An hiPSC‐based genetic screening system to model aggregation of tau protein allows the identification and validation of possible targets for Alzheimer’s disease therapies
Reinhardt, Peter, Guillen, Nathalie, Untucht, Christopher, Ried, Janina S., Manos, Justine, Geist, Daniela, Korffmann, Juergen, Cik, Miroslav, Lakics, Viktor
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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An hiPSC‐based genetic screening system to model aggregation of tau protein allows the identification and validation of possible targets for Alzheimer’s disease therapies: Nonhuman/Target identification and validation studies: Tau
Reinhardt, Peter, Guillen, Nathalie, Untucht, Christopher, Ried, Janina S., Manos, Justine, Geist, Daniela, Korffmann, Juergen, Cik, Miroslav, Lakics, Viktor
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation
Reinhardt, Lydia, Musacchio, Fabrizio, Bichmann, Maria, Behrendt, Annika, Ercan-Herbst, Ebru, Stein, Juliane, Becher, Isabelle, Haberkant, Per, Mader, Julia, Schöndorf, David C., Schmitt, Melanie, Korffmann, Jürgen, Reinhardt, Peter, Pohl, Christian, Savitski, Mikhail, Klein, Corinna, Gasparini, Laura, Fuhrmann, Martin, Ehrnhoefer, Dagmar E.
Published in Neurobiology of disease (15.06.2023)
Published in Neurobiology of disease (15.06.2023)
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Generating Human iPSC-Derived Astrocytes with Chemically Defined Medium for In Vitro Disease Modeling
Janssen, Katharina, Bahnassawy, Lamiaa, Kiefer, Claudia, Korffmann, Jürgen, Terstappen, Georg C, Lakics, Viktor, Cik, Miroslav, Reinhardt, Peter
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Identification of APOE phenotypes in microglia and neurons derived from isogenic hips cells: A study of the IMI ADAPTED consortium
Bahnassawy, Lamiaa, Buchheit, Johanna, Curado, Marco Rocha, Ried, Janina S., Sáez, María Eugenia, Nicolas, Armel, Rao, Francesco, Kaplan, Charlotte, Mohler, Eric G., Lee, Heyne, Untucht, Christopher, Korffmann, Juergen, Lakics, Viktor, Cik, Miroslav, Grezella, Clara, Brustle, Oliver, Peitz, Michael, Mañes, Santos, Ramaswamy, Gayathri, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Reinhardt, Peter
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Identification of APOE phenotypes in microglia and neurons derived from isogenic hips cells: A study of the IMI ADAPTED consortium: Molecular and cell biology/stem cells, iPS cells
Bahnassawy, Lamiaa, Buchheit, Johanna, Curado, Marco Rocha, Ried, Janina S., Sáez, María Eugenia, Nicolas, Armel, Rao, Francesco, Kaplan, Charlotte, Mohler, Eric G., Lee, Heyne, Untucht, Christopher, Korffmann, Juergen, Lakics, Viktor, Cik, Miroslav, Grezella, Clara, Brustle, Oliver, Peitz, Michael, Mañes, Santos, Ramaswamy, Gayathri, Socorro, Alfredo Cabrera, Bakker, Margot H.M., Reinhardt, Peter
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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P4‐057: MODELING ALZHEIMER'S DISEASE PATHOPHYSIOLOGY USING ISOGENIC HUMAN APOE IPSC‐DERIVED NEURAL CELLS
Bahnassawy, Lamiaa, Reinhardt, Peter, Korffmann, Juergen, Kiefer, Claudia, Cik, Miroslav, Mohler, Eric G., Ried, Janina S., Lakics, Viktor, Bakker, Margot H.M.
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Establishment of a high-content imaging assay for tau aggregation in hiPSC-derived neurons differentiated from two protocols to routinely evaluate compounds and genetic perturbations
Bahnassawy, Lamiaa, Nicolaisen, Nathalie, Untucht, Christopher, Mielich-Süss, Benjamin, Reinhardt, Lydia, Ried, Janina S., Morawe, Martina P., Geist, Daniela, Finck, Anja, Käfer, Elke, Korffmann, Jürgen, Townsend, Matthew, Ravikumar, Brinda, Lakics, Viktor, Cik, Miroslav, Reinhardt, Peter
Published in SLAS discovery (01.03.2024)
Published in SLAS discovery (01.03.2024)
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