Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma
Unger, Gretchen M, Kren, Betsy T, Korman, Vicci L, Kimbrough, Tyler G, Vogel, Rachel I, Ondrey, Frank G, Trembley, Janeen H, Ahmed, Khalil
Published in Molecular cancer therapeutics (01.08.2014)
Published in Molecular cancer therapeutics (01.08.2014)
Get full text
Journal Article
Tenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in mice
Trembley, Janeen H, Unger, Gretchen M, Korman, Vicci L, Abedin, Md Joynal, Nacusi, Lucas P, Vogel, Rachel I, Slaton, Joel W, Kren, Betsy T, Ahmed, Khalil
Published in PloS one (15.10.2014)
Published in PloS one (15.10.2014)
Get full text
Journal Article
Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells
Trembley, Janeen H, Unger, Gretchen M, Korman, Vicci L, Tobolt, Diane K, Kazimierczuk, Zygmunt, Pinna, Lorenzo A, Kren, Betsy T, Ahmed, Khalil
Published in Cancer letters (01.02.2012)
Published in Cancer letters (01.02.2012)
Get full text
Journal Article
Abstract 3746: A high dose priming strategy with the novel RNAi therapeutic GS-10 elevates RISC Ago2, Ago4 and GW182 protein levels to enhance RNAi efficacy in a metastatic solid tumor model
Nacusi, Lucas P., Korman, Vicci L., Pretti, Alex J., Tobolt, Diane K., Mendoza, Alvaro, Unger, Gretchen M.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Get full text
Journal Article
CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors
Ahmed, Khalil, Kren, Betsy T, Abedin, Md Joynal, Vogel, Rachel I, Shaughnessy, Daniel P, Nacusi, Lucas, Korman, Vicci L, Li, Yingming, Dehm, Scott M, Zimmerman, Cheryl L, Niehans, Gloria A, Unger, Gretchen M, Trembley, Janeen H
Published in Oncotarget (20.09.2016)
Published in Oncotarget (20.09.2016)
Get full text
Journal Article
Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α′ subunits reduces orthotopic xenograft prostate tumors in mice
Trembley, Janeen H., Unger, Gretchen M., Tobolt, Diane K., Korman, Vicci L., Wang, Guixia, Ahmad, Kashif A., Slaton, Joel W., Kren, Betsy T., Ahmed, Khalil
Published in Molecular and cellular biochemistry (01.10.2011)
Published in Molecular and cellular biochemistry (01.10.2011)
Get full text
Journal Article
Tenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation
Trembley, Janeen H, Unger, Gretchen M, Gomez, Omar Cespedes, Abedin, J, Korman, Vicci L, Vogel, Rachel I, Niehans, Gloria, Kren, Betsy T, Ahmed, Khalil
Published in Molecular and cellular pharmacology (Windsor Mill, Md.) (2014)
Published in Molecular and cellular pharmacology (Windsor Mill, Md.) (2014)
Get full text
Journal Article
Structural Dynamics of the Actin–Myosin Interface by Site-directed Spectroscopy
Korman, Vicci L., Anderson, Sarah E.B., Prochniewicz, Ewa, Titus, Margaret A., Thomas, David D.
Published in Journal of molecular biology (10.03.2006)
Published in Journal of molecular biology (10.03.2006)
Get full text
Journal Article
Systemic administration of antisense oligonucleotides simultaneously targeting CK2[alpha] and [alpha]' subunits reduces orthotopic xenograft prostate tumors in mice
Trembley, Janeen H, Unger, Gretchen M, Tobolt, Diane K, Korman, Vicci L, Wang, Guixia, Ahmad, Kashif A, Slaton, Joel W, Kren, Betsy T, Ahmed, Khalil
Published in Molecular and cellular biochemistry (01.10.2011)
Published in Molecular and cellular biochemistry (01.10.2011)
Get full text
Journal Article
Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice: e109970
Trembley, Janeen H, Unger, Gretchen M, Korman, Vicci L, Abedin, Joynal, Nacusi, Lucas P, Vogel, Rachel I, Slaton, Joel W, Kren, Betsy T, Ahmed, Khalil
Published in PloS one (01.10.2014)
Published in PloS one (01.10.2014)
Get full text
Journal Article
SYSTEMS AND METHODS FOR DETECTING GENETIC VARIATION IN NUCLEIC ACIDS
WANG, Wei, NELSON, Matthew, STUYVENBERG, Ian, SU, Yi-Hsuan, MENDOSA, Gemma Roselle, KLEIN, Todd Michael, SONG, Jung Min, KORMAN, Vicci L
Year of Publication 27.09.2023
Get full text
Year of Publication 27.09.2023
Patent
SYSTEMS AND METHODS FOR DETECTING GENETIC VARIATION IN NUCLEIC ACIDS
WANG, Wei, NELSON, Matthew, STUYVENBERG, Ian, SU, Yi-Hsuan, MENDONSA, Gemma Roselle, KLEIN, Todd Michael, SONG, Jung Min, KORMAN, Vicci L
Year of Publication 29.09.2022
Get full text
Year of Publication 29.09.2022
Patent
SYSTEMS AND METHODS FOR DETECTING GENETIC VARIATION IN NUCLEIC ACIDS
WANG, Wei, NELSON, Matthew, STUYVENBERG, Ian, SU, Yi-Hsuan, MENDOSA, Gemma Roselle, KLEIN, Todd Michael, SONG, Jung Min, KORMAN, Vicci L
Year of Publication 20.07.2022
Get full text
Year of Publication 20.07.2022
Patent
SYSTEMS AND METHODS FOR DETECTING GENETIC VARIATION IN NUCLEIC ACIDS
WANG, Wei, NELSON, Matthew, STUYVENBERG, Ian, SU, Yi-Hsuan, MENDOSA, Gemma Roselle, KLEIN, Todd Michael, SONG, Jung Min, KORMAN, Vicci L
Year of Publication 18.03.2021
Get full text
Year of Publication 18.03.2021
Patent