A Facile and Efficient Synthesis of 3,3-Dimethyl Isopropylidene Proline From (+)-3-Carene
Nair, Latha G, Saksena, Anil, Lovey, Raymond, Sannigrahi, Mousumi, Wong, Jesse, Kong, Jianshe, Fu, Xiaoyong, Girijavallabhan, Viyyoor
Published in Journal of organic chemistry (19.02.2010)
Published in Journal of organic chemistry (19.02.2010)
Get full text
Journal Article
Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor
Arasappan, Ashok, Bennett, Frank, Bogen, Stephane L, Venkatraman, Srikanth, Blackman, Melissa, Chen, Kevin X, Hendrata, Siska, Huang, Yuhua, Huelgas, Regina M, Nair, Latha, Padilla, Angela I, Pan, Weidong, Pike, Russell, Pinto, Patrick, Ruan, Sumei, Sannigrahi, Mousumi, Velazquez, Francisco, Vibulbhan, Bancha, Wu, Wanli, Yang, Weiying, Saksena, Anil K, Girijavallabhan, Viyyoor, Shih, Neng-Yang, Kong, Jianshe, Meng, Tao, Jin, Yan, Wong, Jesse, McNamara, Paul, Prongay, Andrew, Madison, Vincent, Piwinski, John J, Cheng, Kuo-Chi, Morrison, Richard, Malcolm, Bruce, Tong, Xiao, Ralston, Robert, Njoroge, F. George
Published in ACS medicinal chemistry letters (13.05.2010)
Published in ACS medicinal chemistry letters (13.05.2010)
Get full text
Journal Article
Discovery of a vorapaxar analog with increased aqueous solubility
Xia, Yan, Chackalamannil, Samuel, Greenlee, William J., Wang, Yuguang, Hu, Zhiyong, Root, Yuriko, Wong, Jesse, Kong, Jianshe, Ahn, Ho-Sam, Boykow, George, Hsieh, Yunsheng, Kurowski, Stan, Chintala, Madhu
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Get full text
Journal Article
One-Step Synthesis and Isolation of N-(tert-Butoxycarbonyl)-N′-methylthiourea on a Large Scale
Andreani, Teresa, Jin, Yan, Kong, Jianshe, Liang, Xian, Meng, Tao, Wong, Jesse K.
Published in Synthetic communications (22.10.2008)
Published in Synthetic communications (22.10.2008)
Get full text
Journal Article
Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRASG12C Inhibitor ARS-2102
Yang, Xiaogen, Li, Zhiwen, Xu, Wenwen, Zhu, Guanming, Feng, Xiantong, Zhang, Jun, Zhao, Hongbin, Chen, Yuyin, Kong, Jianshe, Mai, Wanping, Li, Lian-Sheng, Pippel, Daniel J., Ren, Pingda, Deng, Xiaohu
Published in Organic process research & development (20.01.2023)
Published in Organic process research & development (20.01.2023)
Get full text
Journal Article
Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRAS G12C Inhibitor ARS-2102
Yang, Xiaogen, Li, Zhiwen, Xu, Wenwen, Zhu, Guanming, Feng, Xiantong, Zhang, Jun, Zhao, Hongbin, Chen, Yuyin, Kong, Jianshe, Mai, Wanping, Li, Lian-Sheng, Pippel, Daniel J., Ren, Pingda, Deng, Xiaohu
Published in Organic process research & development (20.01.2023)
Published in Organic process research & development (20.01.2023)
Get full text
Journal Article
Regioselective Functionalization of 4‑Methyl‑1H‑indole for Scalable Synthesis of 2‑Cyano-5-formyl-4-methyl‑1H‑indole
Zhang, Jun, Hu, Yun, Wang, Haiyu, Guo, Aixin, Kong, Jianshe, Ma, Rujian, Wu, Tao, Wang, Yi, Li, Lian-Sheng, Mai, Wanping, Ren, Pingda, Deng, Xiaohu
Published in Organic process research & development (19.01.2018)
Published in Organic process research & development (19.01.2018)
Get full text
Journal Article
Regioselective Functionalization of 4-Methyl-1 H -indole for Scalable Synthesis of 2-Cyano-5-formyl-4-methyl-1 H -indole
