Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale
Liew, Fungmin Eric, Nogle, Robert, Abdalla, Tanus, Rasor, Blake J., Canter, Christina, Jensen, Rasmus O., Wang, Lan, Strutz, Jonathan, Chirania, Payal, De Tissera, Sashini, Mueller, Alexander P., Ruan, Zhenhua, Gao, Allan, Tran, Loan, Engle, Nancy L., Bromley, Jason C., Daniell, James, Conrado, Robert, Tschaplinski, Timothy J., Giannone, Richard J., Hettich, Robert L., Karim, Ashty S., Simpson, Séan D., Brown, Steven D., Leang, Ching, Jewett, Michael C., Köpke, Michael
Published in Nature biotechnology (01.03.2022)
Published in Nature biotechnology (01.03.2022)
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Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria
Vögeli, Bastian, Schulz, Luca, Garg, Shivani, Tarasava, Katia, Clomburg, James M., Lee, Seung Hwan, Gonnot, Aislinn, Moully, Elamar Hakim, Kimmel, Blaise R., Tran, Loan, Zeleznik, Hunter, Brown, Steven D., Simpson, Sean D., Mrksich, Milan, Karim, Ashty S., Gonzalez, Ramon, Köpke, Michael, Jewett, Michael C.
Published in Nature communications (01.06.2022)
Published in Nature communications (01.06.2022)
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In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design
Karim, Ashty S., Dudley, Quentin M., Juminaga, Alex, Yuan, Yongbo, Crowe, Samantha A., Heggestad, Jacob T., Garg, Shivani, Abdalla, Tanus, Grubbe, William S., Rasor, Blake J., Coar, David N., Torculas, Maria, Krein, Michael, Liew, FungMin (Eric), Quattlebaum, Amy, Jensen, Rasmus O., Stuart, Jeffrey A., Simpson, Sean D., Köpke, Michael, Jewett, Michael C.
Published in Nature chemical biology (01.08.2020)
Published in Nature chemical biology (01.08.2020)
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Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation
Fackler, Nick, Heijstra, Björn D, Rasor, Blake J, Brown, Hunter, Martin, Jacob, Ni, Zhuofu, Shebek, Kevin M, Rosin, Rick R, Simpson, Séan D, Tyo, Keith E, Giannone, Richard J, Hettich, Robert L, Tschaplinski, Timothy J, Leang, Ching, Brown, Steven D, Jewett, Michael C, Köpke, Michael
Published in Annual review of chemical and biomolecular engineering (07.06.2021)
Published in Annual review of chemical and biomolecular engineering (07.06.2021)
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Agr Quorum Sensing influences the Wood-Ljungdahl pathway in Clostridium autoethanogenum
Piatek, Pawel, Humphreys, Christopher, Raut, Mahendra P., Wright, Phillip C., Simpson, Sean, Köpke, Michael, Minton, Nigel P., Winzer, Klaus
Published in Scientific reports (10.01.2022)
Published in Scientific reports (10.01.2022)
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Low carbon fuels and commodity chemicals from waste gases - systematic approach to understand energy metabolism in a model acetogen
Marcellin, Esteban, Behrendorff, James B, Nagaraju, Shilpa, DeTissera, Sashini, Segovia, Simon, Palfreyman, Robin W, Daniell, James, Licona-Cassani, Cuauhtemoc, Quek, Lake-ee, Speight, Robert, Hodson, Mark P, Simpson, Sean D, Mitchell, Wayne P, Köpke, Michael, Nielsen, Lars K
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2016)
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2016)
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An alcove at the acetyl-CoA synthase nickel active site is required for productive substrate CO binding and anaerobic carbon fixation
Wiley, Seth, Griffith, Claire, Eckert, Peter, Mueller, Alexander P., Nogle, Robert, Simpson, Séan D., Köpke, Michael, Can, Mehmet, Sarangi, Ritimukta, Kubarych, Kevin, Ragsdale, Stephen W.
