The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis
Moriwaki, Kenta, Park, Christa, Koyama, Kazuha, Balaji, Sakthi, Kita, Kohei, Yagi, Ryoko, Komazawa-Sakon, Sachiko, Semba, Manami, Asuka, Tatsuya, Nakano, Hiroyasu, Kamada, Yoshihiro, Miyoshi, Eiji, Chan, Francis K M
Published in Mucosal immunology (01.01.2022)
Published in Mucosal immunology (01.01.2022)
Get full text
Journal Article
Crucial role for autophagy in degranulation of mast cells
Ushio, Hiroko, PhD, Ueno, Takashi, PhD, Kojima, Yuko, PhD, Komatsu, Masaaki, PhD, Tanaka, Satoshi, PhD, Yamamoto, Akitsugu, PhD, Ichimura, Yoshinobu, PhD, Ezaki, Junji, PhD, Nishida, Keigo, PhD, Komazawa-Sakon, Sachiko, BD, Niyonsaba, François, PhD, Ishii, Tetsuro, PhD, Yanagawa, Toru, DDS, MD, PhD, Kominami, Eiki, MD, PhD, Ogawa, Hideoki, MD, PhD, Okumura, Ko, MD, PhD, Nakano, Hiroyasu, MD, PhD
Published in Journal of allergy and clinical immunology (01.05.2011)
Published in Journal of allergy and clinical immunology (01.05.2011)
Get full text
Journal Article
Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum
Piao, Xuehua, Yamazaki, Soh, Komazawa‐Sakon, Sachiko, Miyake, Sanae, Nakabayashi, Osamu, Kurosawa, Takeyuki, Mikami, Tetsuo, Tanaka, Minoru, Van Rooijen, Nico, Ohmuraya, Masaki, Oikawa, Akira, Kojima, Yuko, Kakuta, Soichiro, Uchiyama, Yasuo, Tanaka, Masato, Nakano, Hiroyasu
Published in Hepatology (Baltimore, Md.) (01.01.2017)
Published in Hepatology (Baltimore, Md.) (01.01.2017)
Get full text
Journal Article
MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL
Nakabayashi, Osamu, Takahashi, Hirotaka, Moriwaki, Kenta, Komazawa-Sakon, Sachiko, Ohtake, Fumiaki, Murai, Shin, Tsuchiya, Yuichi, Koyahara, Yuki, Saeki, Yasushi, Yoshida, Yukiko, Yamazaki, Soh, Tokunaga, Fuminori, Sawasaki, Tatsuya, Nakano, Hiroyasu
Published in Communications biology (19.01.2021)
Published in Communications biology (19.01.2021)
Get full text
Journal Article
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway
Nakajima, Akihito, Komazawa-Sakon, Sachiko, Takekawa, Mutsuhiro, Sasazuki, Tomonari, Yeh, Wen-Chen, Yagita, Hideo, Okumura, Ko, Nakano, Hiroyasu
Published in The EMBO journal (29.11.2006)
Published in The EMBO journal (29.11.2006)
Get full text
Journal Article
Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis
Tsuchiya, Yuichi, Seki, Takao, Kobayashi, Kenta, Komazawa-Sakon, Sachiko, Shichino, Shigeyuki, Nishina, Takashi, Fukuhara, Kyoko, Ikejima, Kenichi, Nagai, Hidenari, Igarashi, Yoshinori, Ueha, Satoshi, Oikawa, Akira, Tsurusaki, Shinya, Yamazaki, Soh, Nishiyama, Chiharu, Mikami, Tetuo, Yagita, Hideo, Okumura, Ko, Kido, Taketomo, Miyajima, Atsushi, Matsushima, Kouji, Imasaka, Mai, Araki, Kimi, Imamura, Toru, Ohmuraya, Masaki, Tanaka, Minoru, Nakano, Hiroyasu
Published in Nature communications (09.10.2023)
Published in Nature communications (09.10.2023)
Get full text
Journal Article
Proscillaridin A Sensitizes Human Colon Cancer Cells to TRAIL-Induced Cell Death
Semba, Manami, Takamatsu, Shinji, Komazawa-Sakon, Sachiko, Miyoshi, Eiji, Nishiyama, Chiharu, Nakano, Hiroyasu, Moriwaki, Kenta
