A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
Lehne, Benjamin, Drong, Alexander W, Loh, Marie, Zhang, Weihua, Scott, William R, Tan, Sian-Tsung, Afzal, Uzma, Scott, James, Jarvelin, Marjo-Riitta, Elliott, Paul, McCarthy, Mark I, Kooner, Jaspal S, Chambers, John C
Published in Genome Biology (15.02.2015)
Published in Genome Biology (15.02.2015)
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Association analyses based on false discovery rate implicate new loci for coronary artery disease
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Published in Nature genetics (01.09.2017)
Published in Nature genetics (01.09.2017)
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Contribution of lower physical activity levels to higher risk of insulin resistance and associated metabolic disturbances in South Asians compared to Europeans
Afaq, Saima, Kooner, Angad S, Loh, Marie, Kooner, Jaspal S, Chambers, John C
Published in PloS one (07.05.2019)
Published in PloS one (07.05.2019)
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Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes
Yaghootkar, Hanieh, Scott, Robert A, White, Charles C, Zhang, Weihua, Speliotes, Elizabeth, Munroe, Patricia B, Ehret, Georg B, Bis, Joshua C, Fox, Caroline S, Walker, Mark, Borecki, Ingrid B, Knowles, Joshua W, Yerges-Armstrong, Laura, Ohlsson, Claes, Perry, John R B, Chambers, John C, Kooner, Jaspal S, Franceschini, Nora, Langenberg, Claudia, Hivert, Marie-France, Dastani, Zari, Richards, J Brent, Semple, Robert K, Frayling, Timothy M
Published in Diabetes (New York, N.Y.) (01.12.2014)
Published in Diabetes (New York, N.Y.) (01.12.2014)
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Common genetic variation near MC4R is associated with waist circumference and insulin resistance
Kooner, Jaspal S, Chambers, John C, Elliott, Paul, Zabaneh, Delilah, Zhang, Weihua, Li, Yun, Froguel, Philippe, Balding, David, Scott, James
Published in Nature genetics (01.06.2008)
Published in Nature genetics (01.06.2008)
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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
Hawe, Johann S., Wilson, Rory, Schmid, Katharina T., Zhou, Li, Lakshmanan, Lakshmi Narayanan, Lehne, Benjamin C., Kühnel, Brigitte, Scott, William R., Wielscher, Matthias, Yew, Yik Weng, Baumbach, Clemens, Lee, Dominic P., Marouli, Eirini, Bernard, Manon, Pfeiffer, Liliane, Matías-García, Pamela R., Autio, Matias I., Bourgeois, Stephane, Herder, Christian, Karhunen, Ville, Meitinger, Thomas, Prokisch, Holger, Rathmann, Wolfgang, Roden, Michael, Sebert, Sylvain, Shin, Jean, Strauch, Konstantin, Zhang, Weihua, Tan, Wilson L. W., Hauck, Stefanie M., Merl-Pham, Juliane, Grallert, Harald, Barbosa, Eudes G. V., Illig, Thomas, Peters, Annette, Paus, Tomas, Pausova, Zdenka, Deloukas, Panos, Foo, Roger S. Y., Jarvelin, Marjo-Riitta, Kooner, Jaspal S., Loh, Marie, Heinig, Matthias, Gieger, Christian, Waldenberger, Melanie, Chambers, John C.
Published in Nature genetics (01.01.2022)
Published in Nature genetics (01.01.2022)
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Alcohol consumption is associated with widespread changes in blood DNA methylation: Analysis of cross‐sectional and longitudinal data
Dugué, Pierre‐Antoine, Wilson, Rory, Lehne, Benjamin, Jayasekara, Harindra, Wang, Xiaochuan, Jung, Chol‐Hee, Joo, JiHoon E., Makalic, Enes, Schmidt, Daniel F., Baglietto, Laura, Severi, Gianluca, Gieger, Christian, Ladwig, Karl‐Heinz, Peters, Annette, Kooner, Jaspal S., Southey, Melissa C., English, Dallas R., Waldenberger, Melanie, Chambers, John C., Giles, Graham G., Milne, Roger L.
