CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
De Rubeis, Silvia, Pasciuto, Emanuela, Li, Ka Wan, Fernández, Esperanza, Di Marino, Daniele, Buzzi, Andrea, Ostroff, Linnaea E., Klann, Eric, Zwartkruis, Fried J.T., Komiyama, Noboru H., Grant, Seth G.N., Poujol, Christel, Choquet, Daniel, Achsel, Tilmann, Posthuma, Danielle, Smit, August B., Bagni, Claudia
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Published in Neuron (Cambridge, Mass.) (18.09.2013)
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The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults
Martel, Marc-André, Ryan, Tomás J., Bell, Karen F.S., Fowler, Jill H., McMahon, Aoife, Al-Mubarak, Bashayer, Komiyama, Noboru H., Horsburgh, Karen, Kind, Peter C., Grant, Seth G.N., Wyllie, David J.A., Hardingham, Giles E.
Published in Neuron (Cambridge, Mass.) (10.05.2012)
Published in Neuron (Cambridge, Mass.) (10.05.2012)
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Developmental disruption and restoration of brain synaptome architecture in the murine Pax6 neurodevelopmental disease model
Tomas-Roca, Laura, Qiu, Zhen, Fransén, Erik, Gokhale, Ragini, Bulovaite, Edita, Price, David J, Komiyama, Noboru H, Grant, Seth G N
Published in Nature communications (11.11.2022)
Published in Nature communications (11.11.2022)
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PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits
Broadhead, Matthew J, Horrocks, Mathew H, Zhu, Fei, Muresan, Leila, Benavides-Piccione, Ruth, DeFelipe, Javier, Fricker, David, Kopanitsa, Maksym V, Duncan, Rory R, Klenerman, David, Komiyama, Noboru H, Lee, Steven F, Grant, Seth G N
Published in Scientific reports (25.04.2016)
Published in Scientific reports (25.04.2016)
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Synaptic scaffold evolution generated components of vertebrate cognitive complexity
Nithianantharajah, Jess, Komiyama, Noboru H, McKechanie, Andrew, Johnstone, Mandy, Blackwood, Douglas H, St Clair, David, Emes, Richard D, van de Lagemaat, Louie N, Saksida, Lisa M, Bussey, Timothy J, Grant, Seth G N
Published in Nature neuroscience (01.01.2013)
Published in Nature neuroscience (01.01.2013)
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De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
KIROV, G, POCKLINGTON, A. J, GROZEVA, D, FJODOROVA, M, WOLLERTON, R, REES, E, NIKOLOV, I, VAN DE LAGEMAAT, L. N, BAYES, A, FERNANDEZ, E, OLASON, P. I, BÖTTCHER, Y, HOLMANS, P, KOMIYAMA, N. H, COLLINS, M. O, CHOUDHARY, J, STEFANSSON, K, STEFANSSON, H, GRANT, Sgn, PURCELL, S, SKLAR, P, O'DONOVAN, M. C, OWEN, M. J, IVANOV, D, IKEDA, M, RUDERFER, D, MORAN, J, CHAMBERT, K, TONCHEVA, D, GEORGIEVA, L
Published in Molecular psychiatry (01.02.2012)
Published in Molecular psychiatry (01.02.2012)
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Architecture of the Mouse Brain Synaptome
Zhu, Fei, Cizeron, Mélissa, Qiu, Zhen, Benavides-Piccione, Ruth, Kopanitsa, Maksym V., Skene, Nathan G., Koniaris, Babis, DeFelipe, Javier, Fransén, Erik, Komiyama, Noboru H., Grant, Seth G.N.
