High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans
de Cássia Lemos Lima, Rita, T Kongstad, Kenneth, Kato, Lucília, José das Silva, Marcos, Franzyk, Henrik, Staerk, Dan
Published in Molecules (Basel, Switzerland) (17.07.2018)
Published in Molecules (Basel, Switzerland) (17.07.2018)
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Coupling Microplate-Based Antibacterial Assay with Liquid Chromatography for High-Resolution Growth Inhibition Profiling of Crude Extracts: Validation and Proof-of-Concept Study with Staphylococcus aureus
Ardalani, Hamidreza, Anam, Syariful, Kromphardt, Kresten J K, Staerk, Dan, Kongstad, Kenneth T
Published in Molecules (Basel, Switzerland) (11.03.2021)
Published in Molecules (Basel, Switzerland) (11.03.2021)
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Structure Elucidation of Prenyl- and Geranyl-Substituted Coumarins in Gerbera piloselloides by NMR Spectroscopy, Electronic Circular Dichroism Calculations, and Single Crystal X-ray Crystallography
Li, Tuo, Ma, Xue, Fedotov, Daniil, Kjaerulff, Louise, Frydenvang, Karla, Coriani, Sonia, Hansen, Paul Robert, Kongstad, Kenneth T, Staerk, Dan
Published in Molecules (Basel, Switzerland) (08.04.2020)
Published in Molecules (Basel, Switzerland) (08.04.2020)
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Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa
Kannangara, Rubini, Siukstaite, Lina, Borch-Jensen, Jonas, Madsen, Bjørn, Kongstad, Kenneth T, Staerk, Dan, Bennedsen, Mads, Okkels, Finn T, Rasmussen, Silas A, Larsen, Thomas O, Frandsen, Rasmus J N, Møller, Birger Lindberg
Published in Nature communications (07.12.2017)
Published in Nature communications (07.12.2017)
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Advancing HPLC-PDA-HRMS-SPE-NMR Analysis of Coumarins in Coleonema album by Use of Orthogonal Reversed-Phase C18 and Pentafluorophenyl Separations
Lima, Rita de Cássia L, Gramsbergen, Simone M, Van Staden, Johannes, Jäger, Anna K, Kongstad, Kenneth T, Staerk, Dan
Published in Journal of natural products (Washington, D.C.) (28.04.2017)
Published in Journal of natural products (Washington, D.C.) (28.04.2017)
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Characterization of Antileishmanial Compounds from Lawsonia inermis L. Leaves Using Semi-High Resolution Antileishmanial Profiling Combined with HPLC-HRMS-SPE-NMR
Iqbal, Kashif, Iqbal, Javeid, Staerk, Dan, Kongstad, Kenneth T
Published in Frontiers in pharmacology (31.05.2017)
Published in Frontiers in pharmacology (31.05.2017)
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Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin
Eghorn, Laura F., Hoestgaard-Jensen, Kirsten, Kongstad, Kenneth T., Bay, Tina, Higgins, David, Frølund, Bente, Wellendorph, Petrine
Published in European journal of pharmacology (05.10.2014)
Published in European journal of pharmacology (05.10.2014)
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Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Eremophila galeata Chinnock
Petersen, Malene J, Lund, Xamuel L, Semple, Susan J, Buirchell, Bevan, Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth T, Stenvang, Jan, Staerk, Dan
Published in Biomolecules (Basel, Switzerland) (18.10.2021)
Published in Biomolecules (Basel, Switzerland) (18.10.2021)
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On the biosynthetic origin of carminic acid
Rasmussen, Silas A., Kongstad, Kenneth T., Khorsand-Jamal, Paiman, Kannangara, Rubini Maya, Nafisi, Majse, Van Dam, Alex, Bennedsen, Mads, Madsen, Bjørn, Okkels, Finn, Gotfredsen, Charlotte H., Staerk, Dan, Thrane, Ulf, Mortensen, Uffe H., Larsen, Thomas O., Frandsen, Rasmus J.N.
