Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity
Hornung, Michael W, Korte, Joseph J, Olker, Jennifer H, Denny, Jeffrey S, Knutsen, Carsten, Hartig, Phillip C, Cardon, Mary C, Degitz, Sigmund J
Published in Toxicological sciences (01.04.2018)
Published in Toxicological sciences (01.04.2018)
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Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases
Olker, Jennifer H, Korte, Joseph J, Denny, Jeffrey S, Hartig, Phillip C, Cardon, Mary C, Knutsen, Carsten N, Kent, Paige M, Christensen, Jessica P, Degitz, Sigmund J, Hornung, Michael W
Published in Toxicological sciences (01.04.2019)
Published in Toxicological sciences (01.04.2019)
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Progress towards Development of an Amphibian-Based Thyroid Screening Assay Using Xenopus laevis. Organismal and Thyroidal Responses to the Model Compounds 6-Propylthiouracil, Methimazole, and Thyroxine
Degitz, Sigmund J., Holcombe, Gary W., Flynn, Kevin M., Kosian, Patricia A., Korte, Joseph J., Tietge, Joseph E.
Published in Toxicological sciences (01.10.2005)
Published in Toxicological sciences (01.10.2005)
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Thyroid-stimulating hormone (TSH): Measurement of intracellular, secreted, and circulating hormone in Xenopus laevis and Xenopus tropicalis
Korte, Joseph J, Sternberg, Robin M, Serrano, Jose A, Thoemke, Kara R, Moen, Scott M, Lillegard, Kathryn E, Hornung, Michael W, Tietge, Joseph E, Degitz, Sigmund J
Published in General and comparative endocrinology (01.05.2011)
Published in General and comparative endocrinology (01.05.2011)
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Metamorphic inhibition of Xenopus laevis by sodium perchlorate: Effects on development and thyroid histology
Tietge, Joseph E., Holcombe, Gary W., Flynn, Kevin M., Kosian, Patricia A., Korte, Joseph J., Anderson, Leroy E., Wolf, Douglas C., Degitz, Sigmund J.
Published in Environmental toxicology and chemistry (01.04.2005)
Published in Environmental toxicology and chemistry (01.04.2005)
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In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles
Hornung, Michael W, Kosian, Patricia A, Haselman, Jonathan T, Korte, Joseph J, Challis, Katie, Macherla, Chitralekha, Nevalainen, Erica, Degitz, Sigmund J
Published in Toxicological sciences (01.08.2015)
Published in Toxicological sciences (01.08.2015)
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Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus laevis Using Iopanoic Acid
Haselman, Jonathan T, Olker, Jennifer H, Kosian, Patricia A, Korte, Joseph J, Denny, Jeffrey S, Tietge, Joseph E, Hornung, Michael W, Degitz, Sigmund J
Published in Toxicological sciences (26.04.2022)
Published in Toxicological sciences (26.04.2022)
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In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase
Olker, Jennifer H., Korte, Joseph J., Denny, Jeffrey S., Haselman, Jonathan T., Hartig, Phillip C., Cardon, Mary C., Hornung, Michael W., Degitz, Sigmund J.
Published in Toxicology in vitro (01.03.2021)
Published in Toxicology in vitro (01.03.2021)
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Targeted Pathway-based In Vivo Testing Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model Amphibian Xenopus laevis
Haselman, Jonathan T, Olker, Jennifer H, Kosian, Patricia A, Korte, Joseph J, Swintek, Joseph A, Denny, Jeffrey S, Nichols, John W, Tietge, Joseph E, Hornung, Michael W, Degitz, Sigmund J
Published in Toxicological sciences (01.06.2020)
Published in Toxicological sciences (01.06.2020)
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Journal Article
Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals
Mayasich, Sally A., Korte, Joseph J., Denny, Jeffrey S., Hartig, Phillip C., Olker, Jennifer H., DeGoey, Philip, O’Flanagan, Joseph, Degitz, Sigmund J., Hornung, Michael W.
Published in Toxicology in vitro (01.06.2021)
Published in Toxicology in vitro (01.06.2021)
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Journal Article
Evaluating Iodide Recycling Inhibition as a Novel Molecular Initiating Event for Thyroid Axis Disruption in Amphibians
Olker, Jennifer H, Haselman, Jonathan T, Kosian, Patricia A, Donnay, Kelby G, Korte, Joseph J, Blanksma, Chad, Hornung, Michael W, Degitz, Sigmund J
Published in Toxicological sciences (01.12.2018)
Published in Toxicological sciences (01.12.2018)
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Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis: Manifestations of antiandrogenic and other modes of toxicity
Haselman, Jonathan T., Kosian, Patricia A., Korte, Joseph J., Olmstead, Allen W., Degitz, Sigmund J.
Published in Aquatic toxicology (01.06.2018)
Published in Aquatic toxicology (01.06.2018)
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Journal Article
Development of the Larval Amphibian Growth and Development Assay: effects of chronic 4-tert-octylphenol or 17β-trenbolone exposure in Xenopus laevis from embryo to juvenile
Haselman, Jonathan T., Kosian, Patricia A., Korte, Joseph J., Olmstead, Allen W., Iguchi, Taisen, Johnson, Rodney D., Degitz, Sigmund J.
Published in Journal of applied toxicology (01.12.2016)
Published in Journal of applied toxicology (01.12.2016)
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Journal Article
Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole
Tietge, Joseph E., Degitz, Sigmund J., Haselman, Jonathan T., Butterworth, Brian C., Korte, Joseph J., Kosian, Patricia A., Lindberg-Livingston, Annelie J., Burgess, Emily M., Blackshear, Pamela E., Hornung, Michael W.
Published in Aquatic toxicology (15.01.2013)
Published in Aquatic toxicology (15.01.2013)
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Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile
Haselman, Jonathan T., Sakurai, Maki, Watanabe, Naoko, Goto, Yasushi, Onishi, Yuta, Ito, Yuki, Onoda, Yu, Kosian, Patricia A., Korte, Joseph J., Johnson, Rodney D., Iguchi, Taisen, Degitz, Sigmund J.
Published in Journal of applied toxicology (01.12.2016)
Published in Journal of applied toxicology (01.12.2016)
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