Differences in activities and substrate specificity of human and murine pyrimidine nucleoside phosphorylases : implications for chemotherapy with 5-fluoropyrimidines
EL KOUNI, M. H, EL KOUNI, M. M, NAGUIB, F. N. M
Published in Cancer research (Chicago, Ill.) (15.08.1993)
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Published in Cancer research (Chicago, Ill.) (15.08.1993)
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Metabolism and Selective Toxicity of 6-Nitrobenzylthioinosine in Toxoplasma gondii
EL KOUNI, M. H, GUARCELLO, V, AL SAFARJALANI, O. N, NAGUIB, F. N. M
Published in Antimicrobial Agents and Chemotherapy (01.10.1999)
Published in Antimicrobial Agents and Chemotherapy (01.10.1999)
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Uridine phosphorylase inhibitors: Chemical modification of benzyloxybenzyl-barbituric acid and its effects on UrdPase inhibition
Guerin, David J., Mazeas, Daniel, Musale, Manoj S., Naguib, Fardos N.M., Al Safarjalani, Omar N., el Kouni, Mahmoud H., Panzica, Raymond P.
Published in Bioorganic & medicinal chemistry letters (07.06.1999)
Published in Bioorganic & medicinal chemistry letters (07.06.1999)
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Pyrimidine nucleobase ligands of orotate phosphoribosyltransferase from toxoplasma gondii
Javaid, Zahid Z, el Kouni, Mahmoud H, Iltzsch, Max H
Published in Biochemical pharmacology (01.11.1999)
Published in Biochemical pharmacology (01.11.1999)
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Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity
PLACIDI, L, CRETTON-SCOTT, E, GOSSELIN, G, PIERRA, C, SCHINAZI, R. F, IMBACH, J.-L, EL KOUNI, M. H, SOMMADOSSI, J.-P
Published in Antimicrobial Agents and Chemotherapy (01.04.2000)
Published in Antimicrobial Agents and Chemotherapy (01.04.2000)
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O.1.2 - EVALUATION OF PATIENT POSITIONING BETWEEN SURFACE-GUIDED RADIOTHERAPY AND THREE-POINT MARKERS
Psarras, M., Stasinou, D., Stroubinis, T., Zygogianni, A., Protopapa, M., Kouni, M., Kouloulias, V., Platoni, K.
Published in Physica medica (01.12.2022)
Published in Physica medica (01.12.2022)
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Journal Article
EVALUATION OF PATIENT POSITIONING BETWEEN SURFACE-GUIDED RADIOTHERAPY AND THREE-POINT MARKERS
Psarras, M., Stasinou, D., Stroubinis, T., Zygogianni, A., Protopapa, M., Kouni, M., Kouloulias, V., Platoni, K.
Published in Physica medica (01.12.2022)
Published in Physica medica (01.12.2022)
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Enzymes of uracil catabolism in normal and neoplastic human tissues
NAGUIB, F. N. M, EL KOUNI, M. H, SUNGMAN CHA
Published in Cancer research (Chicago, Ill.) (01.11.1985)
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Published in Cancer research (Chicago, Ill.) (01.11.1985)
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Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2′,3′,5′-tri- O-acetyluridine, a prodrug of uridine
Ashour, Osama M, Naguib, Fardos N.M, Panzica, Raymond P, Al Safarjalani, Omar N, el Kouni, Mahmoud H
Published in Biochemical pharmacology (01.08.2000)
Published in Biochemical pharmacology (01.08.2000)
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The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression
Chiang, C W, Carter, N, Sullivan, Jr, W J, Donald, R G, Roos, D S, Naguib, F N, el Kouni, M H, Ullman, B, Wilson, C M
Published in The Journal of biological chemistry (03.12.1999)
Published in The Journal of biological chemistry (03.12.1999)
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Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase : relevance to chemotherapy
ASHOUR, O. M, AL SAFARJALANI, O. N, NAGUIB, F. N. M, GOUDGAON, N. M, SCHINAZI, R. F, EL KOUNI, M. H
Published in Cancer chemotherapy and pharmacology (2000)
Published in Cancer chemotherapy and pharmacology (2000)
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Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii
el Kouni, Mahmoud H., Naguib, Fardos N.M., Panzica, Raymond P., Otter, Brian A., Chu, Shih-Hsi, Gosselin, Gilles, Chu, Chung K., Schinazi, Raymond F., Shealy, Y.Fulmer, Goudgaon, Naganna, Ozerov, Alexander A., Ueda, Tohru, Iltzsch, Max H.
Published in Biochemical pharmacology (28.06.1996)
Published in Biochemical pharmacology (28.06.1996)
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Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy
AL SAFARJALANI, Omar N, ZHOU, Xiao-Jian, NAGUIB, Fardos N. M, GOUDGAON, Naganna M, SCHINAZI, Raymond F, EL KOUNI, Mahmoud H
Published in Cancer chemotherapy and pharmacology (01.08.2001)
Published in Cancer chemotherapy and pharmacology (01.08.2001)
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Effect of administration of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on the anti-tumor efficacy of 5-fluoro-2′-deoxyuridine against murine colon tumor C26–10
Ashour, Osama M, Naguib, Fardos N.M, Goudgaon, Naganna M, Schinazi, Raymond F, el Kouni, Mahmoud H
Published in Biochemical pharmacology (01.09.2000)
Published in Biochemical pharmacology (01.09.2000)
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Journal Article
Effect of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on plasma concentration of uridine released from 2', 3', 5'-tri-O-acetyluridine, a prodrug of uridine: relevance to uridine rescue in chemotherapy
ASHOUR, O. M, NAGUIB, F. N. M, GOUDGAON, N. M, SCHINAZI, R. F, EL KOUNI, M. H
Published in Cancer chemotherapy and pharmacology (2000)
Published in Cancer chemotherapy and pharmacology (2000)
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Enhancement of 5-fluoro-2'-deoxyuridine antitumor efficacy by the uridine phosphorylase inhibitor 5-(benzyloxybenzyl)barbituric acid acyclonucleoside
ASHOUR, O. M, NAGUIB, F. N. M, KHALIFA, M. M. A, ABDEL-RAHEEM, M. H, PANZICA, R. P, EL KOUNI, M. H
Published in Cancer research (Chicago, Ill.) (01.03.1995)
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Published in Cancer research (Chicago, Ill.) (01.03.1995)
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Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyltransferase from Toxoplasma gondii
Naguib, Fardos N.M., Iltzsch, Max H., el Kouni, Mustapha M., Panzica, Raymond P., el Kouni, Mahmoud H.
Published in Biochemical pharmacology (01.01.1995)
Published in Biochemical pharmacology (01.01.1995)
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