillosis in the Phase 3 SECURE and VITAL Trials
Andes, David R, Ghannoum, Mahmoud A, Mukherjee, Pranab K, Kovanda, Laura L, Lu, Qiaoyang, Jones, Mark E, Santerre Henriksen, Anne, Lademacher, Christopher, Hope, William W
Published in Antimicrobial agents and chemotherapy (01.01.2019)
Published in Antimicrobial agents and chemotherapy (01.01.2019)
Get full text
Journal Article
Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis
Kovanda, Laura L, Giamberardino, Charles, McEntee, Laura, Toffaletti, Dena L, Franke, Kelly S, Bartuska, Andrew, Smilnak, Gordon, de Castro, George C, Ripple, Katelyn, Hope, William W, Perfect, John R
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Get full text
Journal Article
Prognostic value of galactomannan: current evidence for monitoring response to antifungal therapy in patients with invasive aspergillosis
Kovanda, Laura L., Desai, Amit V., Hope, William W.
Published in Journal of Pharmacokinetics and Pharmacodynamics (01.04.2017)
Published in Journal of Pharmacokinetics and Pharmacodynamics (01.04.2017)
Get full text
Journal Article
Book Review
Clinical Pharmacodynamic Index Identification for Micafungin in Esophageal Candidiasis: Dosing Strategy Optimization
ANDES, David R, REYNOLDS, Daniel K, VAN WART, Scott A, LEPAK, Alexander J, KOVANDA, Laura L, BHAVNANI, Sujata M
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Get full text
Journal Article