Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation
Purohit, Anil, Rokita, Adam G, Guan, Xiaoqun, Chen, Biyi, Koval, Olha M, Voigt, Niels, Neef, Stefan, Sowa, Thomas, Gao, Zhan, Luczak, Elizabeth D, Stefansdottir, Hrafnhildur, Behunin, Andrew C, Li, Na, El-Accaoui, Ramzi N, Yang, Baoli, Swaminathan, Paari Dominic, Weiss, Robert M, Wehrens, Xander H.T, Song, Long-Sheng, Dobrev, Dobromir, Maier, Lars S, Anderson, Mark E
Published in Circulation (New York, N.Y.) (15.10.2013)
Published in Circulation (New York, N.Y.) (15.10.2013)
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CaMKII (Ca2+/Calmodulin-Dependent Kinase II) in Mitochondria of Smooth Muscle Cells Controls Mitochondrial Mobility, Migration, and Neointima Formation
Nguyen, Emily K, Koval, Olha M, Noble, Paige, Broadhurst, Kim, Allamargot, Chantal, Wu, Meng, Strack, Stefan, Thiel, William H, Grumbach, Isabella M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2018)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2018)
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The mitochondrial uniporter controls fight or flight heart rate increases
Wu, Yuejin, Rasmussen, Tyler P, Koval, Olha M, Joiner, Mei-Ling A, Hall, Duane D, Chen, Biyi, Luczak, Elizabeth D, Wang, Qiongling, Rokita, Adam G, Wehrens, Xander H T, Song, Long-Sheng, Anderson, Mark E
Published in Nature communications (20.01.2015)
Published in Nature communications (20.01.2015)
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Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
Rasmussen, Tyler P, Yuejin Wu, Mei-ling A. Joiner, Olha M. Koval, Nicholas R. Wilson, Elizabeth D. Luczak, Qinchuan Wang, Biyi Chen, Zhan Gao, Zhiyong Zhu, Brett A. Wagner, Jamie Soto, Michael L. McCormick, William Kutschke, Robert M. Weiss, Liping Yu, Ryan L. Boudreau, E. Dale Abel, Fenghuang Zhan, Douglas R. Spitz, Garry R. Buettner, Long-Sheng Song, Leonid V. Zingman, Mark E. Anderson
Published in Proceedings of the National Academy of Sciences - PNAS (21.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (21.07.2015)
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Journal Article
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
He, B Julie, Joiner, Mei-Ling A, Singh, Madhu V, Luczak, Elizabeth D, Swaminathan, Paari Dominic, Koval, Olha M, Kutschke, William, Allamargot, Chantal, Yang, Jinying, Guan, Xiaoqun, Zimmerman, Kathy, Grumbach, Isabella M, Weiss, Robert M, Spitz, Douglas R, Sigmund, Curt D, Blankesteijn, W Matthijs, Heymans, Stephane, Mohler, Peter J, Anderson, Mark E
Published in Nature medicine (01.12.2011)
Published in Nature medicine (01.12.2011)
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Regulation of Smooth Muscle Cell Proliferation by Mitochondrial Ca2+ in Type 2 Diabetes
Koval, Olha M, Nguyen, Emily K, Mittauer, Dylan J, Ait-Aissa, Karima, Chinchankar, William C, Grumbach, Isabella M
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
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Journal Article
Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity
Murthy, Shubha, Koval, Olha M, Ramiro Diaz, Juan M, Kumar, Santosh, Nuno, Daniel, Scott, Jason A, Allamargot, Chantal, Zhu, Linda J, Broadhurst, Kim, Santhana, Velarchana, Kutschke, William J, Irani, Kaikobad, Lamping, Kathryn G, Grumbach, Isabella M
Published in PloS one (23.10.2017)
Published in PloS one (23.10.2017)
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Short‐Term Statin Treatment Reduces, and Long‐Term Statin Treatment Abolishes, Chronic Vascular Injury by Radiation Therapy
Ait‐Aissa, Karima, Guo, Xutong, Klemmensen, Madelyn, Juhr, Denise, Leng, Linette N., Koval, Olha M., Grumbach, Isabella M.
