Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease
Egan, Michael F, Kost, James, Tariot, Pierre N, Aisen, Paul S, Cummings, Jeffrey L, Vellas, Bruno, Sur, Cyrille, Mukai, Yuki, Voss, Tiffini, Furtek, Christine, Mahoney, Erin, Harper Mozley, Lyn, Vandenberghe, Rik, Mo, Yi, Michelson, David
Published in The New England journal of medicine (03.05.2018)
Published in The New England journal of medicine (03.05.2018)
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Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease
Egan, Michael F, Kost, James, Voss, Tiffini, Mukai, Yuki, Aisen, Paul S, Cummings, Jeffrey L, Tariot, Pierre N, Vellas, Bruno, van Dyck, Christopher H, Boada, Merce, Zhang, Ying, Li, Wen, Furtek, Christine, Mahoney, Erin, Harper Mozley, Lyn, Mo, Yi, Sur, Cyrille, Michelson, David
Published in The New England journal of medicine (11.04.2019)
Published in The New England journal of medicine (11.04.2019)
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Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial
Ho, Tony W, Dr, Ferrari, Michel D, Prof, Dodick, David W, Prof, Galet, Vince, PhD, Kost, James, PhD, Fan, Xiaoyin, PhD, Leibensperger, Heather, BS, Froman, Samar, BS, Assaid, Christopher, PhD, Lines, Christopher, PhD, Koppen, Hille, MD, Winner, Paul K, DO
Published in The Lancet (British edition) (20.12.2008)
Published in The Lancet (British edition) (20.12.2008)
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Further analyses of the safety of verubecestat in the phase 3 EPOCH trial of mild-to-moderate Alzheimer's disease
Egan, Michael F, Mukai, Yuki, Voss, Tiffini, Kost, James, Stone, Julie, Furtek, Christine, Mahoney, Erin, Cummings, Jeffrey L, Tariot, Pierre N, Aisen, Paul S, Vellas, Bruno, Lines, Christopher, Michelson, David
Published in Alzheimer's research & therapy (07.08.2019)
Published in Alzheimer's research & therapy (07.08.2019)
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Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study
Myers, Gary J, Davidson, Philip W, Cox, Christopher, Shamlaye, Conrad F, Palumbo, Donna, Cernichiari, Elsa, Sloane-Reeves, Jean, Wilding, Gregory E, Kost, James, Huang, Li-Shan, Clarkson, Thomas W
Published in The Lancet (British edition) (17.05.2003)
Published in The Lancet (British edition) (17.05.2003)
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Minimal Pharmacokinetic Interaction between the Human Immunodeficiency Virus Nonnucleoside Reverse Transcriptase Inhibitor Etravirine and the Integrase Inhibitor Raltegravir in Healthy Subjects
ANDERSON, Matt S, KAKUDA, Thomas N, IWAMOTO, Marian, HANLEY, William, MILLER, Jutta, KOST, James T, STOLTZ, Randall, WENNING, Larissa A, STONE, Julie A, HOETELMANS, Richard M. W, WAGNER, John A
Published in Antimicrobial Agents and Chemotherapy (01.12.2008)
Published in Antimicrobial Agents and Chemotherapy (01.12.2008)
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Randomized, controlled trial of telcagepant over four migraine attacks
Ho, Andrew P, Dahlöf, Carl GH, Silberstein, Stephen D, Saper, Joel R, Ashina, Messoud, Kost, James T, Froman, Samar, Leibensperger, Heather, Lines, Christopher R, Ho, Tony W
Published in Cephalalgia (01.12.2010)
Published in Cephalalgia (01.12.2010)
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Journal Article
Lack of a Significant Drug Interaction between Raltegravir and Tenofovir
WENNING, Larissa A, FRIEDMAN, Evan J, STONE, Julie A, IWAMOTO, Marian, KOST, James T, BREIDINGER, Sheila A, STEK, Jon E, LASSETER, Kenneth C, GOTTESDIENER, Keith M, CHEN, Joshua, TEPPLER, Hedy, WAGNER, John A
Published in Antimicrobial Agents and Chemotherapy (01.09.2008)
Published in Antimicrobial Agents and Chemotherapy (01.09.2008)
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Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir
IWAMOTO, Marian, WENNING, Larissa A, HAAZEN, Wouter, STONE, Julie A, GOTTESDIENER, Keith M, WAGNER, John A, PETRY, Amelia S, LAETHEM, Martine, DE SMET, Marina, KOST, James T, BREIDINGER, Sheila A, MANGIN, Eric C, AZROLAN, Neal, GREENBERG, Howard E
Published in Antimicrobial Agents and Chemotherapy (01.12.2008)
Published in Antimicrobial Agents and Chemotherapy (01.12.2008)
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Effect of Tipranavir-Ritonavir on Pharmacokinetics of Raltegravir
HANLEY, William D, WENNING, Larissa A, MOREAU, Allison, KOST, James T, MANGIN, Eric, SHAMP, Trisha, STONE, Julie A, GOTTESDIENER, Keith M, WAGNER, John A, IWAMOTO, Marian
