Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
Bi, Junfeng, Ichu, Taka-Aki, Zanca, Ciro, Yang, Huijun, Zhang, Wei, Gu, Yuchao, Chowdhry, Sudhir, Reed, Alex, Ikegami, Shiro, Turner, Kristen M., Zhang, Wenjing, Villa, Genaro R., Wu, Sihan, Quehenberger, Oswald, Yong, William H., Kornblum, Harley I., Rich, Jeremy N., Cloughesy, Timothy F., Cavenee, Webster K., Furnari, Frank B., Cravatt, Benjamin F., Mischel, Paul S.
Published in Cell metabolism (03.09.2019)
Published in Cell metabolism (03.09.2019)
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Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes
Li, Jiwen, Pan, Lin, Pembroke, William G, Rexach, Jessica E, Godoy, Marlesa I, Condro, Michael C, Alvarado, Alvaro G, Harteni, Mineli, Chen, Yen-Wei, Stiles, Linsey, Chen, Angela Y, Wanner, Ina B, Yang, Xia, Goldman, Steven A, Geschwind, Daniel H, Kornblum, Harley I, Zhang, Ye
Published in Nature communications (25.06.2021)
Published in Nature communications (25.06.2021)
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Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection
Kaneko, Naoki, Satta, Sandro, Komuro, Yutaro, Muthukrishnan, Sree Deepthi, Kakarla, Visesha, Guo, Lea, An, Jennifer, Elahi, Fanny, Kornblum, Harley I, Liebeskind, David S, Hsiai, Tzung, Hinman, Jason D
Published in Stroke (1970) (01.01.2021)
Published in Stroke (1970) (01.01.2021)
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Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
Turner, Kristen M, Deshpande, Viraj, Beyter, Doruk, Koga, Tomoyuki, Rusert, Jessica, Lee, Catherine, Li, Bin, Arden, Karen, Ren, Bing, Nathanson, David A, Kornblum, Harley I, Taylor, Michael D, Kaushal, Sharmeela, Cavenee, Webster K, Wechsler-Reya, Robert, Furnari, Frank B, Vandenberg, Scott R, Rao, P Nagesh, Wahl, Geoffrey M, Bafna, Vineet, Mischel, Paul S
Published in Nature (London) (02.03.2017)
Published in Nature (London) (02.03.2017)
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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
Nathanson, David A., Gini, Beatrice, Mottahedeh, Jack, Visnyei, Koppany, Koga, Tomoyuki, Gomez, German, Estin, Ascia, Hwang, Kiwook, Wang, Jun, Masui, Kenta, Paucar, Andres, Yang, Huijun, Ohashi, Minori, Zhu, Shaojun, Wykosky, Jill, Reed, Rachel, Nelson, Stanley F., Cloughesy, Timothy F., James, C. David, Rao, P. Nagesh, Kornblum, Harley I., Heath, James R., Cavenee, Webster K., Furnari, Frank B., Mischel, Paul S.
Published in Science (American Association for the Advancement of Science) (03.01.2014)
Published in Science (American Association for the Advancement of Science) (03.01.2014)
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CD44v6 regulates growth of brain tumor stem cells partially through the AKT-mediated pathway
Jijiwa, Mayumi, Demir, Habibe, Gupta, Snehalata, Leung, Crystal, Joshi, Kaushal, Orozco, Nicholas, Huang, Tiffany, Yildiz, Vedat O, Shibahara, Ichiyo, de Jesus, Jason A, Yong, William H, Mischel, Paul S, Fernandez, Soledad, Kornblum, Harley I, Nakano, Ichiro
Published in PloS one (06.09.2011)
Published in PloS one (06.09.2011)
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P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells
Muthukrishnan, Sree Deepthi, Kawaguchi, Riki, Nair, Pooja, Prasad, Rachna, Qin, Yue, Johnson, Maverick, Wang, Qing, VanderVeer-Harris, Nathan, Pham, Amy, Alvarado, Alvaro G, Condro, Michael C, Gao, Fuying, Gau, Raymond, Castro, Maria G, Lowenstein, Pedro R, Deb, Arjun, Hinman, Jason D, Pajonk, Frank, Burns, Terry C, Goldman, Steven A, Geschwind, Daniel H, Kornblum, Harley I
Published in Nature communications (19.10.2022)
Published in Nature communications (19.10.2022)
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Dopamine Receptor Antagonists, Radiation, and Cholesterol Biosynthesis in Mouse Models of Glioblastoma
Bhat, Kruttika, Saki, Mohammad, Cheng, Fei, He, Ling, Zhang, Le, Ioannidis, Angeliki, Nathanson, David, Tsang, Jonathan, Bensinger, Steven J, Nghiemphu, Phioanh Leia, Cloughesy, Timothy F, Liau, Linda M, Kornblum, Harley I, Pajonk, Frank
Published in JNCI : Journal of the National Cancer Institute (02.08.2021)
Published in JNCI : Journal of the National Cancer Institute (02.08.2021)
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Alternative RNA splicing modulates ribosomal composition and determines the spatial phenotype of glioblastoma cells
Larionova, Tatyana D, Bastola, Soniya, Aksinina, Tatiana E, Anufrieva, Ksenia S, Wang, Jia, Shender, Victoria O, Andreev, Dmitriy E, Kovalenko, Tatiana F, Arapidi, Georgij P, Shnaider, Polina V, Kazakova, Anastasia N, Latyshev, Yaroslav A, Tatarskiy, Victor V, Shtil, Alexander A, Moreau, Pascale, Giraud, Francis, Li, Chaoxi, Wang, Yichan, Rubtsova, Maria P, Dontsova, Olga A, Condro, Michael, Ellingson, Benjamin M, Shakhparonov, Mikhail I, Kornblum, Harley I, Nakano, Ichiro, Pavlyukov, Marat S
Published in Nature cell biology (01.10.2022)
Published in Nature cell biology (01.10.2022)
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Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner
Le Belle, Janel E., Orozco, Nicolas M., Paucar, Andres A., Saxe, Jonathan P., Mottahedeh, Jack, Pyle, April D., Wu, Hong, Kornblum, Harley I.