Published in Insect biochemistry and molecular biology (01.05.2018)
Published in Insect biochemistry and molecular biology (01.05.2018)
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Identification of α‑Glucosidase Inhibitors in Machilus litseifolia by Combined Use of High-Resolution α‑Glucosidase Inhibition Profiling and HPLC-PDA-HRMS-SPE-NMR
Li, Tuo, Kongstad, Kenneth T, Staerk, Dan
Published in Journal of natural products (Washington, D.C.) (22.02.2019)
Published in Journal of natural products (Washington, D.C.) (22.02.2019)
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Dual High-Resolution α‑Glucosidase and PTP1B Inhibition Profiling Combined with HPLC-PDA-HRMS-SPE-NMR Analysis for the Identification of Potentially Antidiabetic Chromene Meroterpenoids from Rhododendron capitatum
Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth T, Staerk, Dan
Published in Journal of natural products (Washington, D.C.) (24.09.2021)
Published in Journal of natural products (Washington, D.C.) (24.09.2021)
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Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC–HRMS–SPE–NMR
Liu, Bingrui, Kongstad, Kenneth T., Wiese, Stefanie, Jäger, Anna K., Staerk, Dan
Published in Food chemistry (15.07.2016)
Published in Food chemistry (15.07.2016)
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2(5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity
Zhao, Yong, Kjaerulff, Louise, Kongstad, Kenneth T., Heskes, Allison M., Møller, Birger Lindberg, Staerk, Dan
Published in Phytochemistry (Oxford) (01.10.2019)
Published in Phytochemistry (Oxford) (01.10.2019)
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High-Resolution α‑Amylase Assay Combined with High-Performance Liquid Chromatography–Solid-Phase Extraction–Nuclear Magnetic Resonance Spectroscopy for Expedited Identification of α‑Amylase Inhibitors: Proof of Concept and α‑Amylase Inhibitor in Cinnamon
Okutan, Leyla, Kongstad, Kenneth T, Jäger, Anna K, Staerk, Dan
Published in Journal of agricultural and food chemistry (26.11.2014)
Published in Journal of agricultural and food chemistry (26.11.2014)
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Polypharmacology-Labeled Molecular Networking: An Analytical Technology Workflow for Accelerated Identification of Multiple Bioactive Constituents in Complex Extracts
Zhao, Yong, Gericke, Oliver, Li, Tuo, Kjaerulff, Louise, Kongstad, Kenneth T., Heskes, Allison Maree, Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, Henrietta, Coriani, Sonia, Semple, Susan J., Staerk, Dan
Published in Analytical chemistry (Washington) (07.03.2023)
Published in Analytical chemistry (Washington) (07.03.2023)
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Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic triterpenoids and phloroglucinol derivatives
Liang, Chao, Staerk, Dan, Kongstad, Kenneth T.
Published in Journal of functional foods (01.01.2020)
Published in Journal of functional foods (01.01.2020)
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Combined magnetic ligand fishing and high-resolution inhibition profiling for identification of α-glucosidase inhibitory ligands: A new screening approach based on complementary inhibition and affinity profiles
Wubshet, Sileshi G., Liu, Bingrui, Kongstad, Kenneth T., Böcker, Ulrike, Petersen, Malene J., Li, Tuo, Wang, Junru, Staerk, Dan
Published in Talanta (Oxford) (01.08.2019)
Published in Talanta (Oxford) (01.08.2019)
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Identification of PTP1B and α‑Glucosidase Inhibitory Serrulatanes from Eremophila spp. by Combined use of Dual High-Resolution PTP1B and α‑Glucosidase Inhibition Profiling and HPLC-HRMS-SPE-NMR
Wubshet, Sileshi G, Tahtah, Yousof, Heskes, Allison M, Kongstad, Kenneth T, Pateraki, Irini, Hamberger, Björn, Møller, Birger L, Staerk, Dan
Published in Journal of natural products (Washington, D.C.) (22.04.2016)
Published in Journal of natural products (Washington, D.C.) (22.04.2016)
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4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric γ-aminobutyric acid receptor binding site
Giraudo, Alessandro, Krall, Jacob, Nielsen, Birgitte, Sørensen, Troels E., Kongstad, Kenneth T., Rolando, Barbara, Boschi, Donatella, Frølund, Bente, Lolli, Marco L.
Published in European journal of medicinal chemistry (05.10.2018)
Published in European journal of medicinal chemistry (05.10.2018)
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