Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation
Koopman, Werner J H, Nijtmans, Leo G J, Dieteren, Cindy E J, Roestenberg, Peggy, Valsecchi, Federica, Smeitink, Jan A M, Willems, Peter H G M
Published in Antioxidants & redox signaling (15.06.2010)
Published in Antioxidants & redox signaling (15.06.2010)
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A ratiometric fluorescent probe for assessing mitochondrial phospholipid peroxidation within living cells
Prime, Tracy A., Forkink, Marleen, Logan, Angela, Finichiu, Peter G., McLachlan, Jennifer, Li Pun, Pamela Boon, Koopman, Werner J.H., Larsen, Lesley, Latter, Melissa J., Smith, Robin A.J., Murphy, Michael P.
Published in Free radical biology & medicine (01.08.2012)
Published in Free radical biology & medicine (01.08.2012)
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Identification of Mitochondrial Complex I Assembly Intermediates by Tracing Tagged NDUFS3 Demonstrates the Entry Point of Mitochondrial Subunits
Vogel, Rutger O., Dieteren, Cindy E.J., van den Heuvel, Lambert P. W.J., Willems, Peter H. G.M., Smeitink, Jan A.M., Koopman, Werner J.H., Nijtmans, Leo G.J.
Published in The Journal of biological chemistry (09.03.2007)
Published in The Journal of biological chemistry (09.03.2007)
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Journal Article
Subunits of Mitochondrial Complex I Exist as Part of Matrix- and Membrane-associated Subcomplexes in Living Cells
Dieteren, Cindy E.J., Willems, Peter H.G.M., Vogel, Rutger O., Swarts, Herman G., Fransen, Jack, Roepman, Ronald, Crienen, Gijs, Smeitink, Jan A.M., Nijtmans, Leo G.J., Koopman, Werner J.H.
Published in The Journal of biological chemistry (12.12.2008)
Published in The Journal of biological chemistry (12.12.2008)
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Journal Article
Monogenic Mitochondrial Disorders
Koopman, Werner J.H, Willems, Peter H.G.M, Smeitink, Jan A.M
Published in The New England journal of medicine (22.03.2012)
Published in The New England journal of medicine (22.03.2012)
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Journal Article
Defective mitochondrial translation differently affects the live cell dynamics of complex I subunits
Dieteren, Cindy E.J., Willems, Peter H.G.M., Swarts, Herman G., Fransen, Jack, Smeitink, Jan A.M., Koopman, Werner J.H., Nijtmans, Leo G.J.
Published in Biochimica et biophysica acta (01.12.2011)
Published in Biochimica et biophysica acta (01.12.2011)
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Journal Article
Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition
Schirris, Tom J.J., Renkema, G. Herma, Ritschel, Tina, Voermans, Nicol C., Bilos, Albert, van Engelen, Baziel G.M., Brandt, Ulrich, Koopman, Werner J.H., Beyrath, Julien D., Rodenburg, Richard J., Willems, Peter H.G.M., Smeitink, Jan A.M., Russel, Frans G.M.
Published in Cell metabolism (01.09.2015)
Published in Cell metabolism (01.09.2015)
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The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
Keating, Samuel T., Groh, Laszlo, van der Heijden, Charlotte D.C.C., Rodriguez, Hanah, dos Santos, Jéssica C., Fanucchi, Stephanie, Okabe, Jun, Kaipananickal, Harikrishnan, van Puffelen, Jelmer H., Helder, Leonie, Noz, Marlies P., Matzaraki, Vasiliki, Li, Yang, de Bree, L. Charlotte J., Koeken, Valerie A.C.M., Moorlag, Simone J.C.F.M., Mourits, Vera P., Domínguez-Andrés, Jorge, Oosting, Marije, Bulthuis, Elianne P., Koopman, Werner J.H., Mhlanga, Musa, El-Osta, Assam, Joosten, Leo A.B., Netea, Mihai G., Riksen, Niels P.
Published in Cell reports (Cambridge) (21.04.2020)
Published in Cell reports (Cambridge) (21.04.2020)
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Journal Article
Redox Homeostasis and Mitochondrial Dynamics
Willems, Peter H.G.M., Rossignol, Rodrigue, Dieteren, Cindy E.J., Murphy, Michael P., Koopman, Werner J.H.
Published in Cell metabolism (04.08.2015)
Published in Cell metabolism (04.08.2015)
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Journal Article
Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease
Distelmaier, Felix, Koopman, Werner J.H., van den Heuvel, Lambertus P., Rodenburg, Richard J., Mayatepek, Ertan, Willems, Peter H.G.M., Smeitink, Jan A.M.
Published in Brain (London, England : 1878) (01.04.2009)
Published in Brain (London, England : 1878) (01.04.2009)
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Dimethyl itaconate induces long-term innate immune responses and confers protection against infection
Ferreira, Anaísa V., Kostidis, Sarantos, Groh, Laszlo A., Koeken, Valerie A.C.M., Bruno, Mariolina, Baydemir, Ilayda, Kilic, Gizem, Bulut, Özlem, Andriopoulou, Theano, Spanou, Victoria, Synodinou, Kalliopi D., Gkavogianni, Theologia, Moorlag, Simone J.C.F.M., Charlotte de Bree, L., Mourits, Vera P., Matzaraki, Vasiliki, Koopman, Werner J.H., van de Veerdonk, Frank L., Renieris, Georgios, Giera, Martin, Giamarellos-Bourboulis, Evangelos J., Novakovic, Boris, Domínguez-Andrés, Jorge
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V
Forkink, Marleen, Manjeri, Ganesh R., Liemburg-Apers, Dania C., Nibbeling, Esther, Blanchard, Maxime, Wojtala, Aleksandra, Smeitink, Jan A.M., Wieckowski, Mariusz R., Willems, Peter H.G.M., Koopman, Werner J.H.
Published in Biochimica et biophysica acta (01.08.2014)
Published in Biochimica et biophysica acta (01.08.2014)
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Journal Article
Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells
Forkink, Marleen, Basit, Farhan, Teixeira, José, Swarts, Herman G, Koopman, Werner J H, Willems, Peter H G M
Published in Redox biology (01.12.2015)
Published in Redox biology (01.12.2015)
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Journal Article
Variants in NGLY1 lead to intellectual disability, myoclonus epilepsy, sensorimotor axonal polyneuropathy and mitochondrial dysfunction
Panneman, Daan M., Wortmann, Saskia B., Haaxma, Charlotte A., Hasselt, Peter M., Wolf, Nicole I., Hendriks, Yvonne, Küsters, Benno, Emst‐de Vries, Sjenet, Westerlo, Els, Koopman, Werner J.H., Wintjes, Liesbeth, Brandt, Frans, Vries, Maaike, Lefeber, Dirk J., Smeitink, Jan A.M., Rodenburg, Richard J.
Published in Clinical genetics (01.04.2020)
Published in Clinical genetics (01.04.2020)
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Journal Article
Frapbot: An open‐source application for FRAP data
Kohze, Robin, Dieteren, Cindy E.J., Koopman, Werner J.H., Brock, Roland, Schmidt, Samuel
Published in Cytometry. Part A (01.08.2017)
Published in Cytometry. Part A (01.08.2017)
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Journal Article
Rotenone inhibits primary murine myotube formation via Raf-1 and ROCK2
Grefte, Sander, Wagenaars, Jori A.L., Jansen, Renate, Willems, Peter H.G.M., Koopman, Werner J.H.
Published in Biochimica et biophysica acta (01.07.2015)
Published in Biochimica et biophysica acta (01.07.2015)
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