Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension
Weiss, Astrid, Neubauer, Moritz Christian, Yerabolu, Dinesh, Kojonazarov, Baktybek, Schlueter, Beate Christiane, Neubert, Lavinia, Jonigk, Danny, Baal, Nelli, Ruppert, Clemens, Dorfmuller, Peter, Pullamsetti, Soni Savai, Weissmann, Norbert, Ghofrani, Hossein-Ardeschir, Grimminger, Friedrich, Seeger, Werner, Schermuly, Ralph Theo
Published in Nature communications (17.05.2019)
Published in Nature communications (17.05.2019)
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Journal Article
Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension
Savai, Rajkumar, Al-Tamari, Hamza M, Sedding, Daniel, Kojonazarov, Baktybek, Muecke, Christian, Teske, Rebecca, Capecchi, Mario R, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Schermuly, Ralph Theo, Pullamsetti, Soni Savai
Published in Nature medicine (01.11.2014)
Published in Nature medicine (01.11.2014)
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Journal Article
ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension
Budas, Grant R, Boehm, Mario, Kojonazarov, Baktybek, Viswanathan, Gayathri, Tian, Xia, Veeroju, Swathi, Novoyatleva, Tatyana, Grimminger, Friedrich, Hinojosa-Kirschenbaum, Ford, Ghofrani, Hossein A, Weissmann, Norbert, Seeger, Werner, Liles, John T, Schermuly, Ralph T
Published in American journal of respiratory and critical care medicine (01.02.2018)
Published in American journal of respiratory and critical care medicine (01.02.2018)
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Journal Article
Amplified canonical transforming growth factor-β signalling via heat shock protein 90 in pulmonary fibrosis
Sibinska, Zaneta, Tian, Xia, Korfei, Martina, Kojonazarov, Baktybek, Kolb, Janina Susanne, Klepetko, Walter, Kosanovic, Djuro, Wygrecka, Malgorzata, Ghofrani, Hossein Ardeschir, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Guenther, Andreas, Schermuly, Ralph T
Published in The European respiratory journal (01.02.2017)
Published in The European respiratory journal (01.02.2017)
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Journal Article
Insights into the Black Box of Intra-Amniotic Infection and Its Impact on the Premature Lung: From Clinical and Preclinical Perspectives
Dong, Ying, Rivetti, Stefano, Lingampally, Arun, Tacke, Sabine, Kojonazarov, Baktybek, Bellusci, Saverio, Ehrhardt, Harald
Published in International journal of molecular sciences (01.09.2022)
Published in International journal of molecular sciences (01.09.2022)
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Journal Article
p38 MAPK Inhibition Improves Heart Function in Pressure-Loaded Right Ventricular Hypertrophy
Kojonazarov, Baktybek, Novoyatleva, Tatyana, Boehm, Mario, Happe, Chris, Sibinska, Zaneta, Tian, Xia, Sajjad, Amna, Luitel, Himal, Kriechling, Philipp, Posern, Guido, Evans, Steven M, Grimminger, Friedrich, Ghofrani, Hossein A, Weissmann, Norbert, Bogaard, Harm J, Seeger, Werner, Schermuly, Ralph T
Published in American journal of respiratory cell and molecular biology (01.11.2017)
Published in American journal of respiratory cell and molecular biology (01.11.2017)
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Journal Article
Inhibition of MicroRNA-17 Improves Lung and Heart Function in Experimental Pulmonary Hypertension
PULLAMSETTI, Soni S, DOEBELE, Carmen, SEEGER, Werner, ZEIHER, Andreas M, DIMMELER, Stefanie, SCHERMULY, Ralph T, FISCHER, Ariane, SAVAI, Rajkumar, KOJONAZAROV, Baktybek, DAHAL, Bhola K, GHOFRANI, Hossein A, WEISSMANN, Norbert, GRIMMINGER, Friedrich, BONAUER, Angelika
Published in American journal of respiratory and critical care medicine (15.02.2012)
Published in American journal of respiratory and critical care medicine (15.02.2012)
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Journal Article
The soluble guanylate cyclase stimulator riociguat ameliorates pulmonary hypertension induced by hypoxia and SU5416 in rats
Lang, Michaela, Kojonazarov, Baktybek, Tian, Xia, Kalymbetov, Anuar, Weissmann, Norbert, Grimminger, Friedrich, Kretschmer, Axel, Stasch, Johannes-Peter, Seeger, Werner, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo
Published in PloS one (17.08.2012)
Published in PloS one (17.08.2012)
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Journal Article
Riociguat for treatment of pulmonary hypertension in COPD: a translational study
Pichl, Alexandra, Sommer, Natascha, Bednorz, Mariola, Seimetz, Michael, Hadzic, Stefan, Kuhnert, Stefan, Kraut, Simone, Roxlau, Elsa T, Kojonazarov, Baktybek, Wilhelm, Jochen, Gredic, Marija, Gall, Henning, Tello, Khodr, Richter, Manuel J, Pak, Oleg, Petrovic, Aleksandar, Hecker, Matthias, Schermuly, Ralph T, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein A, Weissmann, Norbert
Published in The European respiratory journal (01.06.2019)
Published in The European respiratory journal (01.06.2019)
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Journal Article
Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)
Lu, Shun, Liu, Shuya, Wietelmann, Astrid, Kojonazarov, Baktybek, Atzberger, Ann, Tang, Cong, Schermuly, Ralph Theo, Gröne, Hermann-Josef, Offermanns, Stefan
Published in PloS one (14.08.2017)
Published in PloS one (14.08.2017)
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Journal Article
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life
Selle, Jaco, Dinger, Katharina, Jentgen, Vanessa, Zanetti, Daniela, Will, Johannes, Georgomanolis, Theodoros, Vohlen, Christina, Wilke, Rebecca, Kojonazarov, Baktybek, Klymenko, Oleksiy, Mohr, Jasmine, v. Koningsbruggen-Rietschel, Silke, Rhodes, Christopher J., Ulrich, Anna, Hirani, Dharmesh, Nestler, Tim, Odenthal, Margarete, Mahabir, Esther, Nayakanti, Sreenath, Dabral, Swati, Wunderlich, Thomas, Priest, James, Seeger, Werner, Dötsch, Jörg, Pullamsetti, Soni S., Alejandre Alcazar, Miguel A.