Published in International journal of molecular sciences (23.06.2022)
Published in International journal of molecular sciences (23.06.2022)
Get full text
Journal Article
Lewis glycosphingolipids as critical determinants of TRAIL sensitivity in cancer cells
Fukuoka, Tomoya, Moriwaki, Kenta, Takamatsu, Shinji, Kondo, Jumpei, Tanaka-Okamoto, Miki, Tomioka, Azusa, Semba, Manami, Komazawa-Sakon, Sachiko, Kamada, Yoshihiro, Kaji, Hiroyuki, Miyamoto, Yasuhide, Inoue, Masahiro, Bessho, Kazuhiko, Miyoshi, Yoko, Ozono, Keiichi, Nakano, Hiroyasu, Miyoshi, Eiji
Published in Oncogene (16.09.2022)
Published in Oncogene (16.09.2022)
Get full text
Journal Article
Cellular FLICE-Inhibitory Protein Regulates Tissue Homeostasis
Nakano, Hiroyasu, Piao, Xuehua, Shindo, Ryodai, Komazawa-Sakon, Sachiko
Published in Apoptotic and Non-Apoptotic Cell Death (01.01.2017)
Published in Apoptotic and Non-Apoptotic Cell Death (01.01.2017)
Get full text
Book Chapter
Journal Article
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis
Piao, Xuehua, Komazawa-Sakon, Sachiko, Nishina, Takashi, Koike, Masato, Piao, Jiang-Hu, Ehlken, Hanno, Kurihara, Hidetake, Hara, Mutsuko, Van Rooijen, Nico, Schütz, Günther, Ohmuraya, Masaki, Uchiyama, Yasuo, Yagita, Hideo, Okumura, Ko, He, You-Wen, Nakano, Hiroyasu
Published in Science signaling (18.12.2012)
Published in Science signaling (18.12.2012)
Get more information
Journal Article
Interleukin-11 links oxidative stress and compensatory proliferation
Nishina, Takashi, Komazawa-Sakon, Sachiko, Yanaka, Saeko, Piao, Xuehua, Zheng, Dong-Mei, Piao, Jiang-Hu, Kojima, Yuko, Yamashina, Shunhei, Sano, Emiko, Putoczki, Tracy, Doi, Takahiro, Ueno, Takashi, Ezaki, Junji, Ushio, Hiroko, Ernst, Matthias, Tsumoto, Kouhei, Okumura, Ko, Nakano, Hiroyasu
Published in Science signaling (17.01.2012)
Published in Science signaling (17.01.2012)
Get more information
Journal Article
Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis
Murai, Shin, Takakura, Kanako, Sumiyama, Kenta, Moriwaki, Kenta, Terai, Kenta, Komazawa-Sakon, Sachiko, Seki, Takao, Yamaguchi, Yoshifumi, Mikami, Tetuo, Araki, Kimi, Ohmuraya, Masaki, Matsuda, Michiyuki, Nakano, Hiroyasu
Published in Communications biology (05.12.2022)
Published in Communications biology (05.12.2022)
Get full text
Journal Article
Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome
Sakata, Kazuya, Araki, Kimi, Nakano, Hiroyasu, Nishina, Takashi, Komazawa-Sakon, Sachiko, Murai, Shin, Lee, Grace E, Hashimoto, Daisuke, Suzuki, Chigure, Uchiyama, Yasuo, Notohara, Kenji, Gukovskaya, Anna S, Gukovsky, Ilya, Yamamura, Ken-Ichi, Baba, Hideo, Ohmuraya, Masaki
Published in Scientific reports (15.11.2016)
Published in Scientific reports (15.11.2016)
Get full text
Journal Article
Regenerating islet-derived protein (Reg)3β plays a crucial role in attenuation of ileitis and colitis in mice
Shindo, Ryodai, Katagiri, Takaharu, Komazawa-Sakon, Sachiko, Ohmuraya, Masaki, Takeda, Wakami, Nakagawa, Yoshiko, Nakagata, Naomi, Sakuma, Tetsushi, Yamamoto, Takashi, Nishiyama, Chiharu, Nishina, Takashi, Yamazaki, Soh, Kameda, Hideto, Nakano, Hiroyasu
