An oncogenic enhancer encodes selective selenium dependency in AML
Eagle, Kenneth, Jiang, Yajian, Shi, Xiangguo, Li, Minhua, Obholzer, Nikolaus D., Hu, Tianyuan, Perez, Monika W., Koren, Jošt Vrabič, Kitano, Ayumi, Yi, Joanna S., Lin, Charles Y., Nakada, Daisuke
Published in Cell stem cell (03.03.2022)
Published in Cell stem cell (03.03.2022)
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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
Richters, André, Doyle, Shelby K., Freeman, David B., Lee, Christina, Leifer, Becky S., Jagannathan, Sajjeev, Kabinger, Florian, Koren, Jošt Vrabič, Struntz, Nicholas B., Urgiles, Julie, Stagg, Ryan A., Curtin, Brice H., Chatterjee, Deep, Mathea, Sebastian, Mikochik, Peter J., Hopkins, Tamara D., Gao, Hua, Branch, Jonathan R., Xin, Hong, Westover, Lori, Bignan, Gilles C., Rupnow, Brent A., Karlin, Kristen L., Olson, Calla M., Westbrook, Thomas F., Vacca, Joseph, Wilfong, Chris M., Trotter, B. Wesley, Saffran, Douglas C., Bischofberger, Norbert, Knapp, Stefan, Russo, Joshua W., Hickson, Ian, Bischoff, James R., Gottardis, Marco M., Balk, Steven P., Lin, Charles Y., Pop, Marius S., Koehler, Angela N.
Published in Cell chemical biology (18.02.2021)
Published in Cell chemical biology (18.02.2021)
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Transcriptional Plasticity Drives Leukemia Immune Escape
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Published in Blood cancer discovery (06.09.2022)
Published in Blood cancer discovery (06.09.2022)
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A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia
Harada, Taku, Heshmati, Yaser, Kalfon, Jérémie, Perez, Monika W, Xavier Ferrucio, Juliana, Ewers, Jazmin, Hubbell Engler, Benjamin, Kossenkov, Andrew, Ellegast, Jana M, Yi, Joanna S, Bowker, Allyson, Zhu, Qian, Eagle, Kenneth, Liu, Tianxin, Kai, Yan, Dempster, Joshua M, Kugener, Guillaume, Wickramasinghe, Jayamanna, Herbert, Zachary T, Li, Charles H, Vrabič Koren, Jošt, Weinstock, David M, Paralkar, Vikram R, Nabet, Behnam, Lin, Charles Y, Dharia, Neekesh V, Stegmaier, Kimberly, Orkin, Stuart H, Pimkin, Maxim
Published in Genes & development (01.03.2022)
Published in Genes & development (01.03.2022)
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Abstract 1771: Targeting oncogenic transcription in prostate cancer with a novel, oral bioavailable, and ultra-selective CDK9 inhibitor
Richters, André, Freeman, David, Lee, Christina, Kabinger, Florian, Doyle, Shelby, Leifer, Becky, Mikochik, Peter, Jagannathan, Sajjeev, Koren, Jost Vrabic, Karlin, Kristen, Olson, Calla M., Wilfong, Christopher, Lin, Charles Y., Saffran, Doug, Vacca, Joseph, Bischofberger, Norbert, Pop, Marius, Koehler, Angela N.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency
Perez, Monika W., Sias-Garcia, Oscar, Daramola, Alfred, Wei, Helen, Terrell, Maci, Rashid, Raushan, Park, Woojun D., Duong, Kevin, Horton, Terzah M., Li, Feng, Cherayil, Nikitha, Koren, Jost Vrabic, Gant, Vincent U., Junco, Jacob J., Curry, Choladda V., Stevens, Alexandra M., Lin, Charles Y., Yi, Joanna S.
Published in Blood advances (14.12.2021)
Published in Blood advances (14.12.2021)
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Transcriptional plasticity drives leukemia immune escape
Eagle, Kenneth, Harada, Taku, Kalfon, Jeremie, Perez, Monika, Heshmati, Yaser, Ewers, Jazmin, Koren, Jost Vrabic, Dempster, Joshua M, Kugener, Guillaume, Paralkar, Vikram R, Lin, Charles Y, Dharia, Neekesh V, Stegmaier, Kimberly, Orkin, Stuart H, Pimkin, Maxim
Published in bioRxiv (24.08.2021)
Published in bioRxiv (24.08.2021)
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Paper
A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia
Harada, Taku, Heshmati, Yaser, Kalfon, Jeremie, Ferrucio, Juliana Xavier, Perez, Monika, Ewers, Jazmin, Kossenkov, Andrew, Ellegast, Jana M, Yi, Joanna S, Bowker, Allyson, Zhu, Qian, Eagle, Kenneth, Dempster, Joshua M, Kugener, Guillaume, Wickramasinghe, Jayamanna, Herbert, Zachary T, Li, Charles H, Koren, Jost Vrabic, Weinstock, David M, Paralkar, Vikram R, Nabet, Behnam, Lin, Charles Y, Dharia, Neekesh V, Stegmaier, Kimberly, Orkin, Stuart H, Pimkin, Maxim
Published in bioRxiv (04.08.2021)
Published in bioRxiv (04.08.2021)
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Paper
An oncogenic enhancer encodes selective selenium dependency in AML
Eagle, Kenneth, Jiang, Yajian, Shi, Xiangguo, Li, Minhua, Obholzer, Nikolaus D, Hu, Tianyuan, Perez, Monika W, Koren, Jošt Vrabič, Kitano, Ayumi, Yi, Joanna S, Lin, Charles Y, Nakada, Daisuke
Published in Cell stem cell (07.04.2022)
Published in Cell stem cell (07.04.2022)
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