New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan
Khomenko, Tatyana M, Zakharenko, Alexandra L, Kornienko, Tatyana E, Chepanova, Arina A, Dyrkheeva, Nadezhda S, Artemova, Anastasia O, Korchagina, Dina V, Achara, Chigozie, Curtis, Anthony, Reynisson, Jóhannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (23.05.2023)
Published in International journal of molecular sciences (23.05.2023)
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New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling
Salomatina, Oksana V, Kornienko, Tatyana E, Zakharenko, Alexandra L, Komarova, Nina I, Achara, Chigozie, Reynisson, Jóhannes, Salakhutdinov, Nariman F, Lavrik, Olga I, Volcho, Konstantin P
Published in Molecules (Basel, Switzerland) (01.01.2024)
Published in Molecules (Basel, Switzerland) (01.01.2024)
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Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives
Kornienko, Tatyana E, Chepanova, Arina A, Zakharenko, Alexandra L, Filimonov, Aleksandr S, Luzina, Olga A, Dyrkheeva, Nadezhda S, Nikolin, Valeriy P, Popova, Nelly A, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.01.2024)
Published in International journal of molecular sciences (01.01.2024)
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The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo
Chernyshova, Irina A, Zakharenko, Aleksandra L, Kurochkin, Nikolay N, Dyrkheeva, Nadezhda S, Kornienko, Tatyana E, Popova, Nelly A, Nikolin, Valeriy P, Ilina, Ekaterina S, Zharkov, Timofey D, Kupryushkin, Maxim S, Oslovsky, Vladimir E, Drenichev, Mikhail S, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (31.12.2022)
Published in Molecules (Basel, Switzerland) (31.12.2022)
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Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties
Ivankin, Dmitry I, Kornienko, Tatyana E, Mikhailova, Marina A, Dyrkheeva, Nadezhda S, Zakharenko, Alexandra L, Achara, Chigozie, Reynisson, Jóhannes, Golyshev, Victor M, Luzina, Olga A, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1
Dyrkheeva, Nadezhda S, Filimonov, Aleksandr S, Luzina, Olga A, Orlova, Kristina A, Chernyshova, Irina A, Kornienko, Tatyana E, Malakhova, Anastasia A, Medvedev, Sergey P, Zakharenko, Alexandra L, Ilina, Ekaterina S, Anarbaev, Rashid O, Naumenko, Konstantin N, Klabenkova, Kristina V, Burakova, Ekaterina A, Stetsenko, Dmitry A, Zakian, Suren M, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in International journal of molecular sciences (20.10.2021)
Published in International journal of molecular sciences (20.10.2021)
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Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan
Munkuev, Aldar A, Dyrkheeva, Nadezhda S, Kornienko, Tatyana E, Ilina, Ekaterina S, Ivankin, Dmitry I, Suslov, Evgeniy V, Korchagina, Dina V, Gatilov, Yuriy V, Zakharenko, Alexandra L, Malakhova, Anastasia A, Reynisson, Jóhannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I
Published in Molecules (Basel, Switzerland) (24.05.2022)
Published in Molecules (Basel, Switzerland) (24.05.2022)
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Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan
Okhina, Alina A., Kornienko, Tatyana E., Rogachev, Artem D., Luzina, Olga A., Popova, Nelly A., Nikolin, Valery P., Zakharenko, Alexandra L., Dyrkheeva, Nadezhda S., Pokrovsky, Andrey G., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Journal of pharmaceutical and biomedical analysis (30.11.2023)
Published in Journal of pharmaceutical and biomedical analysis (30.11.2023)
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Synthesis of adamantane-monoterpene conjugates with 1,3,4-thiadiazol-2(3H)-imine linker and evaluation of their inhibitory activity against TDP1
Munkuev, Aldar A., Zakharenko, Alexandra L., Kornienko, Tatyana E., Dyrkheeva, Nadezhda S., Ilina, Ekaterina S., Suslov, Evgeniy V., Issa, Fatima, Achara, Chigozie, Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.
Published in Medicinal chemistry research (01.02.2024)
Published in Medicinal chemistry research (01.02.2024)
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