Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
McCauley, Katherine B., Hawkins, Finn, Serra, Maria, Thomas, Dylan C., Jacob, Anjali, Kotton, Darrell N.
Published in Cell stem cell (01.06.2017)
Published in Cell stem cell (01.06.2017)
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Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration
Alysandratos, Konstantinos-Dionysios, Herriges, Michael J, Kotton, Darrell N
Published in Annual review of physiology (10.02.2021)
Published in Annual review of physiology (10.02.2021)
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Next-Generation Regeneration: The Hope and Hype of Lung Stem Cell Research
KOTTON, Darrell N
Published in American journal of respiratory and critical care medicine (15.06.2012)
Published in American journal of respiratory and critical care medicine (15.06.2012)
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Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells
Jacob, Anjali, Vedaie, Marall, Roberts, David A., Thomas, Dylan C., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Hawkins, Finn, Kotton, Darrell N.
Published in Nature protocols (01.12.2019)
Published in Nature protocols (01.12.2019)
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Regeneration and orthotopic transplantation of a bioartificial lung
Ott, Harald C, Clippinger, Ben, Conrad, Claudius, Schuetz, Christian, Pomerantseva, Irina, Ikonomou, Laertis, Kotton, Darrell, Vacanti, Joseph P
Published in Nature medicine (01.08.2010)
Published in Nature medicine (01.08.2010)
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SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response
Huang, Jessie, Hume, Adam J., Abo, Kristine M., Werder, Rhiannon B., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Beermann, Mary Lou, Simone-Roach, Chantelle, Lindstrom-Vautrin, Jonathan, Olejnik, Judith, Suder, Ellen L., Bullitt, Esther, Hinds, Anne, Sharma, Arjun, Bosmann, Markus, Wang, Ruobing, Hawkins, Finn, Burks, Eric J., Saeed, Mohsan, Wilson, Andrew A., Mühlberger, Elke, Kotton, Darrell N.
Published in Cell Stem Cell (03.12.2020)
Published in Cell Stem Cell (03.12.2020)
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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future
Basil, Maria C, Katzen, Jeremy, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J, Chapman, Hal A, Kotton, Darrell N, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Morrisey, Edward E
Published in Cell stem cell (02.04.2020)
Published in Cell stem cell (02.04.2020)
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SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes
Li, Yize, Renner, David M., Comar, Courtney E., Whelan, Jillian N., Reyes, Hanako M., Cardenas-Diaz, Fabian Leonardo, Truitt, Rachel, Tan, Li Hui, Dong, Beihua, Alysandratos, Konstantinos Dionysios, Huang, Jessie, Palmer, James N., Adappa, Nithin D., Kohanski, Michael A., Kotton, Darrell N., Silverman, Robert H., Yang, Wenli, Morrisey, Edward E., Cohen, Noam A., Weiss, Susan R.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2021)
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Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells
Kurmann, Anita A., Serra, Maria, Hawkins, Finn, Rankin, Scott A., Mori, Munemasa, Astapova, Inna, Ullas, Soumya, Lin, Sui, Bilodeau, Melanie, Rossant, Janet, Jean, Jyh C., Ikonomou, Laertis, Deterding, Robin R., Shannon, John M., Zorn, Aaron M., Hollenberg, Anthony N., Kotton, Darrell N.
Published in Cell stem cell (05.11.2015)
Published in Cell stem cell (05.11.2015)
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Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells
Longmire, Tyler A., Ikonomou, Laertis, Hawkins, Finn, Christodoulou, Constantina, Cao, Yuxia, Jean, J.C., Kwok, Letty W., Mou, Hongmei, Rajagopal, Jayaraj, Shen, Steven S., Dowton, Anne A., Serra, Maria, Weiss, Daniel J., Green, Michael D., Snoeck, Hans-Willem, Ramirez, Maria I., Kotton, Darrell N.
Published in Cell stem cell (06.04.2012)
Published in Cell stem cell (06.04.2012)
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Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells
Kathiriya, Jaymin J., Wang, Chaoqun, Zhou, Minqi, Brumwell, Alexis, Cassandras, Monica, Le Saux, Claude Jourdan, Cohen, Max, Alysandratos, Kostantinos-Dionysios, Wang, Bruce, Wolters, Paul, Matthay, Michael, Kotton, Darrell N., Chapman, Harold A., Peng, Tien
Published in Nature cell biology (01.01.2022)
Published in Nature cell biology (01.01.2022)
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Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19
Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Pretto, Carla D., Qiao, Yuanyuan, Zhang, Yuping, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Chinnaiyan, Arul M., Sexton, Jonathan Z.
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2021)
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Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells
Mithal, Aditya, Capilla, Amalia, Heinze, Dar, Berical, Andrew, Villacorta-Martin, Carlos, Vedaie, Marall, Jacob, Anjali, Abo, Kristine, Szymaniak, Aleksander, Peasley, Megan, Stuffer, Alexander, Mahoney, John, Kotton, Darrell N., Hawkins, Finn, Mostoslavsky, Gustavo
Published in Nature communications (10.01.2020)
Published in Nature communications (10.01.2020)
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Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
Hawkins, Finn J., Suzuki, Shingo, Beermann, Mary Lou, Barillà, Cristina, Wang, Ruobing, Villacorta-Martin, Carlos, Berical, Andrew, Jean, J.C., Le Suer, Jake, Matte, Taylor, Simone-Roach, Chantelle, Tang, Yang, Schlaeger, Thorsten M., Crane, Ana M., Matthias, Nadine, Huang, Sarah X.L., Randell, Scott H., Wu, Joshua, Spence, Jason R., Carraro, Gianni, Stripp, Barry R., Rab, Andras, Sorsher, Eric J., Horani, Amjad, Brody, Steven L., Davis, Brian R., Kotton, Darrell N.
Published in Cell stem cell (07.01.2021)
Published in Cell stem cell (07.01.2021)
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Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells
Jacob, Anjali, Morley, Michael, Hawkins, Finn, McCauley, Katherine B., Jean, J.C., Heins, Hillary, Na, Cheng-Lun, Weaver, Timothy E., Vedaie, Marall, Hurley, Killian, Hinds, Anne, Russo, Scott J., Kook, Seunghyi, Zacharias, William, Ochs, Matthias, Traber, Katrina, Quinton, Lee J., Crane, Ana, Davis, Brian R., White, Frances V., Wambach, Jennifer, Whitsett, Jeffrey A., Cole, F. Sessions, Morrisey, Edward E., Guttentag, Susan H., Beers, Michael F., Kotton, Darrell N.
Published in Cell stem cell (05.10.2017)
Published in Cell stem cell (05.10.2017)
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scTOP: physics-inspired order parameters for cellular identification and visualization
Yampolskaya, Maria, Herriges, Michael J, Ikonomou, Laertis, Kotton, Darrell N, Mehta, Pankaj
Published in Development (Cambridge) (01.11.2023)
Published in Development (Cambridge) (01.11.2023)
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