Published in Antimicrobial Agents and Chemotherapy (01.07.2009)
Published in Antimicrobial Agents and Chemotherapy (01.07.2009)
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Journal Article
Lack of a Clinically Important Effect of Moderate Hepatic Insufficiency and Severe Renal Insufficiency on Raltegravir Pharmacokinetics
IWAMOTO, Marian, HANLEY, William D, STONE, Julie A, WAGNER, John A, PETRY, Amelia S, FRIEDMAN, Evan J, KOST, James T, BREIDINGER, Sheila A, LASSETER, Kenneth C, ROBSON, Richard, LUNDE, Norman M, WENNING, Larissa A
Published in Antimicrobial Agents and Chemotherapy (01.05.2009)
Published in Antimicrobial Agents and Chemotherapy (01.05.2009)
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Effect of raltegravir on estradiol and norgestimate plasma pharmacokinetics following oral contraceptive administration in healthy women
Anderson, Matt S., Hanley, William D., Moreau, Allison R., Jin, Bo, Bieberdorf, Frederick A., Kost, James T., Wenning, Larissa A., Stone, Julie A., Wagner, John A., Iwamoto, Marian
Published in British journal of clinical pharmacology (01.04.2011)
Published in British journal of clinical pharmacology (01.04.2011)
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Sexually Dimorphic Behavioral Responses to Prenatal Dioxin Exposure
Hojo, Rieko, Stern, Sander, Zareba, Grazyna, Markowski, Vincent P., Cox, Christopher, Kost, James T., Weiss, Bernard
Published in Environmental health perspectives (01.03.2002)
Published in Environmental health perspectives (01.03.2002)
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Testing Equality of Means Under Order Restrictions Using Multiple Contrasts
Kost, James T., McDermott, Michael P.
Published in Communications in statistics. Theory and methods (24.09.2008)
Published in Communications in statistics. Theory and methods (24.09.2008)
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BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain
Sur, Cyrille, Kost, James, Scott, David, Adamczuk, Katarzyna, Fox, Nick C, Cummings, Jeffrey L, Tariot, Pierre N, Aisen, Paul S, Vellas, Bruno, Voss, Tiffini, Mahoney, Erin, Mukai, Yuki, Kennedy, Matthew E, Lines, Christopher, Michelson, David, Egan, Michael F
Published in Brain (London, England : 1878) (01.12.2020)
Published in Brain (London, England : 1878) (01.12.2020)
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Progression from Prodromal Alzheimer’s Disease to Mild Alzheimer’s Disease Dementia in the Verubecestat APECS Study: Adjudicating Diagnostic Transitions
Voss, Tiffini, Kost, James, Mercer, Swati Pal, Furtek, Christine, Randolph, Christopher, Lines, Christopher, Egan, Michael F., Cummings, Jeffrey L.
Published in Journal of Alzheimer's disease (01.01.2023)
Published in Journal of Alzheimer's disease (01.01.2023)
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Journal Article
Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease
Wessels, Alette M., Lines, Christopher, Stern, Robert A., Kost, James, Voss, Tiffini, Mozley, Lyn Harper, Furtek, Christine, Mukai, Yuki, Aisen, Paul S., Cummings, Jeffrey L., Tariot, Pierre N., Vellas, Bruno, Dupre, Nicole, Randolph, Christopher, Michelson, David, Andersen, Scott W., Shering, Craig, Sims, John R., Egan, Michael F.
Published in Alzheimer's & dementia (01.11.2020)
Published in Alzheimer's & dementia (01.11.2020)
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Journal Article
Retinal Optical Coherence Tomography Metrics Are Unchanged in Verubecestat Alzheimer's Disease Clinical Trial but Correlate with Baseline Regional Brain Atrophy
Sergott, Robert C, Raji, Annaswamy, Kost, James, Sur, Cyrille, Jackson, Saheeda, Locco, Amy, Patel, Arpankumar, Furtek, Christine, Mattson, Britta, Egan, Michael F
Published in Journal of Alzheimer's disease (01.01.2021)
Published in Journal of Alzheimer's disease (01.01.2021)
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Evaluation of 18F-flutemetamol amyloid PET image analysis parameters on the effect of verubecestat on brain amlyoid load in Alzheimer’s disease
Sur, Cyrille, Adamczuk, Katarzyna, Scott, David, Kost, James, Sampat, Mehul, Buckley, Christopher, Farrar, Gill, Newton, Ben, Suhy, Joyce, Bennacef, Idriss, Egan, Michael F.
Published in Molecular imaging and biology (01.12.2022)
Published in Molecular imaging and biology (01.12.2022)
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