Human organoids: model systems for human biology and medicine
Kim, Jihoon, Koo, Bon-Kyoung, Knoblich, Juergen A.
Published in Nature reviews. Molecular cell biology (01.10.2020)
Published in Nature reviews. Molecular cell biology (01.10.2020)
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Journal Article
Genetic engineering in organoids
Teriyapirom, Isaree, Batista-Rocha, Andreia S., Koo, Bon-Kyoung
Published in Journal of molecular medicine (Berlin, Germany) (01.04.2021)
Published in Journal of molecular medicine (Berlin, Germany) (01.04.2021)
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Journal Article
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers
Muñoz, Javier, Stange, Daniel E, Schepers, Arnout G, van de Wetering, Marc, Koo, Bon-Kyoung, Itzkovitz, Shalev, Volckmann, Richard, Kung, Kevin S, Koster, Jan, Radulescu, Sorina, Myant, Kevin, Versteeg, Rogier, Sansom, Owen J, van Es, Johan H, Barker, Nick, van Oudenaarden, Alexander, Mohammed, Shabaz, Heck, Albert J R, Clevers, Hans
Published in The EMBO journal (18.07.2012)
Published in The EMBO journal (18.07.2012)
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Stem Cells in Repair of Gastrointestinal Epithelia
Andersson-Rolf, Amanda, Zilbauer, Matthias, Koo, Bon-Kyoung, Clevers, Hans
Published in Physiology (Bethesda, Md.) (01.07.2017)
Published in Physiology (Bethesda, Md.) (01.07.2017)
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Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
Broutier, Laura, Mastrogiovanni, Gianmarco, Verstegen, Monique MA, Francies, Hayley E, Gavarró, Lena Morrill, Bradshaw, Charles R, Allen, George E, Arnes-Benito, Robert, Sidorova, Olga, Gaspersz, Marcia P, Georgakopoulos, Nikitas, Koo, Bon-Kyoung, Dietmann, Sabine, Davies, Susan E, Praseedom, Raaj K, Lieshout, Ruby, IJzermans, Jan N M, Wigmore, Stephen J, Saeb-Parsy, Kourosh, Garnett, Mathew J, van der Laan, Luc JW, Huch, Meritxell
Published in Nature Medicine (01.12.2017)
Published in Nature Medicine (01.12.2017)
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Magazine Article
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
Schwank, Gerald, Koo, Bon-Kyoung, Sasselli, Valentina, Dekkers, Johanna F., Heo, Inha, Demircan, Turan, Sasaki, Nobuo, Boymans, Sander, Cuppen, Edwin, van der Ent, Cornelis K., Nieuwenhuis, Edward E.S., Beekman, Jeffrey M., Clevers, Hans
Published in Cell stem cell (05.12.2013)
Published in Cell stem cell (05.12.2013)
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RNF43 truncations trap CK1 to drive niche‐independent self‐renewal in cancer
Spit, Maureen, Fenderico, Nicola, Jordens, Ingrid, Radaszkiewicz, Tomasz, Lindeboom, Rik GH, Bugter, Jeroen M, Cristobal, Alba, Ootes, Lars, van Osch, Max, Janssen, Eline, Boonekamp, Kim E, Hanakova, Katerina, Potesil, David, Zdrahal, Zbynek, Boj, Sylvia F, Medema, Jan Paul, Bryja, Vitezslav, Koo, Bon‐Kyoung, Vermeulen, Michiel, Maurice, Madelon M
Published in The EMBO journal (15.09.2020)
Published in The EMBO journal (15.09.2020)
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A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis
Tsukiyama, Tadasuke, Zou, Juqi, Kim, Jihoon, Ogamino, Shohei, Shino, Yuki, Masuda, Takamasa, Merenda, Alessandra, Matsumoto, Masaki, Fujioka, Yoichiro, Hirose, Tomonori, Terai, Sayuri, Takahashi, Hidehisa, Ishitani, Tohru, Nakayama, Keiichi I., Ohba, Yusuke, Koo, Bon-Kyoung, Hatakeyama, Shigetsugu
Published in Nature communications (15.09.2020)
Published in Nature communications (15.09.2020)
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Journal Article
DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development
Kraiczy, Judith, Nayak, Komal M, Howell, Kate J, Ross, Alexander, Forbester, Jessica, Salvestrini, Camilla, Mustata, Roxana, Perkins, Sally, Andersson-Rolf, Amanda, Leenen, Esther, Liebert, Anke, Vallier, Ludovic, Rosenstiel, Philip C, Stegle, Oliver, Dougan, Gordon, Heuschkel, Robert, Koo, Bon-Kyoung, Zilbauer, Matthias
Published in Gut (01.01.2019)
Published in Gut (01.01.2019)
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Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration
Choi, Jinwook, Jang, Yu Jin, Dabrowska, Catherine, Iich, Elhadi, Evans, Kelly V., Hall, Helen, Janes, Sam M., Simons, Benjamin D., Koo, Bon-Kyoung, Kim, Jonghwan, Lee, Joo-Hyeon
Published in Nature cell biology (01.09.2021)
Published in Nature cell biology (01.09.2021)
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Journal Article
Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts
Schuijers, Jurian, Junker, Jan Philipp, Mokry, Michal, Hatzis, Pantelis, Koo, Bon-Kyoung, Sasselli, Valentina, van der Flier, Laurens G., Cuppen, Edwin, van Oudenaarden, Alexander, Clevers, Hans
Published in Cell stem cell (05.02.2015)
Published in Cell stem cell (05.02.2015)
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