Zhang, Jun, Hu, Yun, Wang, Haiyu, Guo, Aixin, Kong, Jianshe, Ma, Rujian, Wu, Tao, Wang, Yi, Li, Lian-Sheng, Mai, Wanping, Ren, Pingda, Deng, Xiaohu
Published in Organic process research & development (19.01.2018)
Published in Organic process research & development (19.01.2018)
Get full text
Journal Article
Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection
Venkatraman, Srikanth, Bogen, Stéphane L, Arasappan, Ashok, Bennett, Frank, Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond, Hendrata, Siska, Huang, Yuhua, Pan, Weidong, Parekh, Tejal, Pinto, Patrick, Popov, Veljko, Pike, Russel, Ruan, Sumei, Santhanam, Bama, Vibulbhan, Bancha, Wu, Wanli, Yang, Weiying, Kong, Jianshe, Liang, Xiang, Wong, Jesse, Liu, Rong, Butkiewicz, Nancy, Chase, Robert, Hart, Andrea, Agrawal, Sony, Ingravallo, Paul, Pichardo, John, Kong, Rong, Baroudy, Bahige, Malcolm, Bruce, Guo, Zhuyan, Prongay, Andrew, Madison, Vincent, Broske, Lisa, Cui, Xiaoming, Cheng, Kuo-Chi, Hsieh, Yunsheng, Brisson, Jean-Marc, Prelusky, Danial, Korfmacher, Walter, White, Ronald, Bogdanowich-Knipp, Susan, Pavlovsky, Anastasia, Bradley, Prudence, Saksena, Anil K, Ganguly, Ashit, Piwinski, John, Girijavallabhan, Viyyoor, Njoroge, F. George
Published in Journal of medicinal chemistry (05.10.2006)
Published in Journal of medicinal chemistry (05.10.2006)
Get full text
Journal Article
PDE9 억제제의 제조 방법 및 사용 방법
SVENSTRUP NIELS, SUN FENGLAI, SUN JINXU, ZHANG JUN, ZHU JINGYANG, MA RUJIAN, SUN JIKUI, KONG JIANSHE, ZHANG JUNHUA, MENG XIAO, CHEN YUYIN, QIN LIANG, XIAO HUANMING
Year of Publication 17.02.2020
Get full text
Year of Publication 17.02.2020
Patent
Syntheses of Potential Degradation Products of Phenylephrine in OTC Products
Chan, T.-M., Kong, Jianshe, McNamara, Paul, Wong, Jesse K.
Published in Synthetic communications (20.06.2008)
Published in Synthetic communications (20.06.2008)
Get full text
Journal Article
Process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-(tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one
Ma, Rujian, Kong, Jianshe, Sun, Fenglai, Zhu, Jingyang, Sun, Jinxu, Zhang, Jun, Qin, Liang, Sun, Jikui, Zhang, Junhua, Meng, Xiao, Svenstrup, Niels, Chen, Yuyin, Xiao, Huanming
Year of Publication 04.06.2024
Get full text
Year of Publication 04.06.2024
Patent
METHODS OF MAKING AND USING PDE9 INHIBITORS
XIAO, Huanming, SUN, Jinxu, SUN, Jikui, KONG, Jianshe, MENG, Xiao, SUN, Fenglai, ZHU, Jingyang, ZHANG, Jun, CHEN, Yuyin, QIN, Liang, SVENSTRUP, Niels, ZHANG, Junhua, MA, Rujian
Year of Publication 31.01.2024
Get full text
Year of Publication 31.01.2024
Patent
METHODS OF MAKING AND USING PDE9 INHIBITORS
XIAO, Huanming, SUN, Jinxu, SUN, Jikui, KONG, Jianshe, MENG, Xiao, SUN, Fenglai, ZHU, Jingyang, ZHANG, Jun, CHEN, Yuyin, QIN, Liang, SVENSTRUP, Niels, ZHANG, Junhua, MA, Rujian
Year of Publication 01.11.2023
Get full text
Year of Publication 01.11.2023
Patent
METHODS OF MAKING AND USING PDE9 INHIBITORS
XIAO, Huanming, SUN, Jinxu, SUN, Jikui, KONG, Jianshe, MENG, Xiao, SUN, Fenglai, ZHU, Jingyang, ZHANG, Jun, CHEN, Yuyin, QIN, Liang, SVENSTRUP, Niels, ZHANG, Junhua, MA, Rujian
Year of Publication 15.06.2023
Get full text
Year of Publication 15.06.2023
Patent