Published in Journal of the American Heart Association (02.07.2024)
Published in Journal of the American Heart Association (02.07.2024)
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Journal Article
Ca2+/Calmodulin-Dependent Protein Kinase II―Based Regulation of Voltage-Gated Na+ Channel in Cardiac Disease
KOVAL, Olha M, SNYDER, Jedidiah S, LAN QIAN, MITCHELL, Colleen C, BOYDEN, Penelope A, BINKLEY, Philip F, CHENGLONG LI, ANDERSON, Mark E, MOHLER, Peter J, HUND, Thomas J, WOLF, Roseanne M, PAVLOVICZ, Ryan E, GLYNN, Patric, CURRAN, Jerry, LEYMASTER, Nicholas D, WEN DUN, WRIGHT, Patrick J, CARDONA, Natalia
Published in Circulation (New York, N.Y.) (23.10.2012)
Published in Circulation (New York, N.Y.) (23.10.2012)
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Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice
McLendon, Jared M., Zhang, Xiaoming, Matasic, Daniel S., Kumar, Mohit, Koval, Olha M., Grumbach, Isabella M., Sadayappan, Sakthivel, London, Barry, Boudreau, Ryan L.
Published in Journal of the American Heart Association (05.07.2022)
Published in Journal of the American Heart Association (05.07.2022)
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CaV1.2 β-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations
Koval, Olha M, Guan, Xiaoquan, Wu, Yuejin, Joiner, Mei-ling, Gao, Zhan, Chen, Biyi, Grumbach, Isabella M, Luczak, Elizabeth D, Colbran, Roger J, Song, Long-Sheng, Hund, Thomas J, Mohler, Peter J, Anderson, Mark E
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
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Journal Article
Calmodulin kinase II is required for fight or flight sinoatrial node physiology
Wu, Yuejin, Gao, Zhan, Chen, Biyi, Koval, Olha M, Singh, Madhu V, Guan, Xiaoqun, Hund, Thomas J, Kutschke, William, Sarma, Satyam, Grumbach, Isabella M, Wehrens, Xander H.T, Mohler, Peter J, Song, Long-Sheng, Anderson, Mark E
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
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Journal Article
Mechanisms by which statins protect endothelial cells from radiation-induced injury in the carotid artery
Ait-Aissa, Karima, Leng, Linette N, Lindsey, Nathanial R, Guo, Xutong, Juhr, Denise, Koval, Olha M, Grumbach, Isabella M
Published in Frontiers in cardiovascular medicine (19.06.2023)
Published in Frontiers in cardiovascular medicine (19.06.2023)
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Journal Article
Proarrhythmic Defects in Timothy Syndrome Require Calmodulin Kinase II
THIEL, William H, BIYI CHEN, HUND, Thomas J, KOVAL, Olha M, PUROHIT, Anil, SONG, Long-Sheng, MOHLER, Peter J, ANDERSON, Mark E
Published in Circulation (New York, N.Y.) (25.11.2008)
Published in Circulation (New York, N.Y.) (25.11.2008)
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Sex-Specific Differences in Endothelial Function Are Driven by Divergent Mitochondrial Ca2+ Handling
Damacena de Angelis, Celio, Endoni, Benney T, Nuno, Daniel, Lamping, Kathryn, Ledolter, Johannes, Koval, Olha M, Grumbach, Isabella M
Published in Journal of the American Heart Association (05.07.2022)
Published in Journal of the American Heart Association (05.07.2022)
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Journal Article
Genetic Inhibition of Na+-Ca2+ Exchanger Current Disables Fight or Flight Sinoatrial Node Activity Without Affecting Resting Heart Rate
Gao, Zhan, Rasmussen, Tyler P, Li, Yue, Kutschke, William, Koval, Olha M, Wu, Yiming, Wu, Yuejin, Hall, Duane D, Joiner, Mei-ling A, Wu, Xiang-Qiong, Swaminathan, Paari D, Purohit, Anil, Zimmerman, Kathy, Weiss, Robert M, Philipson, Kenneth D, Song, Long-sheng, Hund, Thomas J, Anderson, Mark E
Published in Circulation research (18.01.2013)
Published in Circulation research (18.01.2013)
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Journal Article
βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells
Kline, Crystal F., Wright, Patrick J., Koval, Olha M., Zmuda, Erik J., Johnson, Benjamin L., Anderson, Mark E., Hai, Tsonwin, Hund, Thomas J., Mohler, Peter J.
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (22.10.2013)
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Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription
Pennington, Steven M., Klutho, Paula R., Xie, Litao, Broadhurst, Kim, Koval, Olha M., McCormick, Michael L., Spitz, Douglas R., Grumbach, Isabella M.
Published in Redox biology (01.06.2018)
Published in Redox biology (01.06.2018)
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Dual role of KATP channel C-terminal motif in membrane targeting and metabolic regulation
Kline, Crystal F, Kurata, Harley T, Hund, Thomas J, Cunha, Shane R, Koval, Olha M, Wright, Patrick J, Christensen, Matthew, Anderson, Mark E, Nichols, Colin G, Mohler, Peter J
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2009)
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