Published in Addiction biology (01.01.2021)
Published in Addiction biology (01.01.2021)
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Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study
Cardona, Alexia, Day, Felix R, Perry, John R B, Loh, Marie, Chu, Audrey Y, Lehne, Benjamin, Paul, Dirk S, Lotta, Luca A, Stewart, Isobel D, Kerrison, Nicola D, Scott, Robert A, Khaw, Kay-Tee, Forouhi, Nita G, Langenberg, Claudia, Liu, Chunyu, Mendelson, Michael M, Levy, Daniel, Beck, Stephan, Leslie, R David, Dupuis, Josée, Meigs, James B, Kooner, Jaspal S, Pihlajamäki, Jussi, Vaag, Allan, Perfilyev, Alexander, Ling, Charlotte, Hivert, Marie-France, Chambers, John C, Wareham, Nicholas J, Ong, Ken K
Published in Diabetes (New York, N.Y.) (01.12.2019)
Published in Diabetes (New York, N.Y.) (01.12.2019)
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Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
McAllan, Liam, Baranasic, Damir, Villicaña, Sergio, Brown, Scarlett, Zhang, Weihua, Lehne, Benjamin, Adamo, Marco, Jenkinson, Andrew, Elkalaawy, Mohamed, Mohammadi, Borzoueh, Hashemi, Majid, Fernandes, Nadia, Lambie, Nathalie, Williams, Richard, Christiansen, Colette, Yang, Youwen, Zudina, Liudmila, Lagou, Vasiliki, Tan, Sili, Castillo-Fernandez, Juan, King, James W. D., Soong, Richie, Elliott, Paul, Scott, James, Prokopenko, Inga, Cebola, Inês, Loh, Marie, Lenhard, Boris, Batterham, Rachel L., Bell, Jordana T., Chambers, John C., Kooner, Jaspal S., Scott, William R.
Published in Nature communications (15.05.2023)
Published in Nature communications (15.05.2023)
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A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides
Braun, Timothy R, Been, Latonya F, Singhal, Akhil, Worsham, Jacob, Ralhan, Sarju, Wander, Gurpreet S, Chambers, John C, Kooner, Jaspal S, Aston, Christopher E, Sanghera, Dharambir K
Published in PloS one (18.05.2012)
Published in PloS one (18.05.2012)
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Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts
Fraszczyk, Eliza, Spijkerman, Annemieke M. W., Zhang, Yan, Brandmaier, Stefan, Day, Felix R., Zhou, Li, Wackers, Paul, Dollé, Martijn E. T., Bloks, Vincent W., Gào, Xīn, Gieger, Christian, Kooner, Jaspal, Kriebel, Jennifer, Picavet, H. Susan J., Rathmann, Wolfgang, Schöttker, Ben, Loh, Marie, Verschuren, W. M. Monique, van Vliet-Ostaptchouk, Jana V., Wareham, Nicholas J., Chambers, John C., Ong, Ken K., Grallert, Harald, Brenner, Hermann, Luijten, Mirjam, Snieder, Harold
Published in Diabetologia (01.05.2022)
Published in Diabetologia (01.05.2022)
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Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes
Yuan, Xin, Waterworth, Dawn, Perry, John R.B., Lim, Noha, Song, Kijoung, Chambers, John C., Zhang, Weihua, Vollenweider, Peter, Stirnadel, Heide, Johnson, Toby, Bergmann, Sven, Beckmann, Noam D., Li, Yun, Ferrucci, Luigi, Melzer, David, Hernandez, Dena, Singleton, Andrew, Scott, James, Elliott, Paul, Waeber, Gerard, Cardon, Lon, Frayling, Timothy M., Kooner, Jaspal S., Mooser, Vincent
