Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression
Fursova, Nadezda A., Blackledge, Neil P., Nakayama, Manabu, Ito, Shinsuke, Koseki, Yoko, Farcas, Anca M., King, Hamish W., Koseki, Haruhiko, Klose, Robert J.
Published in Molecular cell (06.06.2019)
Published in Molecular cell (06.06.2019)
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PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation
Almeida, Mafalda, Pintacuda, Greta, Masui, Osamu, Koseki, Yoko, Gdula, Michal, Cerase, Andrea, Brown, David, Mould, Arne, Innocent, Cassandravictoria, Nakayama, Manabu, Schermelleh, Lothar, Nesterova, Tatyana B., Koseki, Haruhiko, Brockdorff, Neil
Published in Science (American Association for the Advancement of Science) (09.06.2017)
Published in Science (American Association for the Advancement of Science) (09.06.2017)
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Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes
Sugishita, Hiroki, Kondo, Takashi, Ito, Shinsuke, Nakayama, Manabu, Yakushiji-Kaminatsui, Nayuta, Kawakami, Eiryo, Koseki, Yoko, Ohinata, Yasuhide, Sharif, Jafar, Harachi, Mio, Blackledge, Neil P., Klose, Robert J., Koseki, Haruhiko
Published in Nature communications (09.09.2021)
Published in Nature communications (09.09.2021)
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A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
Conway, Eric, Jerman, Emilia, Healy, Evan, Ito, Shinsuke, Holoch, Daniel, Oliviero, Giorgio, Deevy, Orla, Glancy, Eleanor, Fitzpatrick, Darren J., Mucha, Marlena, Watson, Ariane, Rice, Alan M., Chammas, Paul, Huang, Christine, Pratt-Kelly, Indigo, Koseki, Yoko, Nakayama, Manabu, Ishikura, Tomoyuki, Streubel, Gundula, Wynne, Kieran, Hokamp, Karsten, McLysaght, Aoife, Ciferri, Claudio, Di Croce, Luciano, Cagney, Gerard, Margueron, Raphaël, Koseki, Haruhiko, Bracken, Adrian P.
Published in Molecular cell (03.05.2018)
Published in Molecular cell (03.05.2018)
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Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing
Takada, Yuki, Yaman-Deveci, Ruken, Shirakawa, Takayuki, Sharif, Jafar, Tomizawa, Shin-Ichi, Miura, Fumihito, Ito, Takashi, Ono, Michio, Nakajima, Kuniko, Koseki, Yoko, Shiotani, Fuyuko, Ishiguro, Kei-Ichiro, Ohbo, Kazuyuki, Koseki, Haruhiko
Published in Development (Cambridge) (15.05.2021)
Published in Development (Cambridge) (15.05.2021)
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FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment
Dimitrova, Emilia, Kondo, Takashi, Feldmann, Angelika, Nakayama, Manabu, Koseki, Yoko, Konietzny, Rebecca, Kessler, Benedikt M, Koseki, Haruhiko, Klose, Robert J
Published in eLife (29.05.2018)
Published in eLife (29.05.2018)
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PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment
Takano, Junichiro, Ito, Shinsuke, Dong, Yixing, Sharif, Jafar, Nakajima-Takagi, Yaeko, Umeyama, Taichi, Han, Yong-Woon, Isono, Kyoichi, Kondo, Takashi, Iizuka, Yusuke, Miyai, Tomohiro, Koseki, Yoko, Ikegaya, Mika, Sakihara, Mizuki, Nakayama, Manabu, Ohara, Osamu, Hasegawa, Yoshinori, Hashimoto, Kosuke, Arner, Erik, Klose, Robert J., Iwama, Atsushi, Koseki, Haruhiko, Ikawa, Tomokatsu
Published in Nature communications (28.11.2022)
Published in Nature communications (28.11.2022)
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Ash1l methylates Lys36 of histone H3 independently of transcriptional elongation to counteract polycomb silencing
Miyazaki, Hitomi, Higashimoto, Ken, Yada, Yukari, Endo, Takaho A, Sharif, Jafar, Komori, Toshiharu, Matsuda, Masashi, Koseki, Yoko, Nakayama, Manabu, Soejima, Hidenobu, Handa, Hiroshi, Koseki, Haruhiko, Hirose, Susumu, Nishioka, Kenichi
Published in PLoS genetics (01.11.2013)
Published in PLoS genetics (01.11.2013)
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Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells
Satoh, Rumi, Kakugawa, Kiyokazu, Yasuda, Takuwa, Yoshida, Hisahiro, Sibilia, Maria, Katsura, Yoshimoto, Levi, Ben, Abramson, Jakub, Koseki, Yoko, Koseki, Haruhiko, van Ewijk, Willem, Hollander, Georg A, Kawamoto, Hiroshi
Published in PLoS genetics (01.01.2016)
Published in PLoS genetics (01.01.2016)
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Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice
Matsuda, Masashi, Ono, Rintaro, Iyoda, Tomonori, Endo, Takaho, Iwasaki, Makoto, Tomizawa-Murasawa, Mariko, Saito, Yoriko, Kaneko, Akiko, Shimizu, Kanako, Yamada, Daisuke, Ogonuki, Narumi, Watanabe, Takashi, Nakayama, Manabu, Koseki, Yoko, Kezuka-Shiotani, Fuyuko, Hasegawa, Takanori, Yabe, Hiromasa, Kato, Shunichi, Ogura, Atsuo, Shultz, Leonard D, Ohara, Osamu, Taniguchi, Masaru, Koseki, Haruhiko, Fujii, Shin-Ichiro, Ishikawa, Fumihiko
Published in Life science alliance (01.04.2019)
Published in Life science alliance (01.04.2019)
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Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages
Masui, Osamu, Corbel, Catherine, Nagao, Koji, Endo, Takaho A., Kezuka, Fuyuko, Diabangouaya, Patricia, Nakayama, Manabu, Kumon, Mami, Koseki, Yoko, Obuse, Chikashi, Koseki, Haruhiko, Heard, Edith
Published in Nature cell biology (01.01.2023)
Published in Nature cell biology (01.01.2023)
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Activation of Endogenous Retroviruses in Dnmt1−/− ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA
Sharif, Jafar, Endo, Takaho A., Nakayama, Manabu, Karimi, Mohammad M., Shimada, Midori, Katsuyama, Kayoko, Goyal, Preeti, Brind’Amour, Julie, Sun, Ming-An, Sun, Zhixiong, Ishikura, Tomoyuki, Mizutani-Koseki, Yoko, Ohara, Osamu, Shinkai, Yoichi, Nakanishi, Makoto, Xie, Hehuang, Lorincz, Matthew C., Koseki, Haruhiko
Published in Cell stem cell (07.07.2016)
Published in Cell stem cell (07.07.2016)
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RING1 contributes to early proximal-distal specification of the forelimb bud by restricting Meis2 expression
Yakushiji-Kaminatsui, Nayuta, Kondo, Takashi, Endo, Takaho A., Koseki, Yoko, Kondo, Kaori, Ohara, Osamu, Vidal, Miguel, Koseki, Haruhiko
Published in Development (Cambridge) (01.01.2015)
Published in Development (Cambridge) (01.01.2015)
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Regulation of Th2 Cell Differentiation by mel-18, a Mammalian Polycomb Group Gene
Kimura, Motoko, Koseki, Yoko, Yamashita, Masakatsu, Watanabe, Naohiro, Shimizu, Chiori, Katsumoto, Takuo, Kitamura, Toshio, Taniguchi, Masaru, Koseki, Haruhiko, Nakayama, Toshinori
Published in Immunity (Cambridge, Mass.) (01.08.2001)
Published in Immunity (Cambridge, Mass.) (01.08.2001)
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Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes
Li, Xiangzhi, Isono, Kyo-ichi, Yamada, Daisuke, Endo, Takaho A., Endoh, Mitsuhiro, Shinga, Jun, Mizutani-Koseki, Yoko, Otte, Arie P., Casanova, Miguel, Kitamura, Hiroshi, Kamijo, Takehiko, Sharif, Jafar, Ohara, Osamu, Toyada, Tetsuro, Bernstein, Bradley E., Brockdorff, Neil, Koseki, Haruhiko
Published in Molecular and Cellular Biology (01.01.2011)
Published in Molecular and Cellular Biology (01.01.2011)
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Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes
Isono, Kyo-ichi, Fujimura, Yu-ichi, Shinga, Jun, Yamaki, Makoto, O-Wang, Jiyang, Takihara, Yoshihiro, Murahashi, Yasuaki, Takada, Yuki, Mizutani-Koseki, Yoko, Koseki, Haruhiko
Published in Molecular and Cellular Biology (01.08.2005)
Published in Molecular and Cellular Biology (01.08.2005)
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Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
Blackledge, Neil P., Farcas, Anca M., Kondo, Takashi, King, Hamish W., McGouran, Joanna F., Hanssen, Lars L.P., Ito, Shinsuke, Cooper, Sarah, Kondo, Kaori, Koseki, Yoko, Ishikura, Tomoyuki, Long, Hannah K., Sheahan, Thomas W., Brockdorff, Neil, Kessler, Benedikt M., Koseki, Haruhiko, Klose, Robert J.
Published in Cell (01.06.2014)
Published in Cell (01.06.2014)
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Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8
Fujimura, Yu-ichi, Isono, Kyo-ichi, Vidal, Miguel, Endoh, Mitsuhiro, Kajita, Hiroshi, Mizutani-Koseki, Yoko, Takihara, Yoshihiro, van Lohuizen, Maarten, Otte, Arie, Jenuwein, Thomas, Deschamps, Jacqueline, Koseki, Haruhiko
Published in Development (Cambridge) (01.06.2006)
Published in Development (Cambridge) (01.06.2006)
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Identification, Tissue Expression, and Functional Characterization of Otx3, a Novel Member of the Otx Family
Zhang, Yan, Miki, Takashi, Iwanaga, Toshihiko, Koseki, Yoko, Okuno, Masaaki, Sunaga, Yasuhiro, Ozaki, Nobuaki, Yano, Hideki, Koseki, Haruhiko, Seino, Susumu
Published in The Journal of biological chemistry (02.08.2002)
Published in The Journal of biological chemistry (02.08.2002)
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