Published in Biochemistry and biophysics reports (01.03.2020)
Published in Biochemistry and biophysics reports (01.03.2020)
Get full text
Journal Article
Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis
Shindo, Ryodai, Ohmuraya, Masaki, Komazawa-Sakon, Sachiko, Miyake, Sanae, Deguchi, Yutaka, Yamazaki, Soh, Nishina, Takashi, Yoshimoto, Takayuki, Kakuta, Soichiro, Koike, Masato, Uchiyama, Yasuo, Konishi, Hiroyuki, Kiyama, Hiroshi, Mikami, Tetuo, Moriwaki, Kenta, Araki, Kimi, Nakano, Hiroyasu
Published in iScience (31.05.2019)
Published in iScience (31.05.2019)
Get full text
Journal Article
Fusion of OTT to BSAC Results in Aberrant Up-regulation of Transcriptional Activity
Sawada, Taisuke, Nishiyama, Chiharu, Kishi, Takuma, Sasazuki, Tomonari, Komazawa-Sakon, Sachiko, Xue, Xin, Piao, Jiang-Hu, Ogata, Hideko, Nakayama, Jun-ichi, Taki, Tomohiko, Hayashi, Yasuhide, Watanabe, Mamoru, Yagita, Hideo, Okumura, Ko, Nakano, Hiroyasu
Published in The Journal of biological chemistry (26.09.2008)
Published in The Journal of biological chemistry (26.09.2008)
Get full text
Journal Article
A high-sensitivity ELISA for detection of human FGF18 in culture supernatants from tumor cell lines
Tsuchiya, Yuichi, Komazawa-Sakon, Sachiko, Tanaka, Masato, Kanokogi, Takumi, Moriwaki, Kenta, Akiba, Hisaya, Yagita, Hideo, Okumura, Ko, Entzminger, Kevin C., Okumura, C.J., Maruyama, Toshiaki, Nakano, Hiroyasu
Published in Biochemical and biophysical research communications (01.10.2023)
Published in Biochemical and biophysical research communications (01.10.2023)
Get full text
Journal Article
Blockade of TNF receptor superfamily 1 (TNFR1)–dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation
Piao, Xuehua, Miura, Ryosuke, Miyake, Sanae, Komazawa-Sakon, Sachiko, Koike, Masato, Shindo, Ryodai, Takeda, Junji, Hasegawa, Akito, Abe, Riichiro, Nishiyama, Chiharu, Mikami, Tetsuo, Yagita, Hideo, Uchiyama, Yasuo, Nakano, Hiroyasu
Published in Journal of allergy and clinical immunology (01.01.2019)
Published in Journal of allergy and clinical immunology (01.01.2019)
Get full text
Journal Article
Tumor Necrosis Factor α (TNFα) Induces the Unfolded Protein Response (UPR) in a Reactive Oxygen Species (ROS)-dependent Fashion, and the UPR Counteracts ROS Accumulation by TNFα
Xue, Xin, Piao, Jiang-Hu, Nakajima, Akihito, Sakon-Komazawa, Sachiko, Kojima, Yuko, Mori, Kazutoshi, Yagita, Hideo, Okumura, Ko, Harding, Heather, Nakano, Hiroyasu
Published in The Journal of biological chemistry (07.10.2005)
Published in The Journal of biological chemistry (07.10.2005)
Get full text
Journal Article
MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIP L
Nakabayashi, Osamu, Takahashi, Hirotaka, Moriwaki, Kenta, Komazawa-Sakon, Sachiko, Ohtake, Fumiaki, Murai, Shin, Tsuchiya, Yuichi, Koyahara, Yuki, Saeki, Yasushi, Yoshida, Yukiko, Yamazaki, Soh, Tokunaga, Fuminori, Sawasaki, Tatsuya, Nakano, Hiroyasu
Published in Communications biology (19.01.2021)
Get full text
Published in Communications biology (19.01.2021)
Journal Article