Published in Cell stem cell (07.01.2011)
Published in Cell stem cell (07.01.2011)
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Nicotinamide Adenine Dinucleotide Phosphate Oxidase Promotes Glioblastoma Radiation Resistance in a Phosphate and Tensin Homolog-Dependent Manner
Ludwig, Kirsten, Le Belle, Janel E, Muthukrishnan, Sree Deepthi, Sperry, Jantzen, Condro, Michael, Vlashi, Erina, Pajonk, Frank, Kornblum, Harley I
Published in Antioxidants & redox signaling (01.11.2023)
Published in Antioxidants & redox signaling (01.11.2023)
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MELK‐Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells
Joshi, Kaushal, Banasavadi‐Siddegowda, Yeshavanth, Mo, Xiaokui, Kim, Sung‐Hak, Mao, Ping, Kig, Cenk, Nardini, Diana, Sobol, Robert W., Chow, Lionel M.L., Kornblum, Harley I., Waclaw, Ronald, Beullens, Monique, Nakano, Ichiro
Published in Stem cells (Dayton, Ohio) (01.06.2013)
Published in Stem cells (Dayton, Ohio) (01.06.2013)
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Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2
Wang, Jia, Cheng, Peng, Pavlyukov, Marat S, Yu, Hai, Zhang, Zhuo, Kim, Sung-Hak, Minata, Mutsuko, Mohyeldin, Ahmed, Xie, Wanfu, Chen, Dongquan, Goidts, Violaine, Frett, Brendan, Hu, Wenhao, Li, Hongyu, Shin, Yong Jae, Lee, Yeri, Nam, Do-Hyun, Kornblum, Harley I, Wang, Maode, Nakano, Ichiro
Published in The Journal of clinical investigation (01.08.2017)
Published in The Journal of clinical investigation (01.08.2017)
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Neural Stem Cells (NSCs) and Proteomics
Shoemaker, Lorelei D., Kornblum, Harley I.
Published in Molecular & cellular proteomics (01.02.2016)
Published in Molecular & cellular proteomics (01.02.2016)
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pH-Weighted amine chemical exchange saturation transfer echo planar imaging visualizes infiltrating glioblastoma cells
Patel, Kunal S, Yao, Jingwen, Cho, Nicholas S, Sanvito, Francesco, Tessema, Kaleab, Alvarado, Alvaro, Dudley, Lindsey, Rodriguez, Fausto, Everson, Richard, Cloughesy, Timothy F, Salamon, Noriko, Liau, Linda M, Kornblum, Harley I, Ellingson, Benjamin M
Published in Neuro-oncology (Charlottesville, Va.) (05.01.2024)
Published in Neuro-oncology (Charlottesville, Va.) (05.01.2024)
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Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition
Minata, Mutsuko, Gu, Chunyu, Joshi, Kaushal, Nakano-Okuno, Mariko, Hong, Christopher, Nguyen, Chi-Hung, Kornblum, Harley I, Molla, Annie, Nakano, Ichiro
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Effects of Brain Irradiation in Immune-Competent and Immune-Compromised Mouse Models
Saki, Mohammad, Bhat, Kruttika, Sodhi, Sirajbir S, Nguyen, Nhan T, Kornblum, Harley I, Pajonk, Frank
Published in Radiation research (01.02.2020)
Published in Radiation research (01.02.2020)
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