Published in The Journal of biological chemistry (01.08.2024)
Published in The Journal of biological chemistry (01.08.2024)
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Enhancing CO2-Valorization Using Clostridium autoethanogenum for Sustainable Fuel and Chemicals Production
Heffernan, James K., Valgepea, Kaspar, de Souza Pinto Lemgruber, Renato, Casini, Isabella, Plan, Manuel, Tappel, Ryan, Simpson, Sean D., Köpke, Michael, Nielsen, Lars K., Marcellin, Esteban
Published in Frontiers in bioengineering and biotechnology (27.03.2020)
Published in Frontiers in bioengineering and biotechnology (27.03.2020)
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Required Gene Set for Autotrophic Growth of Clostridium autoethanogenum
Woods, Craig, Humphreys, Christopher M, Tomi-Andrino, Claudio, Henstra, Anne M, Köpke, Michael, Simpson, Sean D, Winzer, Klaus, Minton, Nigel P
Published in Applied and environmental microbiology (12.04.2022)
Published in Applied and environmental microbiology (12.04.2022)
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Systems-level engineering and characterisation of Clostridium autoethanogenum through heterologous production of poly-3-hydroxybutyrate (PHB)
de Souza Pinto Lemgruber, Renato, Valgepea, Kaspar, Tappel, Ryan, Behrendorff, James B., Palfreyman, Robin William, Plan, Manuel, Hodson, Mark P., Simpson, Séan Dennis, Nielsen, Lars K., Köpke, Michael, Marcellin, Esteban
Published in Metabolic engineering (01.05.2019)
Published in Metabolic engineering (01.05.2019)
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Ten simple rules for managing laboratory information
Berezin, Casey-Tyler, Aguilera, Luis U, Billerbeck, Sonja, Bourne, Philip E, Densmore, Douglas, Freemont, Paul, Gorochowski, Thomas E, Hernandez, Sarah I, Hillson, Nathan J, King, Connor R, Köpke, Michael, Ma, Shuyi, Miller, Katie M, Moon, Tae Seok, Moore, Jason H, Munsky, Brian, Myers, Chris J, Nicholas, Dequina A, Peccoud, Samuel J, Zhou, Wen, Peccoud, Jean
Published in PLoS computational biology (01.12.2023)
Published in PLoS computational biology (01.12.2023)
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Development of a clostridia-based cell-free system for prototyping genetic parts and metabolic pathways
Krüger, Antje, Mueller, Alexander P., Rybnicky, Grant A., Engle, Nancy L., Yang, Zamin K., Tschaplinski, Timothy J., Simpson, Sean D., Köpke, Michael, Jewett, Michael C.
Published in Metabolic engineering (01.11.2020)
Published in Metabolic engineering (01.11.2020)
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Maintenance of ATP Homeostasis Triggers Metabolic Shifts in Gas-Fermenting Acetogens
Valgepea, Kaspar, de Souza Pinto Lemgruber, Renato, Meaghan, Kieran, Palfreyman, Robin William, Abdalla, Tanus, Heijstra, Björn Daniel, Behrendorff, James Bruce, Tappel, Ryan, Köpke, Michael, Simpson, Séan Dennis, Nielsen, Lars Keld, Marcellin, Esteban
Published in Cell systems (24.05.2017)
Published in Cell systems (24.05.2017)
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Reconstruction of an acetogenic 2,3-butanediol pathway involving a novel NADPH-dependent primary-secondary alcohol dehydrogenase
Köpke, Michael, Gerth, Monica L, Maddock, Danielle J, Mueller, Alexander P, Liew, FungMin, Simpson, Séan D, Patrick, Wayne M
Published in Applied and Environmental Microbiology (01.06.2014)
Published in Applied and Environmental Microbiology (01.06.2014)
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A novel conjugal donor strain for improved DNA transfer into Clostridium spp
Woods, Craig, Humphreys, Christopher M., Rodrigues, Raquel Mesquita, Ingle, Patrick, Rowe, Peter, Henstra, Anne M., Köpke, Michael, Simpson, Sean D., Winzer, Klaus, Minton, Nigel P.
Published in Anaerobe (01.10.2019)
Published in Anaerobe (01.10.2019)
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The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases
Pander, Bart, Harris, Gemma, Scott, David J., Winzer, Klaus, Köpke, Michael, Simpson, Sean D., Minton, Nigel P., Henstra, Anne M.
Published in Applied microbiology and biotechnology (01.09.2019)
Published in Applied microbiology and biotechnology (01.09.2019)
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Faster Growth Enhances Low Carbon Fuel and Chemical Production Through Gas Fermentation
de Lima, Lorena Azevedo, Ingelman, Henri, Brahmbhatt, Kush, Reinmets, Kristina, Barry, Craig, Harris, Audrey, Marcellin, Esteban, Köpke, Michael, Valgepea, Kaspar
Published in Frontiers in bioengineering and biotechnology (12.04.2022)
Published in Frontiers in bioengineering and biotechnology (12.04.2022)
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Journal Article
Absolute Proteome Quantification in the Gas-Fermenting Acetogen Clostridium autoethanogenum
Valgepea, Kaspar, Talbo, Gert, Takemori, Nobuaki, Takemori, Ayako, Ludwig, Christina, Mahamkali, Vishnuvardhan, Mueller, Alexander P, Tappel, Ryan, Köpke, Michael, Simpson, Séan Dennis, Nielsen, Lars Keld, Marcellin, Esteban
Published in mSystems (26.04.2022)
Published in mSystems (26.04.2022)
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Journal Article
Gas fermentation for microbial sustainable aviation fuel production
Rodriguez, Karen, Pedroso, Marcelo, Harris, Audrey, Garg, Shivani, Hine, Damian, Köpke, Michael, Schenk, Gerhard, Marcellin, Esteban
Published in Microbiology Australia (01.01.2023)
Published in Microbiology Australia (01.01.2023)
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A TetR-Family Protein (CAETHG_0459) Activates Transcription From a New Promoter Motif Associated With Essential Genes for Autotrophic Growth in Acetogens
de Souza Pinto Lemgruber, Renato, Valgepea, Kaspar, Gonzalez Garcia, Ricardo Axayacatl, de Bakker, Christopher, Palfreyman, Robin William, Tappel, Ryan, Köpke, Michael, Simpson, Séan Dennis, Nielsen, Lars Keld, Marcellin, Esteban
Published in Frontiers in microbiology (15.11.2019)
Published in Frontiers in microbiology (15.11.2019)
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