Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood−brain barrier permeability: Possible link to postoperative delirium and cognitive decline
Acharya, Nimish K, Goldwaser, Eric L, Forsberg, Martin M, Godsey, George A, Johnson, Cristina A, Sarkar, Abhirup, DeMarshall, Cassandra, Kosciuk, Mary C, Dash, Jacqueline M, Hale, Caitlin P, Leonard, Douglas M, Appelt, Denah M, Nagele, Robert G
Published in Brain research (16.09.2015)
Published in Brain research (16.09.2015)
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Journal Article
Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib
Acharya, Nimish K., Levin, Eli C., Clifford, Peter M., Han, Min, Tourtellotte, Ryan, Chamberlain, Dean, Pollaro, Michael, Coretti, Nicholas J., Kosciuk, Mary C., Nagele, Eric P., DeMarshall, Cassandra, Freeman, Theresa, Shi, Yi, Guan, Chenbing, Macphee, Colin H., Wilensky, Robert L., Nagele, Robert G.
Published in Journal of Alzheimer's disease (01.01.2013)
Published in Journal of Alzheimer's disease (01.01.2013)
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Journal Article
A Preliminary Report: The Hippocampus and Surrounding Temporal Cortex of Patients With Schizophrenia Have Impaired Blood-Brain Barrier
Goldwaser, Eric L, Swanson, 2nd, Randel L, Arroyo, Edgardo J, Venkataraman, Venkat, Kosciuk, Mary C, Nagele, Robert G, Hong, L Elliot, Acharya, Nimish K
Published in Frontiers in human neuroscience (31.03.2022)
Published in Frontiers in human neuroscience (31.03.2022)
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Journal Article
A Chronic Increase in Blood-Brain Barrier Permeability Facilitates Intraneuronal Deposition of Exogenous Bloodborne Amyloid-Beta1-42 Peptide in the Brain and Leads to Alzheimer's Disease-Relevant Cognitive Changes in a Mouse Model
Acharya, Nimish K, Grossman, Henya C, Clifford, Peter M, Levin, Eli C, Light, Kenneth R, Choi, Hana, Swanson Ii, Randel L, Kosciuk, Mary C, Venkataraman, Venkat, Libon, David J, Matzel, Louis D, Nagele, Robert G
Published in Journal of Alzheimer's disease (01.01.2024)
Published in Journal of Alzheimer's disease (01.01.2024)
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Journal Article
Evidence that Brain-Reactive Autoantibodies Contribute to Chronic Neuronal Internalization of Exogenous Amyloid-β1-42 and Key Cell Surface Proteins During Alzheimer's Disease Pathogenesis
Goldwaser, Eric L, Acharya, Nimish K, Wu, Hao, Godsey, George A, Sarkar, Abhirup, DeMarshall, Cassandra A, Kosciuk, Mary C, Nagele, Robert G
Published in Journal of Alzheimer's disease (2020)
Published in Journal of Alzheimer's disease (2020)
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Journal Article
Neuronal PAD4 expression and protein citrullination: Possible role in production of autoantibodies associated with neurodegenerative disease
Acharya, Nimish K, Nagele, Eric P, Han, Min, Coretti, Nicholas J, DeMarshall, Cassandra, Kosciuk, Mary C, Boulos, Paul A, Nagele, Robert G
Published in Journal of autoimmunity (01.06.2012)
Published in Journal of autoimmunity (01.06.2012)
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Journal Article
Selective affinity of extravasated brain‐reactive IgG autoantibodies for pyramidal neurons is linked to brain amyloid beta deposition, neuronal dysfunction, and cognitive decline
Acharya, Nimish K, Grossman, Henya, Rana, Dhara J, Arroyo, Edgardo, Swanson, Randel L, Kosciuk, Mary C, Venkataraman, Venkat, Bennett, David A., Arvanitakis, Zoe, Libon, David J, Nagele, Robert G.