Published in Nature communications (27.07.2022)
Published in Nature communications (27.07.2022)
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Journal Article
Effect of p53 activation on experimental right ventricular hypertrophy
Veeroju, Swathi, Mamazhakypov, Argen, Rai, Nabham, Kojonazarov, Baktybek, Nadeau, Valerie, Breuils-Bonnet, Sandra, Li, Ling, Weissmann, Norbert, Rohrbach, Susanne, Provencher, Steve, Bonnet, Sébastien, Seeger, Werner, Schermuly, Ralph, Novoyatleva, Tatyana
Published in PloS one (19.06.2020)
Published in PloS one (19.06.2020)
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Journal Article
Activation of Humoral Immunity during the Pathogenesis of Experimental Chronic Lung Allograft Dysfunction
Reichert, Martin, Atanasova, Srebrena, Petri, Kathrin, Kampschulte, Marian, Kojonazarov, Baktybek, Fuchs-Moll, Gabriele, Krombach, Gabriele A., Padberg, Winfried, Grau, Veronika
Published in International journal of molecular sciences (01.08.2022)
Published in International journal of molecular sciences (01.08.2022)
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Journal Article
Effect of Riociguat and Sildenafil on Right Heart Remodeling and Function in Pressure Overload Induced Model of Pulmonary Arterial Banding
Seeger, Werner, Schermuly, Ralph Theo, Novoyatleva, Tatyana, Stasch, Johannes-Peter, Weissmann, Norbert, Kojonazarov, Baktybek, Wietelmann, Astrid, Janssen, Wiebke, Schymura, Yves, Veeroju, Swathi, Rai, Nabham, Ghofrani, Ardeschir
Published in BioMed research international (01.01.2018)
Published in BioMed research international (01.01.2018)
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Journal Article
Genetic Deficiency and Pharmacological Stabilization of Mast Cells Ameliorate Pressure Overload-Induced Maladaptive Right Ventricular Remodeling in Mice
Sydykov, Akylbek, Luitel, Himal, Mamazhakypov, Argen, Wygrecka, Malgorzata, Pradhan, Kabita, Pak, Oleg, Petrovic, Aleksandar, Kojonazarov, Baktybek, Weissmann, Norbert, Seeger, Werner, Grimminger, Friedrich, Ghofrani, Hossein Ardeschir, Kosanovic, Djuro, Schermuly, Ralph Theo
Published in International journal of molecular sciences (30.11.2020)
Published in International journal of molecular sciences (30.11.2020)
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Journal Article
Therapeutic Potential of Regorafenib-A Multikinase Inhibitor in Pulmonary Hypertension
Veeroju, Swathi, Kojonazarov, Baktybek, Weiss, Astrid, Ghofrani, Hossein Ardeschir, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Novoyatleva, Tatyana, Schermuly, Ralph T
Published in International journal of molecular sciences (02.02.2021)
Published in International journal of molecular sciences (02.02.2021)
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Journal Article
Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension
Boehm, Mario, Arnold, Nadine, Braithwaite, Adam, Pickworth, Josephine, Lu, Changwu, Novoyatleva, Tatyana, Kiely, David G, Grimminger, Friedrich, Ghofrani, Hossein A, Weissmann, Norbert, Seeger, Werner, Lawrie, Allan, Schermuly, Ralph T, Kojonazarov, Baktybek
Published in BMC pulmonary medicine (02.03.2018)
Published in BMC pulmonary medicine (02.03.2018)
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Journal Article
PAR-2 Inhibition Reverses Experimental Pulmonary Hypertension
Kwapiszewska, Grazyna, Markart, Philipp, Dahal, Bhola Kumar, Kojonazarov, Baktybek, Marsh, Leigh Matthew, Schermuly, Ralph Theo, Taube, Christian, Meinhardt, Andreas, Ghofrani, Hossein Ardeschir, Steinhoff, Martin, Seeger, Werner, Preissner, Klaus Theo, Olschewski, Andrea, Weissmann, Norbert, Wygrecka, Malgorzata
Published in Circulation research (27.04.2012)
Published in Circulation research (27.04.2012)
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Journal Article
Correction to: Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension
Boehm, Mario, Arnold, Nadine, Braithwaite, Adam, Pickworth, Josephine, Lu, Changwu, Novoyatleva, Tatyana, Kiely, David G, Grimminger, Friedrich, Ghofrani, Hossein A, Weissmann, Norbert, Seeger, Werner, Lawrie, Allan, Schermuly, Ralph T, Kojonazarov, Baktybek
Published in BMC pulmonary medicine (20.07.2022)
Published in BMC pulmonary medicine (20.07.2022)
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Journal Article
The F-BAR Protein NOSTRIN Dictates the Localization of the Muscarinic M3 Receptor and Regulates Cardiovascular Function
Kovacevic, Igor, Müller, Miriam, Kojonazarov, Baktybek, Ehrke, Alexander, Randriamboavonjy, Voahanginirina, Kohlstedt, Karin, Hindemith, Tanja, Schermuly, Ralph Theo, Fleming, Ingrid, Hoffmeister, Meike, Oess, Stefanie
Published in Circulation research (14.08.2015)
Published in Circulation research (14.08.2015)
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Journal Article