Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer
Font-Burgada, Joan, Shalapour, Shabnam, Ramaswamy, Suvasini, Hsueh, Brian, Rossell, David, Umemura, Atsushi, Taniguchi, Koji, Nakagawa, Hayato, Valasek, Mark A., Ye, Li, Kopp, Janel L., Sander, Maike, Carter, Hannah, Deisseroth, Karl, Verma, Inder M., Karin, Michael
Published in Cell (13.08.2015)
Published in Cell (13.08.2015)
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Journal Article
Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
Kopp, Janel L., von Figura, Guido, Mayes, Erin, Liu, Fen-Fen, Dubois, Claire L., Morris, John P., Pan, Fong Cheng, Akiyama, Haruhiko, Wright, Christopher V.E., Jensen, Kristin, Hebrok, Matthias, Sander, Maike
Published in Cancer cell (11.12.2012)
Published in Cancer cell (11.12.2012)
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Journal Article
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
De Vas, Matias G, Kopp, Janel L, Heliot, Claire, Sander, Maike, Cereghini, Silvia, Haumaitre, Cécile
Published in Development (Cambridge) (01.03.2015)
Published in Development (Cambridge) (01.03.2015)
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Journal Article
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis
Rockich, Briana E, Hrycaj, Steven M, Shih, Hung Ping, Nagy, Melinda S, Ferguson, Michael A H, Kopp, Janel L, Sander, Maike, Wellik, Deneen M, Spence, Jason R
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2013)
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Journal Article
Small Increases in the Level of Sox2 Trigger the Differentiation of Mouse Embryonic Stem Cells
Kopp, Janel L., Ormsbee, Briana D., Desler, Michelle, Rizzino, Angie
Published in Stem cells (Dayton, Ohio) (01.04.2008)
Published in Stem cells (Dayton, Ohio) (01.04.2008)
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Journal Article
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation
Shih, Hung Ping, Kopp, Janel L, Sandhu, Manbir, Dubois, Claire L, Seymour, Philip A, Grapin-Botton, Anne, Sander, Maike
Published in Development (Cambridge) (15.07.2012)
Published in Development (Cambridge) (15.07.2012)
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Journal Article
Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice
Kopp, Janel L., Dubois, Claire L., Schaeffer, David F., Samani, Atefeh, Taghizadeh, Farnaz, Cowan, Robert W., Rhim, Andrew D., Stiles, Bangyan L., Valasek, Mark, Sander, Maike
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2018)
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Journal Article
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
Fox, Raymond G, Lytle, Nikki K, Jaquish, Dawn V, Park, Frederick D, Ito, Takahiro, Bajaj, Jeevisha, Koechlein, Claire S, Zimdahl, Bryan, Yano, Masato, Kopp, Janel, Kritzik, Marcie, Sicklick, Jason, Sander, Maike, Grandgenett, Paul M, Hollingsworth, Michael A, Shibata, Shinsuke, Pizzo, Donald, Valasek, Mark, Sasik, Roman, Scadeng, Miriam, Okano, Hideyuki, Kim, Youngsoo, MacLeod, A Robert, Lowy, Andrew M, Reya, Tannishtha
Published in Nature (London) (16.06.2016)
Published in Nature (London) (16.06.2016)
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Journal Article
Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice
Dorrell, Craig, Erker, Laura, Schug, Jonathan, Kopp, Janel L, Canaday, Pamela S, Fox, Alan J, Smirnova, Olga, Duncan, Andrew W, Finegold, Milton J, Sander, Maike, Kaestner, Klaus H, Grompe, Markus
Published in Genes & development (01.06.2011)
Published in Genes & development (01.06.2011)
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Journal Article
Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells
Carpentier, Rodolphe, Suñer, Regina Español, van Hul, Noémi, Kopp, Janel L, Beaudry, Jean–Bernard, Cordi, Sabine, Antoniou, Aline, Raynaud, Peggy, Lepreux, Sébastien, Jacquemin, Patrick, Leclercq, Isabelle A, Sander, Maike, Lemaigre, Frédéric P
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2011)
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Journal Article
Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration
Barrionuevo, Francisco J, Hurtado, Alicia, Kim, Gwang-Jin, Real, Francisca M, Bakkali, Mohammed, Kopp, Janel L, Sander, Maike, Scherer, Gerd, Burgos, Miguel, Jiménez, Rafael
Published in eLife (21.06.2016)
Published in eLife (21.06.2016)
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Journal Article
Progenitor cell domains in the developing and adult pancreas
Kopp, Janel L., Dubois, Claire L., Hao, Ergeng, Thorel, Fabrizio, Herrera, Pedro L., Sander, Maike
Published in Cell cycle (Georgetown, Tex.) (15.06.2011)
Published in Cell cycle (Georgetown, Tex.) (15.06.2011)
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Journal Article
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
Tixi, Wilma, Maldonado, Maricela, Chang, Ya-Ting, Chiu, Amy, Yeung, Wilson, Parveen, Nazia, Nelson, Michael S, Hart, Ryan, Wang, Shihao, Hsu, Wu Jih, Fueger, Patrick, Kopp, Janel L, Huising, Mark O, Dhawan, Sangeeta, Shih, Hung Ping
Published in eLife (23.08.2023)
Published in eLife (23.08.2023)
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Journal Article
PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response
Ye, Jie, Huang, Anpei, Wang, Haitao, Zhang, Anni M Y, Huang, Xiaojun, Lan, Qingping, Sato, Tomohiko, Goyama, Susumu, Kurokawa, Mineo, Deng, Chuxia, Sander, Maike, Schaeffer, David F, Li, Wen, Kopp, Janel L, Xie, Ruiyu
Published in Cell death & disease (16.03.2020)
Published in Cell death & disease (16.03.2020)
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Journal Article
Effects of hyperinsulinemia on pancreatic cancer development and the immune microenvironment revealed through single-cell transcriptomics
Zhang, Anni M Y, Chu, Ken H, Daly, Brian F, Ruiter, Titine, Dou, Yan, Yang, Jenny C C, de Winter, Twan J J, Chhuor, Justin, Wang, Su, Flibotte, Stephane, Zhao, Yiwei Bernie, Hu, Xiaoke, Li, Hong, Rideout, Elizabeth J, Schaeffer, David F, Johnson, James D, Kopp, Janel L
Published in Cancer & metabolism (21.02.2022)
Published in Cancer & metabolism (21.02.2022)
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Journal Article
Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice
Erener, Suheda, Ellis, Cara E., Ramzy, Adam, Glavas, Maria M., O’Dwyer, Shannon, Pereira, Sandra, Wang, Tom, Pang, Janice, Bruin, Jennifer E., Riedel, Michael J., Baker, Robert K., Webber, Travis D., Lesina, Marina, Blüher, Matthias, Algül, Hana, Kopp, Janel L., Herzig, Stephan, Kieffer, Timothy J.
Published in Cell reports. Medicine (16.11.2021)
Published in Cell reports. Medicine (16.11.2021)
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Journal Article
Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma
Lee, Alex Y L, Dubois, Claire L, Sarai, Karnjit, Zarei, Soheila, Schaeffer, David F, Sander, Maike, Kopp, Janel L
Published in Gut (01.03.2019)
Published in Gut (01.03.2019)
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Journal Article
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
Kopp, Janel L, Dubois, Claire L, Schaffer, Ashleigh E, Hao, Ergeng, Shih, Hung Ping, Seymour, Philip A, Ma, Jenny, Sander, Maike
Published in Development (Cambridge) (15.02.2011)
Published in Development (Cambridge) (15.02.2011)
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Journal Article