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Mechanical stress regulates transport in a compliant 3D model of the blood-brain barrier
Partyka, Paul P, Godsey, George A, Galie, John R, Kosciuk, Mary C, Acharya, Nimish K, Nagele, Robert G, Galie, Peter A
Published in Biomaterials (01.01.2017)
Published in Biomaterials (01.01.2017)
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Journal Article
Retinal pathology is associated with increased blood–retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 inhibitor Darapladib
Acharya, Nimish K, Qi, Xin, Goldwaser, Eric L, Godsey, George A, Wu, Hao, Kosciuk, Mary C, Freeman, Theresa A, Macphee, Colin H, Wilensky, Robert L, Venkataraman, Venkat, Nagele, Robert G
Published in Diabetes & vascular disease research (01.05.2017)
Published in Diabetes & vascular disease research (01.05.2017)
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Journal Article
Aβ peptides can enter the brain through a defective blood–brain barrier and bind selectively to neurons
Clifford, Peter M, Zarrabi, Shabnam, Siu, Gilbert, Kinsler, Kristin J, Kosciuk, Mary C, Venkataraman, Venkateswar, D'Andrea, Michael R, Dinsmore, Steven, Nagele, Robert G
Published in Brain research (20.04.2007)
Published in Brain research (20.04.2007)
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Journal Article
Brain-Reactive Autoantibodies Prevalent in Human Sera Increase Intraneuronal Amyloid-β1-42 Deposition
Nagele, Robert G., Clifford, Peter M., Siu, Gilbert, Levin, Eli C., Acharya, Nimish K., Han, Min, Kosciuk, Mary C., Venkataraman, Venkat, Zavareh, Semah, Zarrabi, Shabnam, Kinsler, Kristin, Thaker, Nikhil G., Nagele, Eric P., Dash, Jacqueline, Wang, Hoau Y., Levitas, Andrew
Published in Journal of Alzheimer's disease (05.08.2011)
Published in Journal of Alzheimer's disease (05.08.2011)
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Journal Article
Brain-reactive autoantibodies prevalent in human sera increase intraneuronal amyloid-β(1-42) deposition
Nagele, Robert G, Clifford, Peter M, Siu, Gilbert, Levin, Eli C, Acharya, Nimish K, Han, Min, Kosciuk, Mary C, Venkataraman, Venkat, Zavareh, Semah, Zarrabi, Shabnam, Kinsler, Kristin, Thaker, Nikhil G, Nagele, Eric P, Dash, Jacqueline, Wang, Hoau Y, Levitas, Andrew
Published in Journal of Alzheimer's disease (2011)
Published in Journal of Alzheimer's disease (2011)
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Journal Article
P4-299: Neuron-binding autoantibodies in human sera enhance Abeta42 accumulation in adult mouse brain neurons
Nagele, Robert G, Clifford, Peter M, Levin, Eli C, Kosciuk, Mary C, Zarrabi, Shabnam, Venkataraman, Venkateswar, Kinsler, Kristin, Patel, Nikhil
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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Journal Article
Retinal pathology is associated with increased blood-retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA 2 inhibitor Darapladib
Acharya, Nimish K, Qi, Xin, Goldwaser, Eric L, Godsey, George A, Wu, Hao, Kosciuk, Mary C, Freeman, Theresa A, Macphee, Colin H, Wilensky, Robert L, Venkataraman, Venkat, Nagele, Robert G
Published in Diabetes & vascular disease research (01.05.2017)
Published in Diabetes & vascular disease research (01.05.2017)
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Journal Article
Natural IgG Autoantibodies Are Abundant and Ubiquitous in Human Sera, and Their Number Is Influenced By Age, Gender, and Disease. e60726
Nagele, Eric P, Han, Min, Acharya, Nimish K, DeMarshall, Cassandra, Kosciuk, Mary C, Nagele, Robert G
Published in PloS one (01.04.2013)
Published in PloS one (01.04.2013)
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Journal Article
Brain-Reactive Autoantibodies Prevalent in Human Sera Increase Intraneuronal Amyloid-1-42 Deposition
Nagele, Robert G, Clifford, Peter M, Siu, Gilbert, Levin, Eli C, Acharya, Nimish K, Han, Min, Kosciuk, Mary C, Venkataraman, Venkat, Zavareh, Semah, Zarrabi, Shabnam, Kinsler, Kristin, Thaker, Nikhil G, Nagele, Eric P, Dash, Jacqueline, Wang, Hoau Y, Levitas, Andrew
Published in Journal of Alzheimer's disease (01.01.2011)
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Published in Journal of Alzheimer's disease (01.01.2011)
Journal Article
Abeta peptides can enter the brain through a defective blood-brain barrier and bind selectively to neurons
Clifford, Peter M, Zarrabi, Shabnam, Siu, Gilbert, Kinsler, Kristin J, Kosciuk, Mary C, Venkataraman, Venkateswar, D'Andrea, Michael R, Dinsmore, Steven, Nagele, Robert G
Published in Brain research (20.04.2007)
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Published in Brain research (20.04.2007)
Journal Article
P3-285 Antibodies targeting the GLU-R2 subunit of the Ampa receptor: a key role for autoimmunity in Alzheimer's disease
Nagele, Robert G., D'Andrea, Michael R., Siu, Gilbert, Venkataraman, Venkateswar, Kosciuk, Mary C., Wang, Hoau-Yan
Published in Neurobiology of aging (01.07.2004)
Published in Neurobiology of aging (01.07.2004)
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