Development of Novel Potent Orally Bioavailable Oseltamivir Derivatives Active against Resistant Influenza A
Schade, Dennis, Kotthaus, Joscha, Riebling, Lukas, Kotthaus, Jürke, Müller-Fielitz, Helge, Raasch, Walter, Koch, Oliver, Seidel, Nora, Schmidtke, Michaela, Clement, Bernd
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
Get full text
Journal Article
Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC)
Kotthaus, Jürke, Wahl, Bettina, Havemeyer, Antje, Kotthaus, Joscha, Schade, Dennis, Garbe-Schönberg, Dieter, Mendel, Ralf, Bittner, Florian, Clement, Bernd
Published in Biochemical journal (15.01.2011)
Published in Biochemical journal (15.01.2011)
Get more information
Journal Article
The Fourth Molybdenum Containing Enzyme mARC: Cloning and Involvement in the Activation of N-Hydroxylated Prodrugs
Gruenewald, Sanja, Wahl, Bettina, Bittner, Florian, Hungeling, Helen, Kanzow, Stephanie, Kotthaus, Joscha, Schwering, Ulrike, Mendel, Ralf R, Clement, Bernd
Published in Journal of medicinal chemistry (25.12.2008)
Published in Journal of medicinal chemistry (25.12.2008)
Get full text
Journal Article
Synthesis and physicochemical characterization of novel 6-aminopyrido[3,4-c][1,9]phenanthrolines as aza-analogs of benzo[c]phenanthridines
Meier, Christopher, Kotthaus, Joscha, Stenzel, Lars, Girreser, Ulrich, Heber, Dieter, Clement, Bernd
Published in Tetrahedron (04.11.2012)
Published in Tetrahedron (04.11.2012)
Get full text
Journal Article
Prodrug design for the potent cardiovascular agent N-omega-hydroxy-L-arginine (NOHA): Synthetic approaches and physicochemical characterization
Schade, Dennis, Kotthaus, Juerke, Klein, Nikola, Kotthaus, Joscha, Clement, Bernd
Published in Organic & biomolecular chemistry (21.07.2011)
Published in Organic & biomolecular chemistry (21.07.2011)
Get full text
Journal Article
Analysis of highly potent amidine containing inhibitors of serine proteases and their N-hydroxylated prodrugs (amidoximes)
Kotthaus, Joscha, Steinmetzer, Torsten, van de Locht, Andreas, Clement, Bernd
Published in Journal of enzyme inhibition and medicinal chemistry (01.02.2011)
Published in Journal of enzyme inhibition and medicinal chemistry (01.02.2011)
Get full text
Journal Article
New 1 H ‐Pyrazole‐4‐Carboxamides with Antiplatelet Activity
Rehse, Klaus, Kotthaus, Joscha, Khadembashi, Laleh
Published in Archiv der Pharmazie (Weinheim) (01.01.2009)
Published in Archiv der Pharmazie (Weinheim) (01.01.2009)
Get full text
Journal Article
New 1H-Pyrazole-4-Carboxamides with Antiplatelet Activity
Rehse, Klaus, Kotthaus, Joscha, Khadembashi, Laleh
Published in Archiv der Pharmazie (Weinheim) (01.01.2009)
Published in Archiv der Pharmazie (Weinheim) (01.01.2009)
Get full text
Journal Article
Synthesis and biological evaluation of l-valine-amidoximeesters as double prodrugs of amidines
Kotthaus, Joscha, Hungeling, Helen, Reeh, Christiane, Kotthaus, Jürke, Schade, Dennis, Wein, Silvia, Wolffram, Siegfried, Clement, Bernd
Published in Bioorganic & medicinal chemistry (15.03.2011)
Published in Bioorganic & medicinal chemistry (15.03.2011)
Get full text
Journal Article
New Prodrugs of the Antiprotozoal Drug Pentamidine
Kotthaus, Joscha, Kotthaus, Jürke, Schade, Dennis, Schwering, Ulrike, Hungeling, Helen, Müller-Fielitz, Helge, Raasch, Walter, Clement, Bernd
Published in ChemMedChem (09.12.2011)
Published in ChemMedChem (09.12.2011)
Get full text
Journal Article
MS3 fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM3
Lakowski, Ted M., Szeitz, András, Pak, Magnolia L., Thomas, Dylan, Vhuiyan, Mynol I., Kotthaus, Joscha, Clement, Bernd, Frankel, Adam
Published in Journal of proteomics (27.03.2013)
Published in Journal of proteomics (27.03.2013)
Get full text
Journal Article
Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability
Schade, Dennis, Kotthaus, Jürke, Riebling, Lukas, Kotthaus, Joscha, Müller-Fielitz, Helge, Raasch, Walter, Hoffmann, Anja, Schmidtke, Michaela, Clement, Bernd
Published in Journal of pharmaceutical sciences (01.09.2015)
Published in Journal of pharmaceutical sciences (01.09.2015)
Get full text
Journal Article
Incorporation of neutral C-terminal residues in 3-amidinophenylalanine-derived matriptase inhibitors
Schweinitz, Andrea, Dönnecke, Daniel, Ludwig, Alexander, Steinmetzer, Peter, Schulze, Alexander, Kotthaus, Joscha, Wein, Silvia, Clement, Bernd, Steinmetzer, Torsten
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Get full text
Journal Article
Highly Potent and Selective Substrate Analogue Factor Xa Inhibitors Containing D-Homophenylalanine Analogues as P3 Residue: Part 2
Stürzebecher, Anne, Dönnecke, Daniel, Schweinitz, Andrea, Schuster, Oliver, Steinmetzer, Peter, Stürzebecher, Uta, Kotthaus, Joscha, Clement, Bernd, Stürzebecher, Jörg, Steinmetzer, Torsten
Published in ChemMedChem (09.07.2007)
Published in ChemMedChem (09.07.2007)
Get full text
Journal Article
MS³ fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM
Lakowski, Ted M, Szeitz, András, Pak, Magnolia L, Thomas, Dylan, Vhuiyan, Mynol I, Kotthaus, Joscha, Clement, Bernd, Frankel, Adam
Published in Journal of proteomics (27.03.2013)
Published in Journal of proteomics (27.03.2013)
Get more information
Journal Article