Published in American journal of human genetics (01.10.2008)
Published in American journal of human genetics (01.10.2008)
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Investigation of Genetic Variation Underlying Central Obesity amongst South Asians
Scott, William R, Zhang, Weihua, Loh, Marie, Tan, Sian-Tsung, Lehne, Benjamin, Afzal, Uzma, Peralta, Juan, Saxena, Richa, Ralhan, Sarju, Wander, Gurpreet S, Bozaoglu, Kiymet, Sanghera, Dharambir K, Elliott, Paul, Scott, James, Chambers, John C, Kooner, Jaspal S
Published in PloS one (19.05.2016)
Published in PloS one (19.05.2016)
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Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics
Tynkkynen, Tuulia, Wang, Qin, Ekholm, Jussi, Anufrieva, Olga, Ohukainen, Pauli, Vepsäläinen, Jouko, Männikkö, Minna, Keinänen-Kiukaanniemi, Sirkka, Holmes, Michael V, Goodwin, Matthew, Ring, Susan, Chambers, John C, Kooner, Jaspal, Järvelin, Marjo-Riitta, Kettunen, Johannes, Hill, Michael, Davey Smith, George, Ala-Korpela, Mika
Published in International journal of epidemiology (01.06.2019)
Published in International journal of epidemiology (01.06.2019)
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Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India
SAXENA, Richa, SALEHEEN, Danish, SIM, Xueling, HASSANALI, Neelam, RADHA, Venkatesan, CHIDAMBARAM, Manickam, LIJU, Samuel, REES, Simon D, NG, Daniel Peng-Keat, WONG, Tien-Yin, YAMAUCHI, Toshimasa, HARA, Kazuo, BEEN, Latonya F, TANAKA, Yasushi, HIROSE, Hiroshi, MCCARTHY, Mark I, MORRIS, Andrew P, BASIT, Abdul, BARNETT, Anthony H, KATULANDA, Prasad, MATTHEWS, David, MOHAN, Viswanathan, WANDER, Gurpreet S, GARAVITO, Martha L, JAI RUP SINGH, MEHRA, Narinder K, RALHAN, Sarju, ILYAS KAMBOH, M, MULVIHILL, John J, MAEGAWA, Hiroshi, TOBE, Kazuyuki, MAEDA, Shiro, CHO, Yoon S, SHYONG TAI, E, BRAUN, Timothy, KELLY, M. Ann, CHAMBERS, John C, KOONER, Jaspal S, KADOWAKI, Takashi, DELOUKAS, Panos, RADER, Daniel J, DANESH, John, SANGHERA, Dharambir K, BJONNES, Andrew, ROBIN YOUNG, WEANG KEE HO, RASHEED, Asif, FROSSARD, Philippe
Published in Diabetes (New York, N.Y.) (01.05.2013)
Published in Diabetes (New York, N.Y.) (01.05.2013)
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Reference equations for evaluation of spirometry function tests in South Asia, and among South Asians living in other countries
Leong, Wei Yee, Gupta, Ananya, Hasan, Mehedi, Mahmood, Sara, Siddiqui, Samreen, Ahmed, Sajjad, Goon, Ian Y, Loh, Marie, Mina, Theresia H, Lam, Benjamin, Yew, Yik Weng, Ngeow, Joanne, Lee, Jimmy, Lee, Eng Sing, Riboli, Elio, Elliott, Paul, Tan, Geak Poh, Chotirmall, Sanjay H, Wickremasinghe, Ananda R, Kooner, Jaspal S, Khawaja, Khadija I, Katulanda, Prasad, Mridha, Malay K, Jha, Sujeet, Ranjit Mohan, Anjana, Pradeepa, Guha, Kasturiratne, Anuradhani, Chambers, John C
Published in The European respiratory journal (01.12.2022)
Published in The European respiratory journal (01.12.2022)
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