Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation
Komarova, Elena A, Gudkov, Andrei V, Strom, Evguenia, Sathe, Swati, Komarov, Pavel G, Chernova, Olga B, Pavlovska, Ivanda, Shyshynova, Inna, Bosykh, Dmitry A, Burdelya, Lyudmila G, Macklis, Roger M, Skaliter, Rami
Published in Nature chemical biology (01.09.2006)
Published in Nature chemical biology (01.09.2006)
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Journal Article
Small-Molecule Multidrug Resistance―Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma
BURKHART, Catherine A, WATT, Fujiko, KOMAROV, Pavel G, GUROVA, Katerina V, SARTORELLI, Alan C, MARSHALL, Glenn M, NORRIS, Murray D, GUDKOV, Andrei V, HABER, Michelle, MURRAY, Jayne, PAJIC, Marina, PROKVOLIT, Anatoly, CHENGYUAN XUE, FLEMMING, Claudia, SMITH, Janice, PURMAL, Andrei, ISACHENKO, Nadezhda
Published in Cancer research (Chicago, Ill.) (15.08.2009)
Published in Cancer research (Chicago, Ill.) (15.08.2009)
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Journal Article
p53 is a suppressor of inflammatory response in mice
Komarova, Elena A, Krivokrysenko, Vadim, Wang, Kaihua, Neznanov, Nickolay, Chernov, Mikhail V, Komarov, Pavel G, Brennan, Marie-Luise, Golovkina, Tatiana V, Rokhlin, Oskar W, Kuprash, Dmitry V, Nedospasov, Sergei A, Hazen, Stanley L, Feinstein, Elena, Gudkov, Andrei V
Published in The FASEB journal (01.06.2005)
Published in The FASEB journal (01.06.2005)
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Journal Article
A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice
Leonova, Katerina I., Shneyder, Jelena, Antoch, Marina P., Toshkov, Illia A., Novototskaya, Liliya R., Komarov, Pavel G., Komarova, Elena A., Gudkov, Andrei V.
Published in Cell cycle (Georgetown, Tex.) (01.04.2010)
Published in Cell cycle (Georgetown, Tex.) (01.04.2010)
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Journal Article
Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancer
Narizhneva, Natalia V., Tararova, Natalia D., Ryabokon, Petro, Shyshynova, Inna, Prokvolit, Anatoly, Komarov, Pavel G., Purmal, Andrei A., Gudkov, Andrei V., Gurova, Katerina V.
Published in Cell cycle (Georgetown, Tex.) (15.12.2009)
Published in Cell cycle (Georgetown, Tex.) (15.12.2009)
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Journal Article
OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis
Korotchkina, Lioubov, Kazyulkin, Denis, Komarov, Pavel G., Polinsky, Alex, Andrianova, Ekaterina L., Joshi, Sangeeta, Gupta, Mahima, Vujcic, Slavoljub, Kononov, Eugene, Toshkov, Ilia, Tian, Yuan, Krasnov, Peter, Chernov, Mikhail V., Veith, Jean, Antoch, Marina P., Middlemiss, Shiloh, Somers, Klaartje, Lock, Richard B., Norris, Murray D., Henderson, Michelle J., Haber, Michelle, Chernova, Olga B., Gudkov, Andrei V.
Published in Leukemia (01.07.2020)
Published in Leukemia (01.07.2020)
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Journal Article
Small Molecules That Dramatically Alter Multidrug Resistance Phenotype by Modulating the Substrate Specificity of P-Glycoprotein
Kondratov, Roman V., Komarov, Pavel G., Becker, Yigal, Ewenson, Ariel, Gudkov, Andrei V.
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (20.11.2001)
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Journal Article
A Chemical Inhibitor of p53 that Protects Mice from the Side Effects of Cancer Therapy
Komarov, Pavel G., Komarova, Elena A., Kondratov, Roman V., Christov-Tselkov, Konstantin, Coon, John S., Chernov, Mikhail V., Gudkov, Andrei V.
Published in Science (American Association for the Advancement of Science) (10.09.1999)
Published in Science (American Association for the Advancement of Science) (10.09.1999)
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Journal Article
p53 Involvement in the Control of Murine Hair Follicle Regression
Botchkarev, Vladimir A., Komarova, Elena A., Siebenhaar, Frank, Botchkareva, Natalia V., Sharov, Andrei A., Komarov, Pavel G., Maurer, Marcus, Gudkov, Andrei V., Gilchrest, Barbara A.
Published in The American journal of pathology (01.06.2001)
Published in The American journal of pathology (01.06.2001)
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Journal Article
Small Molecule MRP1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Model of Neuroblastoma
Burkhart, Catherine A., Watt, Fujiko, Murray, Jayne, Pajic, Marina, Prokvolit, Anatoly, Xue, Chengyuan, Flemming, Claudia, Smith, Janice, Purmal, Andrei, Isachenko, Nadezhda, Komarov, Pavel G., Gurova, Katerina V., Sartorelli, Alan C., Marshall, Glenn M., Norris, Murray D., Gudkov, Andrei V., Haber, Michelle
Published in Cancer research (Chicago, Ill.) (04.08.2009)
Published in Cancer research (Chicago, Ill.) (04.08.2009)
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Journal Article
REMOVAL OF SENESCENCE-ASSOCIATED MACROPHAGES
KAZYULKIN, Denis N, POLINSKY, Alexander, BALAN, Vitaly, KOMAROV, Pavel G, HALL, Brandon M, GUDKOV, Andrei, CHERNOVA, Olga
Year of Publication 23.04.2020
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Year of Publication 23.04.2020
Patent
Inhibition of cytarabine‐induced MDR1 (P‐glycoprotein) gene activation in human tumor cells by fatty acid‐polyethylene glycol‐fatty acid diesters, novel inhibitors of P‐glycoprotein function
Komarov, Pavel G., Shtil, Alexander A., Buckingham, Lela E., Balasubramanian, M., Piraner, Olga, Emanuele, R. Martin, Roninson, Igor B., Coon, John S.
Published in International journal of cancer (09.10.1996)
Published in International journal of cancer (09.10.1996)
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Journal Article
Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine
Komarov, P G, Shtil, A A, Holian, O, Tee, L, Buckingham, L, Mechetner, E B, Roninson, I B, Coon, J S
Published in Oncology research (1998)
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Published in Oncology research (1998)
Journal Article
Inhibition of cytarabine-inducedMDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function
Komarov, Pavel G., Shtil, Alexander A., Buckingham, Lela E., Balasubramanian, M., Piraner, Olga, Emanuele, R. Martin, Roninson, Igor B., Coon, John S.
Published in International journal of cancer (09.10.1996)
Published in International journal of cancer (09.10.1996)
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Journal Article