Biochemical and mechanical regulation of actin dynamics
Lappalainen, Pekka, Kotila, Tommi, Jégou, Antoine, Romet-Lemonne, Guillaume
Published in Nature reviews. Molecular cell biology (01.12.2022)
Published in Nature reviews. Molecular cell biology (01.12.2022)
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Journal Article
Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin
Kotila, Tommi, Wioland, Hugo, Enkavi, Giray, Kogan, Konstantin, Vattulainen, Ilpo, Jégou, Antoine, Romet-Lemonne, Guillaume, Lappalainen, Pekka
Published in Nature communications (22.11.2019)
Published in Nature communications (22.11.2019)
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Journal Article
Structural basis of actin monomer re-charging by cyclase-associated protein
Kotila, Tommi, Kogan, Konstantin, Enkavi, Giray, Guo, Siyang, Vattulainen, Ilpo, Goode, Bruce L, Lappalainen, Pekka
Published in Nature communications (14.05.2018)
Published in Nature communications (14.05.2018)
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Journal Article
Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro
Gateva, Gergana, Kremneva, Elena, Reindl, Theresia, Kotila, Tommi, Kogan, Konstantin, Gressin, Laurène, Gunning, Peter W., Manstein, Dietmar J., Michelot, Alphée, Lappalainen, Pekka
Published in Current biology (06.03.2017)
Published in Current biology (06.03.2017)
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Journal Article
A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
Colombo, Jessica, Antkowiak, Adrien, Kogan, Konstantin, Kotila, Tommi, Elliott, Jenna, Guillotin, Audrey, Lappalainen, Pekka, Michelot, Alphée
Published in Nature communications (22.01.2021)
Published in Nature communications (22.01.2021)
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Journal Article
UNC-45a promotes myosin folding and stress fiber assembly
Lehtimäki, Jaakko I, Fenix, Aidan M, Kotila, Tommi M, Balistreri, Giuseppe, Paavolainen, Lassi, Varjosalo, Markku, Burnette, Dylan T, Lappalainen, Pekka
Published in The Journal of cell biology (04.12.2017)
Published in The Journal of cell biology (04.12.2017)
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Journal Article
Regulation of INF2-mediated actin polymerization through site-specific lysine acetylation of actin itself
A, Mu, Fung, Tak Shun, Francomacaro, Lisa M., Huynh, Thao, Kotila, Tommi, Svindrych, Zdenek, Higgs, Henry N.
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
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Journal Article
Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite
Kotila, Tommi, Wioland, Hugo, Selvaraj, Muniyandi, Kogan, Konstantin, Antenucci, Lina, Jégou, Antoine, Huiskonen, Juha T, Romet-Lemonne, Guillaume, Lappalainen, Pekka
Published in Nature communications (15.06.2022)
Published in Nature communications (15.06.2022)
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Journal Article
Publisher Correction: Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks
Hakala, Markku, Wioland, Hugo, Tolonen, Mari, Kotila, Tommi, Jegou, Antoine, Romet-Lemonne, Guillaume, Lappalainen, Pekka
Published in Nature cell biology (01.04.2021)
Published in Nature cell biology (01.04.2021)
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Journal Article
Mechanism of Borrelia immune evasion by FhbA-related proteins
Kogan, Konstantin, Haapasalo, Karita, Kotila, Tommi, Moore, Robin, Lappalainen, Pekka, Goldman, Adrian, Meri, Taru
Published in PLoS pathogens (01.03.2022)
Published in PLoS pathogens (01.03.2022)
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Journal Article
Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi
Kolodziejczyk, Robert, Mikula, Kornelia M, Kotila, Tommi, Postis, Vincent L G, Jokiranta, T Sakari, Goldman, Adrian, Meri, Taru
Published in PloS one (30.11.2017)
Published in PloS one (30.11.2017)
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Journal Article
Leishmania profilin interacts with actin through an unusual structural mechanism to control cytoskeletal dynamics in parasites
Vizcaíno-Castillo, Andrea, Kotila, Tommi, Kogan, Konstantin, Yanase, Ryuji, Como, Juna, Antenucci, Lina, Michelot, Alphee, Sunter, Jack D., Lappalainen, Pekka
Published in The Journal of biological chemistry (01.03.2024)
Published in The Journal of biological chemistry (01.03.2024)
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Journal Article
Structural and biochemical basis of rapid actin dynamics in Leishmania parasites
Kotila, Tommi, Wioland, Hugo, Muniyandi, Selvaraj, Kogan, Konstantin, Antenucci, Lina, Jegou, Antoine G., Huiskonen, Juha, Romet-Lemonne, Guillaume, Lappalainen, Pekka
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Recycling of the actin monomer pool limits the lifetime of network turnover
Colin, Alexandra, Kotila, Tommi, Guérin, Christophe, Orhant‐Prioux, Magali, Vianay, Benoit, Mogilner, Alex, Lappalainen, Pekka, Théry, Manuel, Blanchoin, Laurent
Published in The EMBO journal (02.05.2023)
Published in The EMBO journal (02.05.2023)
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Journal Article
Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms
Selvaraj, Muniyandi, Kokate, Shrikant B., Reggiano, Gabriella, Kogan, Konstantin, Kotila, Tommi, Kremneva, Elena, DiMaio, Frank, Lappalainen, Pekka, Huiskonen, Juha T.
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
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Journal Article
Unusual actin-binding mechanism and the role of profilin in actin dynamics of trypanosomatid parasites
Vizcaíno-Castillo, Andrea, Kotila, Tommi, Kogan, Konstantin, Yanase, Ryuji, Como, Juna, Antenucci, Lina, Michelot, Alphee, Sunter, Jack D, Lappalainen, Pekka
Published in bioRxiv (06.01.2023)
Published in bioRxiv (06.01.2023)
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