Published in Neuron (Cambridge, Mass.) (22.08.2018)
Published in Neuron (Cambridge, Mass.) (22.08.2018)
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A polygenic burden of rare disruptive mutations in schizophrenia
Purcell, Shaun M, Moran, Jennifer L, Fromer, Menachem, Ruderfer, Douglas, Solovieff, Nadia, Roussos, Panos, O'Dushlaine, Colm, Chambert, Kimberly, Bergen, Sarah E, Kähler, Anna, Duncan, Laramie, Stahl, Eli, Genovese, Giulio, Fernández, Esperanza, Collins, Mark O, Komiyama, Noboru H, Choudhary, Jyoti S, Magnusson, Patrik K E, Banks, Eric, Shakir, Khalid, Garimella, Kiran, Fennell, Tim, DePristo, Mark, Grant, Seth G N, Haggarty, Stephen J, Gabriel, Stacey, Scolnick, Edward M, Lander, Eric S, Hultman, Christina M, Sullivan, Patrick F, McCarroll, Steven A, Sklar, Pamela
Published in Nature (London) (13.02.2014)
Published in Nature (London) (13.02.2014)
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Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence
Fernández, Esperanza, Collins, Mark O., Frank, René A.W., Zhu, Fei, Kopanitsa, Maksym V., Nithianantharajah, Jess, Lemprière, Sarah A., Fricker, David, Elsegood, Kathryn A., McLaughlin, Catherine L., Croning, Mike D.R., Mclean, Colin, Armstrong, J. Douglas, Hill, W. David, Deary, Ian J., Cencelli, Giulia, Bagni, Claudia, Fromer, Menachem, Purcell, Shaun M., Pocklington, Andrew J., Choudhary, Jyoti S., Komiyama, Noboru H., Grant, Seth G.N.
Published in Cell reports (Cambridge) (17.10.2017)
Published in Cell reports (Cambridge) (17.10.2017)
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Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior
Ryan, Tomás J, Kopanitsa, Maksym V, Indersmitten, Tim, Nithianantharajah, Jess, Afinowi, Nurudeen O, Pettit, Charles, Stanford, Lianne E, Sprengel, Rolf, Saksida, Lisa M, Bussey, Timothy J, O'Dell, Thomas J, Grant, Seth G N, Komiyama, Noboru H
Published in Nature neuroscience (01.01.2013)
Published in Nature neuroscience (01.01.2013)
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Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins
Uren, Rachel T, Croning, Mike D R, Fernández, Esperanza, Armstrong, J Douglas, Kopanitsa, Maksym V, Choudhary, Jyoti S, Collins, Mark O, Zografos, Lysimachos, Grant, Seth G N, Komiyama, Noboru H
Published in Molecular systems biology (2009)
Published in Molecular systems biology (2009)
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Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1
McQueen, Jamie, Ryan, Tomás J, McKay, Sean, Marwick, Katie, Baxter, Paul, Carpanini, Sarah M, Wishart, Thomas M, Gillingwater, Thomas H, Manson, Jean C, Wyllie, David J A, Grant, Seth G N, McColl, Barry W, Komiyama, Noboru H, Hardingham, Giles E
Published in eLife (21.07.2017)
Published in eLife (21.07.2017)
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The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences
McKay, Sean, Ryan, Tomás J., McQueen, Jamie, Indersmitten, Tim, Marwick, Katie F.M., Hasel, Philip, Kopanitsa, Maksym V., Baxter, Paul S., Martel, Marc-André, Kind, Peter C., Wyllie, David J.A., O’Dell, Thomas J., Grant, Seth G.N., Hardingham, Giles E., Komiyama, Noboru H.
Published in Cell reports (Cambridge) (23.10.2018)
Published in Cell reports (Cambridge) (23.10.2018)
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TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function
Coba, Marcelo P, Komiyama, Noboru H, Nithianantharajah, Jess, Kopanitsa, Maksym V, Indersmitten, Tim, Skene, Nathan G, Tuck, Ellie J, Fricker, David G, Elsegood, Kathryn A, Stanford, Lianne E, Afinowi, Nurudeen O, Saksida, Lisa M, Bussey, Timothy J, O'Dell, Thomas J, Grant, Seth G N
Published in The Journal of neuroscience (03.10.2012)
Published in The Journal of neuroscience (03.10.2012)
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Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression
McLean, Gordon W, Komiyama, Noboru H, Serrels, Bryan, Asano, Hidefumi, Reynolds, Louise, Conti, Francesco, Hodivala-Dilke, Kairbaan, Metzger, Daniel, Chambon, Pierre, Grant, Seth G N, Frame, Margaret C
Published in Genes & development (15.12.2004)
Published in Genes & development (15.12.2004)
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